Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00377143
Details
2012-02-16
Interventional
40 
Warfarin
Blood Coagulati… Hemostatic Diso…
similar large study planned by NHLBI
-
NCT00040014
Details
2012-02-16
Interventional
2-
Exemestane
Breast Neoplasm…
-
-
NCT00936195
Details
2012-02-15
Interventional
30 
Efavirenz Emtricitabine Lamivudine Lamivudine, zid… Lopinavir Ritonavir Tenofovir Zidovudine
Acquired Immuno… Communicable Di… HIV Infections Infections Breastfeeding HIV Infection Pregnancy
faillure to obtain insurance because of refusal from insurance companies
-
NCT00368381
Details
2012-02-13
Interventional
4
[15 Refs]
0 
Hydrocortisone
Adrenal Insuffi… Sepsis Toxemia
Study closed for PI failure to submit renewal paperwork
-
NCT01452009
Details
2012-02-10
Interventional
30 
Ophthalmic Solu… Travoprost
Glaucoma Glaucoma, Open-… Hypertension Ocular Hyperten… Open Angle Glau…
Management Decision
-
NCT00389090
Details
2012-02-09
Interventional
232 
O(6)-benzylguan… Temozolomide
Astrocytoma Glioma Oligodendroglio… Oligoastrocytom…
AOI Pharma terminated the license agreement. IND Transferred to NCI
-
NCT01273779
Details
2012-02-03
Interventional
2/3-
Talactoferrin a…
Sepsis Toxemia Severe Sepsis
Data Safety Monitoring Board recommendation
-
NCT00762359
Details
2012-02-03
Interventional
3461 
Dexlansoprazole Gefarnate Lansoprazole
Duodenal Ulcer Stomach Ulcer Ulcer
AG-1749 superior to Gefarnate in ulcer prevention
On September 2008, the Efficacy and Safety Evaluation Committee recommended that this study be discontinued based on the interim analysis.
NCT00134264
Details
2012-02-03
Interventional
315067 
Atorvastatin Torcetrapib
Coronary Diseas… Heart Diseases Diabetes Mellit…
-
-
NCT00124748
NCT00324636
Details
2012-02-03
Interventional
3476 
Imatinib Mesyla…
Leukemia Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo…
This study was prematurely discontinued because no improvement was observed in the 800mg dose compared to 400mg dose
-
NCT00759720
Details
2012-02-02
Interventional
3447 
Glyburide
Diabetes Mellit… Diabetes Mellit…
Potential hepatic safety signal
-
NCT01132404
2009-017668-18
Details
2012-01-31
Interventional
1/29 
Leuprolide
Prostatic Neopl… Prostate Cancer
Developing new formulation of study drug. New study to open next year under a new protocol.
-
NCT00969033
Details
2012-01-31
Interventional
28 
Irinotecan
Colorectal Neop… Metastatic Colo…
-
-
NCT00763685
2008-004098-17
Details
2012-01-31
Interventional
440 
Etoricoxib
Pain, Postopera… Pain
The gynecological laparoscopic surgery transition to day surgery made following the study protocol not possible.
-
NCT01254136
Details
2012-01-25
Interventional
1/2-
Trastuzumab Vinorelbine
Breast Neoplasm… Breast Cancer
Incyte has suspended development of the compound.
-
NCT00613808
Details
2012-01-25
Interventional
26 
Nitric Oxide
Ulcer Varicose Ulcer Venous Ulcers
-
-
NCT00446303
Details
2012-01-19
Interventional
239 
Azacitidine
Leukemia, Myelo… Leukemia, Myelo… Myelodysplastic… Preleukemia Leukemia, Myelo…
-
-
NCT00862472
Details
2012-01-18
Interventional
30 
Cloprostenol Timolol
Glaucoma Glaucoma, Open-… Hypertension Ocular Hyperten… Open-angle Glau…
Management decision not to conduct an additional efficacy study.
-
NCT01510288
Details
2012-01-16
Interventional
128 
Ipilimumab
Prostatic Neopl… Prostate Cancer
The study was terminated because Cell Genesys stopped all activities for GVAX.
-
NCT01015729
Details
2012-01-16
Interventional
130 
Esomeprazole
Peptic Ulcer Peptic Ulcer Di…
-
-