Trials Annotator

Barber AE, Coyle SM, Fischer E, Smith C, van der Poll T, Shires GT, Lowry SF. Influence of hypercortisolemia on soluble tumor necrosis factor receptor II and interleukin-1 receptor antagonist responses to endotoxin in human beings. Surgery. 1995 Aug;118(2):406-10; discussion 410-1. doi: 10.1016/s0039-6060(05)80352-6. [PMID: 7638758] [DOI: 10.1016/s0039-6060(05)80352-6]
van der Poll T, Barber AE, Coyle SM, Lowry SF. Hypercortisolemia increases plasma interleukin-10 concentrations during human endotoxemia--a clinical research center study. J Clin Endocrinol Metab. 1996 Oct;81(10):3604-6. doi: 10.1210/jcem.81.10.8855809. [PMID: 8855809] [DOI: 10.1210/jcem.81.10.8855809]
Bone RC, Fisher CJ Jr, Clemmer TP, Slotman GJ, Metz CA, Balk RA. A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock. N Engl J Med. 1987 Sep 10;317(11):653-8. doi: 10.1056/NEJM198709103171101. [PMID: 3306374] [DOI: 10.1056/NEJM198709103171101]
Sprung CL, Caralis PV, Marcial EH, Pierce M, Gelbard MA, Long WM, Duncan RC, Tendler MD, Karpf M. The effects of high-dose corticosteroids in patients with septic shock. A prospective, controlled study. N Engl J Med. 1984 Nov 1;311(18):1137-43. doi: 10.1056/NEJM198411013111801. [PMID: 6384785] [DOI: 10.1056/NEJM198411013111801]
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Cronin L, Cook DJ, Carlet J, Heyland DK, King D, Lansang MA, Fisher CJ Jr. Corticosteroid treatment for sepsis: a critical appraisal and meta-analysis of the literature. Crit Care Med. 1995 Aug;23(8):1430-9. doi: 10.1097/00003246-199508000-00019. [PMID: 7634816] [DOI: 10.1097/00003246-199508000-00019]
Thomas JP, el-Shaboury AH. Aldosterone secretion in steroid-treated patients with adrenal suppression. Lancet. 1971 Mar 27;1(7700):623-5. doi: 10.1016/s0140-6736(71)91554-6. No abstract available. [PMID: 4101232] [DOI: 10.1016/s0140-6736(71)91554-6]
Briegel J, Forst H, Haller M, Schelling G, Kilger E, Kuprat G, Hemmer B, Hummel T, Lenhart A, Heyduck M, Stoll C, Peter K. Stress doses of hydrocortisone reverse hyperdynamic septic shock: a prospective, randomized, double-blind, single-center study. Crit Care Med. 1999 Apr;27(4):723-32. doi: 10.1097/00003246-199904000-00025. [PMID: 10321661] [DOI: 10.1097/00003246-199904000-00025]
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Trial NCT00368381

MeSH Interventions

MeSH Conditions

Other Conditions

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