Trial NCT03510455

View at ClinicalTrials.gov 
Org. Study IDs: 180086
Secondary IDs: 18-D-0086

Last trial update was posted on 2021-04-08

MeSH Interventions

Infigratinib

MeSH Conditions

Neoplasms, Connective Tissue Osteomalacia

Other Conditions

Oncogenic Osteomalacia Tumor-Induced Osteomalacia

Stopping Reasons

Study was stopped early due to a greater than expected incidence of ocular AEs and analysis of the data from the first 4 subjects indicating that the likelihood of permanent remission with this therapy was low.

Limitations And Caveats

This study was terminated early due to a lack of efficacy in the first 4 patients and an unexpectedly high rate of ocular adverse events. As a result, only 4 patients were enrolled in this study. Because of the small sample size, we were unable to perform the planned statistical analysis, and instead the results are primarily descriptive.

Result Publications

N/A

Annotations

Category Annotations
No annotators decided on categories yet

Intervention Annotations
# Outdated Intervention Condition
Name Route DrugBank ID