Trial NCT00387348

View at ClinicalTrials.gov 
Org. Study IDs: CDR0000505774
Secondary IDs: K23CA115908 MGH-2006-P-000299

Last trial update was posted on 2012-12-03

MeSH Interventions

Citalopram Dexetimide Escitalopram

MeSH Conditions

Bile Duct Neoplasms Cholangiocarcinoma Depression Depressive Disorder Esophageal Neoplasms Fatigue Gallbladder Neoplasms Liver Neoplasms Lung Neoplasms Pancreatic Neoplasms Stomach Neoplasms

Other Conditions

Colorectal Cancer Esophageal Cancer Extrahepatic Bile Duct Cancer Gallbladder Cancer Gastric Cancer Liver Cancer Lung Cancer Pancreatic Cancer

Stopping Reasons

DSMB stopped study because placebo arm had more adverse events

Limitations And Caveats

After an interim analaysis, the DSMB decided to terminate the trial early because of the rate of adverse events (HAM-D scores increasing by at least 25%) and deaths were higher in participants receiving placebo.

Result Publications

N/A

Annotations

Category Annotations
No annotators decided on categories yet

Intervention Annotations
# Outdated Intervention Condition
Name Route DrugBank ID