Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT03992443
2021-004026-30
Details
2022-04-15
Interventional
30 
Reteplase
Restoration of …
Chiesi business decision
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NCT04272333
Details
2022-04-14
Interventional
11 
Nivolumab
Squamous Cell C… HNSCC
Partner Termination
-
NCT03191526
Details
2022-04-14
Interventional
366 
Mogamulizumab
Bone Marrow Dis… Paraparesis, Tr… Spinal Cord Dis… HTLV-1 Associat…
Due to not achieving the primary outcome.
-
NCT03041701
Details
2022-04-14
Interventional
1/214 
Dasatinib
Rhabdomyosarcom… Rhabdomyosarcom… Rhabdomyosarcom…
The pharmaceutical company discontinued availability of the drug and we were forced to close the study before phase II was completed. Only one participant was enrolled on phase II.
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NCT03021083
Details
2022-04-14
Interventional
40 
Fentanyl
Spinal Injuries Spinal Injury
Contract not reached with sponsor
-
NCT02945813
2016-003599-39
Details
2022-04-14
Interventional
2112 
Metformin
Prostatic Neopl… Prostate Cancer
Trial was prematurely closed for accrual by the SAKK Board and the follow-up period shortened to one year after last RT fraction of the last patient
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NCT01766128
Details
2022-04-14
Interventional
2/30 
Zonisamide
Parkinson Disea…
Practical problems
-
NCT04421664
Details
2022-04-13
Interventional
3
[2 Refs]
70 
Hydroxychloroqu…
COVID-19 Communicable Di… Coronavirus Inf… Infections Severe Acute Re… Corona Virus In… Coronavirus SARS-CoV Infect…
Request of Health Canada after publication of https://doi.org/10.7326/M20-4207
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NCT05295394
Details
2022-04-12
Interventional
40 
Dolutegravir Lamivudine
HIV-1 Infection
Low recruitment, We did not find participants with the M184V mutation , inclusion criteria , throughout 230 resistance tests carried out
-
NCT04965272
Details
2022-04-12
Interventional
20 
Cariprazine
Anxiety Disorde… Generalized Anx…
Strategic Decision
-
NCT04336748
Details
2022-04-12
Interventional
30 
Hydroxychloroqu…
Virus Diseases Healthcare Work… Infection Viral Prophylaxis Sars-CoV2
Not feasible
-
NCT03950037
Details
2022-04-12
Interventional
20 
Albendazole
Cysticercosis Neurocysticerco… Taeniasis Subarachnoid Ne…
Unable to complete due to SARS-CoV-2 pandemic
-
NCT03434366
Details
2022-04-12
Interventional
2-
Dexmedetomidine Ketamine
Autism Spectrum… Autistic Disord… Child Developme…
The effects are not good
-
NCT00286169
Details
2022-04-12
Interventional
3-
Amrubicin
Lung Neoplasms Small Cell Lung… Small-cell Lung…
-
-
NCT03707028
Details
2022-04-11
Interventional
1/212 
Apatinib Paclitaxel
Adenocarcinoma Gastric Cancer Gastroesophagea…
Terminated after completion of Part 1 due to a change in research plan.
-
NCT03593213
NCT04519099
2017-000818-34
Details
2022-04-11
Interventional
3587 
Cariprazine
Schizophrenia
FDA Released Allergan from this post marketing requirement
-
NCT03532022
Details
2022-04-08
Interventional
30 
Dexamethasone Hydrocortisone Hydrocortisone … Hydrocortisone … Hydrocortisone … Prednisolone Prednisone
Adrenal Hyperpl… Adrenogenital S… Hyperplasia Congenital Adre…
Protocol re-design required following EU Phase III results
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NCT02384850
Details
2022-04-08
Interventional
110 
Fluorouracil Folic Acid Leucovorin Levoleucovorin Oxaliplatin
Colorectal Neop… Colorectal Neop…
-
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NCT04471714
Details
2022-04-07
Interventional
20 
Baclofen
Muscle Spastici… Spinal Cord Inj… Spasticity, Mus…
Study recruitment was halted due to restrictions and we have decided to not pursue it further.
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NCT04246619
2017-004341-24
Details
2022-04-07
Interventional
4254 
Duloxetine Hydr… Pregabalin
Diabetic Neurop… Pain Peripheral Nerv… Painful Diabeti…
The statistical analysis will still provide relevant results with the same statistical power as initially planned.COVID-19 pandemic prolonged the recruiting period and consequently affected the costs of the clinical trial.
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