Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT03294252
Details
2022-04-25
Interventional
1/234 
Fluorouracil Folic Acid Leucovorin Levoleucovorin Oxaliplatin
Gastrointestina… Neoplasm Metast… Digestive Cance…
The 34 patients included had all completed their treatment period under the protocol and the data could be collected to assess the main objective and the secondary objectives before the last theoretical follow-up.
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NCT03148756
Details
2022-04-25
Interventional
22 
Dalbavancin
Bacteremia Endocarditis Endocarditis, B…
Study stopped due to business reasons.
-
NCT05157997
Details
2022-04-22
Interventional
10 
Antibodies Casirivimab and…
COVID-19 Organ Transplan…
New information regarding COVID-19
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NCT04369742
Details
2022-04-22
Interventional
2128 
Calcium Hydroxychloroqu…
COVID-19
Investigator decision
-
NCT03364686
Details
2022-04-21
Interventional
26 
Biotin
Healthy Volunte…
Due to enrollment challenges related to COVID and lack of coordinator support
The clinical trial was terminated early due to challenges with enrollment and lack of study coordinator support. Early termination leading to small numbers of subjects analyzed.
NCT02937766
Details
2022-04-21
Interventional
360 
11-hydroxyproge… 17 alpha-Hydrox…
Assessing Injec…
The Sponsor elected to discontinue the study prematurely due to business reasons
The Sponsor elected to discontinue the study prematurely due to business reasons. The only parameters analyzed for efficacy were Ease of Drug Preparation and Ease of Injection Technique.
NCT02927938
Details
2022-04-21
Interventional
318 
Cytarabine
Leukemia Leukemia, Myelo… Leukemia, Myelo… Acute Myeloid L…
Study terminated 7/23/2019 due to limited participation and testing challenges.
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NCT02719392
Details
2022-04-21
Interventional
4-
Acetylcysteine Minocycline N-monoacetylcys…
Bipolar Disorde… Depression Depressive Diso… Bipolar Depress…
Due to limited study staff and the COVID-19 pandemic, enrollment has been paused as staff hours for this project have been reduced and reallocated to other projects.
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NCT04371952
Details
2022-04-20
Interventional
30 
Doxycycline
COVID-19 COVID19
withdrawal due to the evolution of the epidemic, the arrival of vaccination and because the associated centres could no longer commit to the number of inclusions requested
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NCT03365752
Details
2022-04-20
Interventional
239 
Anesthetics Anesthetics, Ge… Chloroprocaine Mepivacaine
Knee Arthroscop…
Study halted due to COVID-19 pandemic and terminated early per request of principal investigator as Chloroprocaine use in spinal procedures has become incorporated as standard of care at HSS.
This project was terminated early, as enrollment was negatively impacted to due to the COVID-19 pandemic and because clinical practice has shifted to include the use of chloroprocaine in spinal procedures as standard of care at the Hospital for Special Surgery.
NCT02897050
Details
2022-04-20
Interventional
2-
Capecitabine Cyclophosphamid… Docetaxel Epirubicin Fluorouracil
Breast Neoplasm… Triple Negative… Breast Cancer
-
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NCT04919096
Details
2022-04-19
Interventional
10 
Aflibercept
Macular Degener… Wet Age-related…
Due to an internal decision to prioritise its development pipeline, Clover have decided to close down study CLO-SCB-420-001. This was a corporate decision and not the results of new data or information arising related to SCB-420
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NCT04388683
Details
2022-04-19
Interventional
210 
Nitric Oxide
COVID-19
Bellerophon requested study to be stopped.
The study was terminated early by request of the company providing the iNO Drug. Our data set is small are analysis was effected by this.
NCT03787251
Details
2022-04-19
Interventional
20 
Apatinib
Esophageal Neop… Recurrence
In China, apatinib has been approved as an indication drug for esophageal squamous cell carcinoma, which makes it very difficult for our clinical trial to enroll patients. We regret that we failed to implement the design as planned.
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NCT02588248
Details
2022-04-19
Interventional
382 
Menthol Peppermint oil
Colonic Neoplas… Colonic Polyps Colon Cancer
Sponsor/Investigator has decided to close out the study
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NCT04286529
Details
2022-04-18
Interventional
117 
Calcitriol
Prediabetic Sta… Pre-Diabetic
Difficulty with study logistics due to COVID-19
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NCT03936192
Details
2022-04-18
Interventional
30 
Meloxicam
Osteoarthritis Osteoarthritis,… Knee Osteoarthr…
Company decision
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NCT04901689
Details
2022-04-15
Interventional
3-
Leronlimab
COVID-19 Pneumonia COVID-19 Pneumo…
Pending DSMB evaluation
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NCT04901676
Details
2022-04-15
Interventional
3-
Leronlimab
COVID-19 Pneumonia COVID-19 Pneumo…
Pending DSMB evaluation
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NCT04592991
Details
2022-04-15
Interventional
11 
1,4,7,10-tetraa…
Aneurysm Aortic Aneurysm Aortic Aneurysm… Abdominal Aorti…
We were only able to enroll 1 subject so we had no way to compare a control or other study groups and develop any kind of results. This study is essentially the same study as NCT04586452, which we would like to place focus and effort on that study.
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