Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01461915
Details
2022-06-06
Interventional
260 
Gemcitabine Heparin Paclitaxel
Pancreatic Neop… Metastatic Panc…
-
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NCT00754312
Details
2022-06-06
Interventional
11 
Entinostat
Breast Neoplasm… Breast Cancer
-
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NCT04592159
2020-000527-39
Details
2022-06-03
Interventional
2/30 
Nabiximols
Stress Disorder… Stress Disorder… Post-Traumatic …
The decision to suspend this study was based upon evaluation of pandemic-related challenges impacting both clinical trial sites and potential participants. This suspension was initiated prior to site activation and participant recruitment.
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NCT04314713
Details
2022-06-03
Interventional
132 
Butylscopolammo… Scopolamine
Scopolamine Cau…
DSMB decision due to adverse events
-
NCT02514031
Details
2022-06-03
Interventional
117 
Beta-lapachone Gemcitabine Paclitaxel
Pancreatic Neop… Pancreatic Canc…
The study placed on temporarily hold to enrollment due to quality testing necessary for the study drug.
-
NCT04796454
Details
2022-06-01
Interventional
20 
Gemcitabine Oxaliplatin Pamiparib Temozolomide
Biliary Tract N… Hypersensitivit… Platinum-Sensit…
Company decision
-
NCT04178460
Details
2022-06-01
Interventional
160 
Niraparib
Carcinoma Endometrial Neo… Triple Negative… Biliary Tract C… Endometrial Car… Gastric Cancer Triple Negative…
This termination decision is a business decision and is not due to any safety concerns.
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NCT03986996
Details
2022-06-01
Interventional
220 
Amoxicillin Doxycycline Metronidazole
Colitis Colitis, Ulcera… Ulcer Ulcerative Coli…
There is no feasibility to conduct the study
-
NCT05238844
Details
2022-05-31
Interventional
22 
Tenofovir
Hepatitis Hepatitis A Hepatitis B Hepatitis B, Ch… Hepatitis, Chro… Herpesviridae I… Virus Diseases Chronic Hepatit…
Sponsor stopped due to partner collaboration ending
-
NCT05082155
Details
2022-05-31
Interventional
40 
Bupivacaine
Acute Pain Pain, Postopera… Surgical Wound Pain, Acute Surgical Incisi…
surgeons stopped doing procedures
-
NCT03757897
Details
2022-05-31
Interventional
10 
Dexmedetomidine
Intracranial Hy… Cerebrospinal F…
The investigators were unable to implement a MRI compatible EEG for use in human subjects (equipment and technical issues).
-
NCT03608358
Details
2022-05-31
Interventional
341 
Dapagliflozin Metformin Saxagliptin
Diabetes Mellit… Type 2 Diabetes…
Sponsor decided to stop commercialization of QTERNMet/Qtrilmet and to stop all related ongoing activities/studies for business reasons.
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NCT01887522
2012-003005-10
Details
2022-05-31
Interventional
2144 
Nilotinib Vinblastine
Glioma Recurrent Low-g… Refractory Low-…
the results of the interim analysis are clear with a significant advantage in terms of PFS in favor of the control arm (Vinblastine alone) over the investigational arm (Vinblastine + Nilotinib).
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NCT05017584
Details
2022-05-27
Interventional
40 
Bupivacaine
Pain
Study halted prematurely, prior to enrollment of first participant
-
NCT04671836
Details
2022-05-27
Interventional
1
[2 Refs]
0 
Lorazepam
Lorazepam Neuroimaging
No longer interested in conducing study
-
NCT02940509
Details
2022-05-27
Interventional
120 
Ketamine Magnesium Sulfa…
Chronic Pain Pain, Postopera…
Change in practice of medicine. There were no longer sufficient patients to enroll in the study that met criteria.
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NCT02150785
Details
2022-05-27
Interventional
20 
Streptokinase
Ischemic Stroke Stroke
Could not get study started.
-
NCT02144831
Details
2022-05-27
Interventional
40 
Aspirin Clopidogrel
Ischemia Ischemic Attack… Minor Stroke Transient Ische…
Could not get study started
-
NCT04753957
Details
2022-05-26
Interventional
13 
Progesterone
Pregnancy Relat…
Difficulty with endometrial sample collection. New study design to be prospective observational to validate reliable methods of endometrial sampling at time of c-section.
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NCT03712345
Details
2022-05-26
Interventional
220 
Vilobelimab
Granulomatosis … Microscopic Pol… Systemic Vascul… Granulomatosis … Microscopic Pol…
Due to COVID-19 pandemic outbreak and its impact on overall study activities. All efforts were made to ensure that participants that were enrolled and/or were still in the study will continue to receive treatment and follow-up until study completion.
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