Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

Filter:

Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
Free Text
Annotations

7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT03147040
Details
2022-07-19
Interventional
223 
Atezolizumab Carboplatin
Breast Neoplasm… Breast Cancer
At interim analysis insufficient benefit was observed to continu the study
-
NCT02933671
Details
2022-07-19
Interventional
411 
Ropivacaine
Osteoarthritis,… Hip Osteoarthri… Pain Primary Total H…
Study halted prematurely and will not resume; participants are no longer being examined or receiving any intervention.
-
NCT02832531
Details
2022-07-19
Interventional
30 
Aspirin Rivaroxaban
Heart Diseases Rheumatic Disea… Rheumatic Heart…
Focus on recruitment for non-inferiority trial
-
NCT02325349
2014-000553-37
Details
2022-07-19
Interventional
21 
Radiopharmaceut…
Carcinoma Carcinoma, Non-… Head and Neck N… Advanced Head a… Advanced Non-sm…
Change in protocol strategy
-
NCT04796922
Details
2022-07-18
Interventional
30 
Obinutuzumab Rituximab
Lymphoma Lymphoma, B-Cel… Lymphoma, Folli… Follicular Lymp… Marginal Zone L…
This study was withdrawn due to a business decision.
-
NCT02569489
Details
2022-07-18
Interventional
10 
Paclitaxel Trastuzumab
Breast Neoplasm… Breast Cancer
Reconsideration of Study Design; plan for alternative protocol
-
NCT02201381
Details
2022-07-18
Interventional
30 
Atorvastatin Doxycycline Mebendazole Metformin
Cancer Overall Surviva…
Prospective recruitment not possible
-
NCT01773395
Details
2022-07-18
Interventional
2123 
Busulfan Fludarabine Methotrexate Tacrolimus
Leukemia Leukemia, Myelo… Leukemia, Myelo… Myelodysplastic… Acute Myeloid L… Chronic Myelomo… Myelodysplastic…
Recommendation by the Data and Safety Monitoring Board due to efficacy concerns
-
NCT04596033
Details
2022-07-15
Interventional
149 
Cyclophosphamid… Fludarabine Interleukin-2
Carcinoma Carcinoma, Merk… Carcinoma, Squa… Lung Neoplasms Melanoma Small Cell Lung… Squamous Cell C… Anal Squamous C… Cutaneous Squam… Merkel Cell Car… Non-small Cell … Renal Cell Carc… Small-cell Lung… Urothelial Carc…
Business reasons
-
NCT03263767
Details
2022-07-15
Interventional
247 
Clofarabine Cyclophosphamid… Fludarabine Thymoglobulin
Graft vs Host D… Graft Versus Ho…
Security criteria (MTD)
-
NCT03754140
Details
2022-07-14
Interventional
20 
Polidocanol
Melanoma Melanoma, Cutan… Neoplasm Metast… Skin Neoplasms In-Transit Meta…
Unable to identify eligible patients within planned timeframe
-
NCT01370486
Details
2022-07-14
Interventional
40 
Melatonin
Lennox Gastaut … Syndrome Lennox-Gastaut …
The study did not received the approbation from Swissmedic. Therefore, the recruitment of participants never started.
-
NCT03365414
Details
2022-07-13
Interventional
30 
Pharmaceutical …
Postural Orthos… Syndrome Tachycardia
Withdrawal of support of product for trial
-
NCT02340221
2014-003185-25
Details
2022-07-12
Interventional
3631 
Fulvestrant
Breast Neoplasm… Recurrence Breast Cancer
The Sponsor discontinued the manufacturing and development of taselisib due to modest clinical benefit and limited tolerability.
-
NCT05227131
2021-006387-24
Details
2022-07-11
Interventional
20 
Capecitabine Margetuximab Tucatinib
Breast Neoplasm… Advanced Breast… HER2-positive B… Metastatic Brea…
Funder decided to not continue the study
-
NCT04891718
Details
2022-07-08
Interventional
10 
Nivolumab
Solid Tumour
Termination by pharmaceutical sponsor
-
NCT02535247
Details
2022-07-08
Interventional
1/2
[1 Refs]
17 
Pembrolizumab
Lymphoma Lymphoma, Non-H… Lymphoma, T-Cel… Lymphoma, T-Cel…
Merck no longer providing drug for study
-
NCT05062577
Details
2022-07-07
Interventional
20 
ASP8062 Buprenorphine Buprenorphine, … Naloxone
Opioid-Related … Substance-Relat… Opioid Use Diso…
Due to corporate strategic considerations
-
NCT01555281
2010-022035-11
Details
2022-07-07
Interventional
1/233 
Dexamethasone Lenalidomide Nelfinavir
Multiple Myelom… Neoplasms, Plas…
In connection with the restructuring of SAKK, older ongoing studies were analyzed to determine whether a continuation of the trial would still add value to the data analysis, or whether they do not and could therefore be prematurely terminated.
-
NCT05002114
Details
2022-07-06
Interventional
10 
Cannabidiol
Arthralgia Musculoskeletal…
there were issues with the primary study material that prohibited continuation at this time
-