Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

Filter:

Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
Free Text
Annotations

7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT04639843
Details
2022-11-04
Interventional
10 
Azacitidine Cc-486 Doxorubicin Romidepsin
Enteropathy-Ass… Leukemia, T-Cel… Leukemia-Lympho… Lymphoma Lymphoma, Extra… Lymphoma, T-Cel… Lymphoma, T-Cel… Adult T-cell Le… Extranodal NK-/… Hepatosplenic T… Monomorphic Epi…
Safety issues with PI3 kinase inhibitors
-
NCT04242173
Details
2022-11-04
Interventional
23 
Cemiplimab
Carcinoma Carcinoma, Squa… Squamous Cell C… Cutaneous Squam… Cutaneous Squam…
Lack of Interest
-
NCT04135352
2020-003431-25
Details
2022-11-04
Interventional
135 
Pembrolizumab
Neoplasm Metast…
Business Reasons
-
NCT03518112
Details
2022-11-04
Interventional
26 
Antibodies Antibodies, Bis… Antibodies, Mon… Antineoplastic … BB 1101 Blinatumomab Calcium Calcium, Dietar… Cyclophosphamid… Cytarabine Dexamethasone Dexamethasone a… Folic Acid Immunoglobulins Lenograstim Leucovorin Levoleucovorin Mercaptopurine Methotrexate Muromonab-CD3 Rituximab Vincristine
Leukemia Leukemia, Lymph… Philadelphia Ch… Precursor Cell … Philadelphia Ch… Recurrent B Acu… Refractory B Ac…
Due to Competing Studies
-
NCT03145558
Details
2022-11-04
Interventional
2-
Doxorubicin Tirapazamine
Carcinoma Carcinoma, Hepa…
on hold by sponsor
-
NCT02574156
Details
2022-11-04
Interventional
3
[8 Refs]
500 
Insulin
Hyperglycemia
Finished
-
NCT02380118
Details
2022-11-04
Interventional
4167 
Haloperidol Haloperidol dec… Midazolam Olanzapine
Emergencies Psychomotor Agi… Acute Agitation…
Primary endpoint reached based on data projection from interim analysis.
-
NCT03430063
2017-003684-35
Details
2022-11-03
Interventional
228 
Cemiplimab Ipilimumab
Carcinoma, Non-… Advanced Non-Sm…
Business decision
All participants' tumors had PD-L1 expression levels of <50% at baseline. Therefore, the results do not present efficacy for participants with PD-L1 expression levels of ≥50% of tumor cells versus all participants.
NCT03035838
Details
2022-11-03
Interventional
10 
Aprepitant Fosaprepitant
Brain Injuries Brain Injuries,… Intracranial Hy… Wounds and Inju… Traumatic Brain…
Alternate study commenced using different drug
-
NCT02374853
Details
2022-11-03
Interventional
21037 
Vancomycin
Communicable Di… Infections Wound Infection INFECTION
the preliminary analysis of study result did not show significant benefit that was anticipate
-
NCT01244256
Details
2022-11-03
Interventional
2/3-
Beclomethasone Clotrimazole Gentamicins Miconazole
Folliculitis
-
-
NCT01229072
Details
2022-11-03
Interventional
2/3-
Calcium heparin Heparin
Kidney Failure,… Renal Insuffici… Renal Insuffici… Chronic Renal F…
-
-
NCT01228656
Details
2022-11-03
Interventional
240 
Mometasone Furo… Salicylates Salicylic Acid
Psoriasis Plaque Psoriasi…
-
-
NCT01086982
Details
2022-11-03
Interventional
1-
Octreotide
Acromegaly
-
-
NCT00717652
Details
2022-11-03
Interventional
2/3-
Tretinoin Triamcinolone
Melanosis Melasma
-
-
NCT04465916
Details
2022-11-02
Interventional
226 
Entecavir Tenofovir
Hepatitis Hepatitis B Hepatitis B, Ch…
DSMC reviewed results of 26 subjects. New randomizations were stopped. Already randomized subjects were followed up to W40.
-
NCT01666249
Details
2022-11-02
Interventional
3-
Antibodies Immunoglobulins Immunoglobulins…
Fetomaternal Tr… Hemorrhage Pregnancy; Feto…
Suspended for indetermined period.
-
NCT01558115
Details
2022-11-02
Interventional
48 
Denosumab
Hyperparathyroi… Hyperparathyroi… Primary Hyperpa…
Poor enrollment
Data was not collected and analyzed as per protocol due to study closing prematurely because of poor enrollment.
NCT03024437
Details
2022-11-01
Interventional
1/2-
Atezolizumab Bevacizumab Entinostat
Carcinoma, Rena… Kidney Neoplasm… Metastatic Canc… Renal Cancer
Major review underway
-
NCT00969397
Details
2022-11-01
Interventional
1/20 
Angiogenesis In…
Hemangioma, Cap… Port-Wine Stain Port Wine Stain
We have decided not to pursue the study
-