Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT02633293
Details
2022-12-02
Interventional
2/3243 
Treprostinil
Emphysema Hypertension Hypertension, P… Lung Diseases Lung Diseases, … Pulmonary Fibro… Combined Pulmon… Interstitial Lu… Pulmonary Hyper…
Inhaled treprostinil became commercially available in the US following its approval for PH-ILD
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NCT02229149
Details
2022-12-02
Interventional
233 
Capecitabine Docetaxel Paclitaxel Pertuzumab Trastuzumab Vinorelbine
Breast Neoplasm… Malignant Tumor…
per Sponsor request
-
NCT00591318
Details
2022-12-02
Interventional
1/212 
Ceftriaxone
Mental Disorder… Psychotic Disor… Schizophrenia Psychosis Schizoaffective…
Study was terminated after enrolling 12 patients due to poor enrollment rates
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NCT05633758
Details
2022-12-01
Interventional
20 
Metolazone
Heart Failure Acute Decompens…
no participants enrolled
-
NCT05260541
Details
2022-12-01
Interventional
211 
Pramoxine
Mental Disorder… Stress Disorder… Stress Disorder… Trauma and Stre… Mental Disorder Post Traumatic … Post-traumatic … Stress Disorder
No longer developing for this indication
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NCT04866056
Details
2022-12-01
Interventional
1/21 
Azacitidine
Myelodysplastic… Myeloproliferat… Neoplasms Preleukemia Primary Myelofi… Syndrome Myelofibrosis Myeloproliferat…
Corporate policy adjustments
-
NCT04402723
Details
2022-12-01
Interventional
18 
Cytarabine Daunorubicin
Leukemia, Myelo… Acute Myeloid L…
Corporate policy adjustments
-
NCT04076761
Details
2022-12-01
Interventional
28 
Trifluridine
Bile Duct Neopl… Cholangiocarcin… Bile Duct Cance…
Lack of Funding
-
NCT05387642
Details
2022-11-30
Interventional
20 
Pramoxine
Essential Tremo… Tremor
Sponsor no longer pursuing indication.
-
NCT03848403
Details
2022-11-30
Interventional
170 
Ixekizumab
Healthy
At the protocol-specified interim analysis, the sponsor decided to stop the trial.
At protocol-specified interim analysis, the sponsor decided to stop trial.
NCT02414750
Details
2022-11-30
Interventional
278 
Vemurafenib
Melanoma Metastatic Mela…
Slow accrual and changing treatment landscape
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NCT00858364
2007-005792-34
Details
2022-11-30
Interventional
32549 
Darbepoetin alf…
Anemia Carcinoma, Non-… Lung Neoplasms Cancer Lung Cancer Non-Small Cell …
-
-
NCT00823576
Details
2022-11-29
Interventional
460 
Ropivacaine
Pain, Postopera… Postoperative P…
-
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NCT00436748
Details
2022-11-29
Interventional
3116 
Darbepoetin alf…
Anemia Kidney Diseases Renal Insuffici… Chronic Kidney … Kidney Disease
FDA and EMA agreed that the information that had been submitted to date was acceptable to meet the requirements of the post-marketing commitment.
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NCT05456165
Details
2022-11-25
Interventional
21 
Atezolizumab Ipilimumab
Colonic Neoplas… Colorectal Neop… Neoplasms
terminated due to reprioritization
-
NCT03382925
Details
2022-11-25
Interventional
416 
Lidocaine Triamcinolone Triamcinolone A… Triamcinolone d… Triamcinolone h…
Asthenia Radiculopathy Cervical Radicu…
Not enough cervical interlaminar patients who meet criteria in order to meet recruitment goals.
Early termination leading to low enrollment which ended up being the greatest limitation.
NCT03011307
Details
2022-11-23
Interventional
2126 
Oxytocin
Pain, Postopera… Postoperative P…
Cessation of funding period prior to completion, due to slow recruitment during the pandemic.
The trial was terminated early because of depletion of funding. Power analysis was based on 120 subjects and only 90 were studied before termination of funding .
NCT03854227
Details
2022-11-22
Interventional
154 
Docetaxel
Neoplasms Advanced Solid … Metastatic Soli…
The study has been terminated based on a strategic evaluation within the current Pfizer oncology portfolio. This decision is not due to any safety concerns or requests from any regulatory authorities.
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NCT05481775
Details
2022-11-21
Interventional
2
[14 Refs]
0 
Immunomodulatin…
Carcinoma, Non-… Lung Neoplasms Efficacy and Sa… Locally Advance…
Clincal decision based on previous results
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NCT04847440
Details
2022-11-18
Interventional
240 
Tenofovir
Coinfection Hepatitis Hepatitis A Hepatitis B Hepatitis B, Ch… Hepatitis D Herpesviridae I… Virus Diseases
Terminated by the Sponsor
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