Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT04742348
Details
2023-02-13
Interventional
40 
Carbidopa Carbidopa, levo… Levodopa
Alcohol Drinkin…
COVID-19 and expiration of funding
-
NCT03546556
Details
2023-02-13
Interventional
110 
Alovudine Dideoxynucleosi…
Graft vs Host D… Graft Vs Host D…
Study terminated due to COVID-19 pandemic and not being able to perform PET/MR scans on participants.
-
NCT03762317
Details
2023-02-10
Interventional
410 
Clonidine
Neonatal Abstin… Syndrome
Study was initially suspended due to IND application and later terminated due to the difficulty of obtaining consent during COVID period
-
NCT03042546
Details
2023-02-10
Interventional
41 
Calcium
Fractures, Bone Tibial Fracture… Open tíbia Fra…
Study halted prematurely and will not resume; participants are no longer being examined or receiving intervention. Low enrollment and PI leaving institution
-
NCT04754334
Details
2023-02-09
Interventional
3346 
Insulin
Diabetes Mellit… Diabetes Mellit… T2DM (Type 2 Di…
The ORA-D-013-2 protocol was terminated based on the primary results analyzed at week 26 in the ORA-D-013-1 protocol.
-
NCT04606576
Details
2023-02-09
Interventional
3710 
Insulin Insulin, Globin…
Diabetes Mellit… Diabetes Mellit… Type 2 Diabetes…
ORA-D-013-1 was terminated based on the primary results analyzed at the end of the treatment, week 26.
-
NCT04154787
Details
2023-02-09
Interventional
237 
Rituximab
Glomerulonephri… Glomerulonephri… Kidney Diseases
Sponsor decision
-
NCT03844633
Details
2023-02-09
Interventional
449 
Medroxyprogeste… Medroxyprogeste…
Delay in Time t…
Because of insufficient enrollment, we closed the RCT and replaced it with an observational design
-
NCT02624479
Details
2023-02-09
Interventional
10 
Sodium thiosulf…
Healthy
Formulations could never be successfully produced
-
NCT00568672
2007-000512-82
Details
2023-02-09
Interventional
30 
Olanzapine
Depression Depressive Diso… Depressive Diso… Relapse Rate of… Safety of Olanz…
Withdrawn because of personal ressources before inclusion of the first patient
-
NCT05279235
Details
2023-02-08
Interventional
3290 
Favipiravir
COVID-19 Moderate to Sev…
Development strategy adjustment
-
NCT05156632
Details
2023-02-08
Interventional
30 
Aluminum Hydrox… Vaccines
COVID-19
The plan has changed
-
NCT04718961
2020-003448-96
Details
2023-02-08
Interventional
24 
Volixibat
Cholestasis Cholestasis, In… Pregnancy Compl… Intrahepatic Ch…
Due to company's assessment of enrollment feasibility.
-
NCT04290871
Details
2023-02-08
Interventional
2
[1 Refs]
0 
Nitric Oxide
COVID-19 Severe Acute Re… Syndrome Coronavirus Cov… SARS (Severe Ac…
The study will start to enroll patients soon
-
NCT04095858
NCT04976699
Details
2023-02-08
Interventional
311 
Methotrexate Tacrolimus
Graft vs Host D… Leukemia Myelodysplastic… Precursor Cell … Acute Graft Ver… Acute Lymphobla… Acute Myeloid L… Hematopoietic S…
Business Reasons
-
NCT03941496
Details
2023-02-08
Interventional
1/20 
Azacitidine
Tuberculosis Tuberculosis, P…
The study was halted prematurely due to Bristol-Myers Squibb's (BMS) decision to withdraw support for this study.
-
NCT03599518
Details
2023-02-08
Interventional
120 
Gefitinib
Carcinoma, Non-… Lung Neoplasms Non Small Cell …
This study was terminated based on a business decision by the Sponsor.
The sponsor decided to terminate the study at the end of the Dose Escalation part and the Dose Expansion part was not conducted.
NCT03504410
Details
2023-02-08
Interventional
3200 
Cytarabine Etoposide Fludarabine Mitoxantrone
Relapsed/Refrac…
Futile
-
NCT03236649
Details
2023-02-08
Interventional
389 
Sorafenib
Carcinoma Carcinoma, Hepa… Hepatocellular …
Because the clinical development plan has been changed.
-
NCT05363436
Details
2023-02-06
Interventional
4159 
Oxycodone
Opioid-Related … Opioid Abuse Opioid Misuse Pain
Recruitment Reorganzing
-