Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00369538
Details
2009-02-18
Interventional
4-
Hydrochlorothia… Losartan
Hypertension Kidney Diseases Kidney Failure,… Proteinuria End Stage Renal…
principle investigator moved, new investigators will join, insurance expired - project needs to be re-examined by an ethic committee
-
NCT00477802
Details
2009-02-16
Interventional
48 
Botulinum Toxin… Botulinum Toxin… abobotulinumtox…
Dyskinesias Parkinson Disea…
Intervention did not appear to be effective in most enrolled patients.
-
NCT00315601
Details
2009-02-13
Interventional
435 
Azithromycin Dimercaprol Telithromycin
Healthy
Sanofi-Aventis wanted the study terminated.
-
NCT00129870
Details
2009-02-13
Interventional
4180 
Oxaliplatin
Colorectal Neop… Colorectal Canc…
Unplanned interim analysis by DSMB indicated possible reduced response rate with the addition of Ca/Mg in pooled population. Further analysis pending.
-
NCT00668356
Details
2009-02-09
Interventional
2-
Didanosine
HIV Infections
questions of the benefit efficacy/risks of ddI during the meal not resolved
-
NCT00327093
Details
2009-02-09
Interventional
431 
Bevacizumab Cetuximab
Colorectal Neop… Neoplasm Metast… Colorectal Canc…
The scientific commitee decided to stop the inclusions and exploit the results.
-
NCT00190034
Details
2009-02-09
Interventional
4-
Acetylcysteine N-monoacetylcys…
Acute Kidney In… Cardiovascular … Renal Insuffici… Cardiopulmonary… Cardiovascular … Renal Insuffici…
opposite result
-
NCT00003067
Details
2009-02-09
Interventional
2
[1 Refs]
-
Aldesleukin
Central Nervous… Glioma Nervous System … Brain and Centr…
-
-
NCT00419549
Details
2009-01-29
Interventional
2/3371 
Valdecoxib
Pancreatitis ERCP
Because one of the drugs Valdecoxib was withdrawn due to safety concerns.
-
NCT00557921
2007-005891-15
Details
2009-01-28
Interventional
3-
Aspirin Clopidogrel Omeprazole
Acute Coronary … Coronary Artery… Infarction Myocardial Infa… Percutaneous Co…
Terminated by Sponsor
-
NCT00294749
2005-005959-17
Details
2009-01-27
Interventional
3-
Ciprofloxacin
Prostatic Neopl… Men Who Must Un…
-
-
NCT00203190
Details
2009-01-23
Interventional
4-
Topiramate
Cluster Headach… Headache
-
-
NCT00365222
Details
2009-01-22
Interventional
21 
Temozolomide
Glioblastoma Gliosarcoma
IRB Study Closure
-
NCT00298012
2005-001202-60
Details
2009-01-05
Interventional
4-
Methotrexate
Axial Spondyloa… Spondylarthriti… Spondylarthropa… Spondylitis Spondylitis, An…
-
-
NCT00397709
Details
2008-12-31
Interventional
4-
Isoniazid Rifampin
Infections Latent Tubercul… Tuberculosis
-
-
NCT00810706
Details
2008-12-18
Interventional
3
[2 Refs]
448 
Exemestane
Breast Neoplasm… Breast Cancer
Publication of MA17 results (similar trial in the extented adjuvant setting with letrozole)
-
NCT00235651
Details
2008-12-17
Interventional
3-
Amphotericin B Liposomal ampho…
Lung Diseases Lung Transplant…
study completed
-
NCT00177749
Details
2008-12-17
Interventional
4-
Posaconazole
Communicable Di… Infections Invasive Fungal… Mycoses Fungal Infectio…
Study is complete Analysis is complete
-
NCT00171119
Details
2008-12-17
Interventional
481 
Valsartan
Diabetes Mellit… Diabetic Nephro… Hypertension Diabetic Nephro…
-
-
NCT00324025
NCT00804635
Details
2008-12-12
Interventional
23 
Efungumab
Meningitis Meningitis, Cry… Cryptococcal Me…
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