Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01114750
2010-019098-14
Details
2010-10-05
Interventional
1-
Dextrans
Diabetes Mellit…
-
-
NCT00990444
2009-010660-42
Details
2010-10-05
Interventional
1/2-
Dextrans Insulin Insulin, Globin…
Diabetes Mellit…
-
-
NCT00830323
Details
2010-09-30
Interventional
2-
Amantadine Oseltamivir Zanamivir
Communicable Di… Infections Influenza, Huma… Influenza A Inf…
-
-
NCT00766870
2007-007025-51
Details
2010-09-29
Interventional
235 
Venlafaxine Hyd…
Depression Depressive Diso… Depressive Diso… Major Depressiv…
Study was previously paused and is now terminated
-
NCT00622245
2007-002551-17
Details
2010-09-27
Interventional
2166 
Quetiapine Fuma…
Bipolar Disorde… Depression Depressive Diso… Depression in P…
Human metabolite not yet covered sufficiently by nonclinical data
-
NCT00818701
Details
2010-09-24
Interventional
11 
Natriuretic Pep… Sildenafil Citr…
Heart Failure Renal Insuffici… Congestive Hear… Renal Dysfuncti…
started a NIH study that is competing for same subjects
-
NCT01204320
Details
2010-09-17
Interventional
4-
Albumin-Bound P… Paclitaxel
Angina Pectoris Angina, Stable Angina, Unstabl… Stable Angina Unstable Angina
-
-
NCT00630799
Details
2010-09-09
Interventional
320 
Leuprolide
Prostatic Neopl… Prostate Cancer
-
-
NCT00439569
Details
2010-09-08
Interventional
1/29 
4-phenylbutyric…
Atrophy Muscular Atroph… Muscular Atroph… Spinal Muscular… Spinal Muscular… Spinal Muscular…
Due to poor compliance with study drug administration.
The study was closed early due to poor study drug compliance. The sample size is therefore extremely limited.
NCT00133393
Details
2010-08-27
Interventional
2-
Pentoxifylline
Malaria Malaria, Falcip… Plasmodium Falc…
-
-
NCT00031473
NCT00001098
Details
2010-08-27
Interventional
3-
Ribavirin
Infections Pneumonia Respiratory Syn… Virus Diseases
-
-
NCT01187992
Details
2010-08-25
Interventional
3
[1 Refs]
290 
Atorvastatin
Acute Coronary … Coronary Artery… Coronary Diseas… Myocardial Isch… Syndrome
Interim analysis showed significant effect in favour of full-dose atorvastatin.
-
NCT00646425
Details
2010-08-19
Interventional
25 
Basiliximab
Uveitis Non-infectious …
-
-
NCT01049932
2009-017631-17
Details
2010-08-16
Interventional
1/20 
Rilpivirine
HIV Infections
Trial closed due to additional safety information.
-
NCT00704301
Details
2010-08-13
Interventional
4104 
Rivastigmine
Delirium
The study is prematurely terminated due to a safety issue
-
NCT00188552
Details
2010-08-13
Interventional
2-
Pentoxifylline Tocopherols Tocotrienols Vitamin E alpha-Tocophero…
Wounds and Inju…
May 2007: No annual renewal
-
NCT00998686
Details
2010-08-11
Interventional
3-
Sitagliptin Pho…
Diabetes Mellit… Diabetes Mellit… Type 2 Diabetes…
-
-
NCT00188669
Details
2010-08-11
Interventional
2-
Pentoxifylline Tocopherols Tocotrienols Vitamin E alpha-Tocophero…
Breast Neoplasm… Mastodynia
date: August 2006. No annual renewal
-
NCT00964834
Details
2010-08-10
Interventional
1-
Anti-Bacterial … Antibiotics, An… Doxycycline
Anthrax
Sister trial has SAE investigation underway - sponsor elected to withdraw as study expected to be repeated later
-
NCT00014651
Details
2010-08-10
Interventional
3-
Vapreotide
Pancreatic Neop… Postoperative C… Pancreatic Canc… Perioperative/P…
Teminated by the DSMB because there are no differences between the control group and the Vapreotide group
-