Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00855062
Details
2011-02-25
Interventional
1/273 
Minocycline
Cognitive Dysfu… HIV Infections HIV-associated …
The Neurologic AIDS Research Consortium Data Safety and Monitoring Board committee recommended to terminate the study early due to futility on 11/6/2009.
The estimated sample size was 100; however, due to early termination of the study, the total number of randomized participants was 73.
NCT00150085
Details
2011-02-18
Interventional
450 
Cyclosporine Cyclosporins
Tacrolimus-asso…
-
-
NCT00552578
Details
2011-02-17
Interventional
4
[1 Refs]
12 
Buprenorphine Buprenorphine, … Naloxone
Opioid-Related … Pain, Intractab… Opiate Addictio… Refractory Pain
"Tapering doses" protocol arm was not effective for treatment retention outcome.
-
NCT00637962
2007-000781-20
2007-000781-20
Details
2011-02-11
Interventional
123 
polysaccharide-…
Acquired Immuno… HIV Infections Immunologic Def… Acquired Immune…
IMP expired prior to completion of recruitment
-
NCT00473616
Details
2011-02-11
Interventional
1-
Irinotecan
Neoplasms Advanced Solid … Advanced Solid … Cancer
Termination of the study was made after a full review of program data and assessment of the current risk-benefit profile.
-
NCT00937664
Details
2011-02-07
Interventional
124 
Gemcitabine
Neoplasms Advanced Solid … Cancer Solid Tumors
Termination of the study was made after a full review of program data and assessment of the current risk-benefit profile.
-
NCT01140412
Details
2011-02-04
Interventional
114 
Fosamprenavir Maraviroc Ritonavir
Healthy
The trial prematurely terminated on November 1, 2010, due to healthy volunteer participants experiencing non-serious fosamprenavir-related skin rash.
-
NCT01034410
Details
2011-02-02
Interventional
2-
Cytarabine
Leukemia Leukemia, Myelo… Leukemia, Myelo… Acute Myeloid L…
-
-
NCT01286090
Details
2011-01-31
Interventional
44 
Cisapride
Diabetes Mellit… Gastroparesis
Sponsor request
-
NCT00252811
Details
2011-01-28
Interventional
2-
Gefitinib
Breast Neoplasm… Breast Cancer
-
-
NCT00233636
Details
2011-01-27
Interventional
2-
Gefitinib
Carcinoma Carcinoma, Squa… Head and Neck C…
-
-
NCT00233623
Details
2011-01-27
Interventional
2-
Fluorouracil Gefitinib Irinotecan Leucovorin
Colorectal Neop… Metastatic Colo…
-
-
NCT00405808
2006-001711-30
Details
2011-01-26
Interventional
32666 
Rimonabant
Obesity
EMEA recommendation to suspend Acomplia marketing authorisation
-
NCT00065117
Details
2011-01-26
Interventional
2-
Fluorouracil Leucovorin Oxaliplatin
Colorectal Neop… Neoplasm Metast… Neoplasms Metastases, Neo…
-
-
NCT01282879
Details
2011-01-25
Interventional
4
[2 Refs]
36 
Itraconazole
Graft vs Host D… Invasive Fungal…
In interim analysis, this study met the primary hypothesis.
-
NCT01281566
Details
2011-01-24
Interventional
48 
Cisapride
Premature Birth Infant, Newborn Infant, Prematu…
Sponsor request
-
NCT01281553
Details
2011-01-24
Interventional
46 
Cisapride
Gastroesophagea…
Sponsor request
-
NCT01281540
Details
2011-01-24
Interventional
420 
Cisapride
Gastroparesis
Sponsor request
-
NCT00577356
Details
2011-01-20
Interventional
26 
Docetaxel
Prostatic Neopl… Prostate Cancer
Safety reasons, though no safety issues arose.
the trial was closed prior to planned accrual of 30 patients due to an external report from the randomized trial of docetaxel and CG1940/CG8711 resulting in a higher incidence of deaths compared to docetaxel alone in metastatic prostate cancer.
NCT00003113
Details
2011-01-17
Interventional
26 
Cyclophosphamid… Etoposide Lomustine Procarbazine
Lymphoma Lymphoma, Non-H…
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