Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00082563
Details
2011-04-26
Interventional
214 
Azithromycin Chloroquine Chloroquine dip…
Malaria, Falcip…
-
-
NCT01074359
Details
2011-04-22
Interventional
2-
Tocopherylquino…
Neuromuscular D… Neuromuscular D…
Terminated for Commercial Reasons. There were no safety issues involved in the decision to terminate the study.
-
NCT00433017
Details
2011-04-21
Interventional
2/3255 
Ranibizumab Verteporfin
Choroidal Neova… Macular Degener… Neovascularizat…
Study was terminated based on the results of analyses performed as planned at Month 12.
-
NCT00352651
Details
2011-04-14
Interventional
2-
Pregabalin
Herpes Simplex Herpes Zoster Neuralgia Neuralgia, Post… Postherpetic Ne…
This study should be terminated as the study has been closed for years and the investigator has since retired. No records are available. Thank you, Marlene
-
NCT00162214
Details
2011-04-14
Interventional
1-
Dasatinib Ketoconazole
Neoplasms Tumors
-
-
NCT01133873
Details
2011-04-13
Interventional
4-
Dextropropoxyph… Levopropoxyphen…
Healthy
-
-
NCT00979667
Details
2011-04-11
Interventional
34 
Oseltamivir Zanamivir
Communicable Di… Infections Influenza, Huma… Orthomyxovirida… Respiratory Tra… Influenza Upper Respirato…
Decreased Influenza activity; thus decrease/no eligible patient to recruit
-
NCT00534456
Details
2011-04-08
Interventional
312 
Darbepoetin alf…
Anemia Cardiovascular … Heart Failure Ventricular Dys… Cardiovascular … Congestive Hear…
Study terminated
-
NCT00353808
Details
2011-04-07
Interventional
2112 
Reboxetine
Pain
This study has been terminated early as the esreboxetine development program is being discontinued. There are no safety or efficacy concerns.
-
NCT00930358
Details
2011-04-06
Interventional
4220 
Anesthetics
Colonoscopy Pro…
This study was stopped due to low inclusion
-
NCT01117376
Details
2011-03-31
Interventional
2-
Erythromycin Erythromycin Es… Erythromycin Et… Erythromycin st… Methylnaltrexon…
Gastroparesis
The study was prematurely terminated because of unavailibility of Methylnaltrexone in the region
-
NCT00124709
Details
2011-03-23
Interventional
41091 
Pimecrolimus
Dermatitis Dermatitis, Ato… Eczema Atopic Dermatit…
-
-
NCT00785811
Details
2011-03-16
Interventional
436 
N-Methylasparta…
Fatigue Muscular Fatigu…
Required by the investigator. The site could not recruit patients anymore.
-
NCT00049959
Details
2011-03-16
Interventional
3-
Verteporfin
Basal Cell Nevu… Carcinoma Carcinoma, Basa… Syndrome Basal Cell Carc… Gorlin Syndrome Nevoid Basal Ce…
-
-
NCT00000659
Details
2011-03-14
Interventional
2-
Zidovudine
AIDS-Related Co… HIV Infections
-
-
NCT00540280
Details
2011-03-08
Interventional
3-
Gemcitabine
Carcinoma, Non-…
Follow up only
-
NCT00480103
Details
2011-03-04
Interventional
3-
Mineral Oil
Healthy
INHERENT MODIFICATIONS NEEDED BEFORE PROCEEDING
-
NCT00774878
2008-000810-54
Details
2011-03-03
Interventional
218 
Fulvestrant
Breast Neoplasm…
Company decision to discontinue the AVE1642 development program, not due to any safety or efficacy concerns
-
NCT00514891
Details
2011-03-01
Interventional
4-
Vitamin A
Morbidity Mortality
Reccomended by DSMB after review of planned interim analyses.
-
NCT00316017
Details
2011-03-01
Interventional
3
[1 Refs]
895 
Dextrans
Shock Shock, Traumati… Wounds and Inju…
Futility & potential safety concern (increased early mortality in the HS/HSD arms for those with no PRBC in 1st 24 hr, post-randomization subgp)
The trial was stopped early for futility in the presence of a potential safety concern regarding increased mortality among patients receiving hypertonic solutions and no blood transfusions. This was no longer evident 6 hr after hospital admission.