Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01208740
Details
2011-05-24
Interventional
488 
Metformin
Infertility PCOS Prognosis for P…
Concerns about safety at the first interim analysis
-
NCT00287742
Details
2011-05-24
Interventional
333 
Risperidone
Alzheimer Disea… Delusions Dementia Hallucinations Alzheimer's Dis…
A decision was made to discontinue the study due to a change in the strategic direction of the company.
-
NCT00246597
Details
2011-05-19
Interventional
337 
Epoetin Alfa
Breast Neoplasm… Anemia Chemotherapy, A… Hemoglobins Quality of Life
Study stopped to avoid treating enrolled subjects to hemoglobin levels higher than those specified in current labeling.
-
NCT00306267
Details
2011-05-18
Interventional
261 
Epoetin Alfa
Anemia Cancer Epoetin Alfa
Study stopped as it would not address important survival concerns raised in other recently conducted clinical studies.
-
NCT00211120
Details
2011-05-18
Interventional
4
[1 Refs]
1432 
Epoetin Alfa
Renal Insuffici… Anemia
Stopped by the DSMB due to a trend toward more adverse events in the higher hemoglobin (Hb) arm and <5% chance that the study would show benefit for higher Hb.
-
NCT00312871
Details
2011-05-17
Interventional
4217 
Epoetin Alfa
Anemia Kidney Failure,… Renal Insuffici… Renal Insuffici… Renal Failure, …
Study was stopped due to restrictions in labeling for the subcutaneous route of administration of EPREX.
-
NCT00236327
Details
2011-05-17
Interventional
434 
Fentanyl
Cancer Pain Pain
Sponsor discontinued the study following the discovery of a number of incompletely sealed batches that were unusable.
-
NCT00076726
Details
2011-05-17
Interventional
2
[1 Refs]
44 
Infliximab
Arteritis Giant Cell Arte… Polymyalgia Rhe…
Interim analysis, infliximab did not reduce number of first relapses in GCA or cumulative glucocorticosteroid dosage
-
NCT00073372
Details
2011-05-17
Interventional
3
[1 Refs]
808 
Abciximab
Acute Disease Brain Ischemia Ischemic Stroke Stroke Cerebrovascular…
Based on the data and observed benefit-risk profile, the trial's independent oversight committee recommended that enrollment not resume.
-
NCT00796900
Details
2011-05-12
Interventional
2/3-
Dantrolene
Fever Hemorrhage Hyperthermia
organizationally not possible
-
NCT00470340
Details
2011-05-05
Interventional
3263 
Ethiodized Oil Gemcitabine Oxaliplatin
Carcinoma Carcinoma, Hepa… Fibrosis Liver Cirrhosis Liver Neoplasms Neoplasm Recurr… Neoplasms Recurrence
during the study
-
NCT00028067
Details
2011-05-04
Interventional
3-
Atazanavir Sulf… Nelfinavir
HIV Infections
-
-
NCT00193102
Details
2011-05-03
Interventional
2
[1 Refs]
-
Capecitabine Thalidomide
Breast Neoplasm… Breast Cancer
-
-
NCT00193024
Details
2011-05-03
Interventional
2
[1 Refs]
-
Docetaxel Epirubicin
Breast Neoplasm… Breast Cancer
-
-
NCT00216216
Details
2011-05-02
Interventional
2
[1 Refs]
43 
Pemetrexed
Lung Neoplasms Small Cell Lung… Small Cell Lung…
The results from the interim analysis were not favorable to continue this trial.
-
NCT00216138
Details
2011-05-02
Interventional
219 
Capecitabine Docetaxel
Carcinoma, Squa… Head and Neck N… Head and Neck C…
Interim analysis results did not meet criteria for second stage of trial
-
NCT00938353
2009-014376-22
Details
2011-04-29
Interventional
36 
Beclomethasone
Croup Laryngitis
possibility to discriminate the active drug from placebo
-
NCT00308594
Details
2011-04-28
Interventional
2-
Dexamethasone
Radiculopathy Cervical Radicu…
Study terminated due to withdrawl of participating co-investigators.
-
NCT00083486
Details
2011-04-27
Interventional
3-
Epoetin Alfa
Anemia
-
-
NCT00975663
Details
2011-04-26
Interventional
4-
Tacrolimus
Lung and Heart-…
-
-