Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00926354
Details
2011-06-21
Interventional
2-
Ammonium trichl…
Thrombocytopeni… Chemotherapy In…
Sponsor's considerations
-
NCT00706797
Details
2011-06-21
Interventional
4141 
Etanercept Methotrexate
Arthritis Arthritis, Rheu… Rheumatoid Arth…
-
Following early termination of the study, only disposition of randomized participants, description of demographic data on safety population, and safety analyses were performed.
NCT01010087
Details
2011-06-10
Interventional
259 
Oseltamivir
Influenza, Huma… Influenza A Vir…
Patient population no longer available.
-
NCT00802217
Details
2011-06-10
Interventional
1-
Capsaicin
Healthy
PK results demonstrated no systemic absorption
-
NCT00246298
Details
2011-06-10
Interventional
231 
Epoetin Alfa
Anemia HIV
OBI business decision not to complete any additional research in HIV.
-
NCT00210561
Details
2011-06-10
Interventional
422 
Acetaminophen Tramadol
Back Pain Low Back Pain
Study was stopped shortly after initiation due to change in strategic direction of the company; no safety concerns were observed that impacted this decision.
-
NCT01368887
Details
2011-06-08
Interventional
2-
Calcipotriene Niacin Niacinamide Nicotinic Acids
Psoriasis
Sponsor seeking additional financial support before starting the study
-
NCT01096329
Details
2011-06-08
Interventional
116 
Methyltestoster… Testosterone Testosterone 17… Testosterone en… Testosterone un…
Sexual Dysfunct… Hypoactive Sexu…
-
-
NCT00748787
2007-005019-25
Details
2011-06-08
Interventional
219 
Calcium polycar… Psyllium
Metabolic Syndr… Syndrome
It was very difficult to fulfill the inclusion criteria, therefore the expected time of inclusion was delayed so much time.
-
NCT00650637
Details
2011-06-08
Interventional
317 
Antidiarrheals Calcium Calcium Carbona… Calcium, Dietar… Lamivudine Lamivudine, zid… Loperamide Nelfinavir Zidovudine
Diarrhea
The study was prematurely discontinued due to administrative reasons on August 18, 2003. There were no safety concerns that led to the decision to terminate.
-
NCT00550004
Details
2011-06-08
Interventional
2-
Gemcitabine
Pancreatic Canc…
-
-
NCT00231634
Details
2011-06-08
Interventional
331 
Topiramate
Diabetes Mellit… Diabetes Mellit… Diabetes Mellit… Obesity
Program discontinued
-
NCT00231621
Details
2011-06-08
Interventional
3179 
Topiramate
Dyslipidemias Hyperlipidemias Hyperlipoprotei… Hypertriglyceri… Hyperlipidemia Obesity
The study was terminated prior to completion to focus on the development of a controlled release formulation.
-
NCT00034788
Details
2011-06-08
Interventional
384 
Becaplermin
Diabetic Foot Diabetic Neurop… Foot Ulcer Skin Ulcer Ulcer
Slow recruitment; Study did not address safety concern raised by European Medicines Agency
-
NCT00646087
Details
2011-06-06
Interventional
40 
Ketamine
Depressive Diso… Depressive Diso… Depressive Diso… Treatment Resis…
Pilot study determined that this study would not be feasible.
-
NCT00993421
Details
2011-06-03
Interventional
2343 
Metoprolol Sibutramine
Overweight Weight Loss Obesity
Clinical trial terminated due to results from recent nonclinical studies
-
NCT00539331
Details
2011-06-01
Interventional
16 
Carboplatin Cediranib Paclitaxel
Carcinoma, Non-…
-
-
NCT00348894
Details
2011-06-01
Interventional
2136 
Reboxetine
Peripheral Nerv… Pain
- Study was terminated due to insufficient clinical efficacy observed in previous studies conducted in postherpetic neuralgia.
-
NCT00333996
Details
2011-05-30
Interventional
2/35 
Dexamethasone
Iridocyclitis Uveitis Uveitis, Anteri… Anterior Uveiti…
-
-
NCT00326911
Details
2011-05-25
Interventional
261 
Bevacizumab Cetuximab Gemcitabine
Pancreatic Neop… Metastatic Panc…
The planned enrollment was 130 patients and the study was halted prematurely due to lack of efficacy in both arms. Enrolled patients continued treatment.
Accrual on the trial was stopped earlier than planned due to insufficient efficacy in both arms.