Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00244920
Details
2012-05-28
Interventional
20 
Androgen Antago… Bicalutamide Hormones Leuprolide Squalamine
Prostatic Neopl… Prostate Cancer
Sponsor withdrew drug.
-
NCT00243009
Details
2012-05-28
Interventional
21 
Cyclosporine Cyclosporins Fludarabine Fludarabine pho… Mycophenolic Ac…
Carcinoma, Rena… Kidney Neoplasm… Kidney Cancer
Due to a lack of a referal base, study was terminated.
-
NCT00240747
Details
2012-05-25
Interventional
3-
Quinupristin-da…
Bacterial Infec… Gram-Positive B…
-
-
NCT00006269
Details
2012-05-25
Interventional
389 
Irinotecan Octreotide
Colorectal Neop… Diarrhea Colorectal Canc…
-
-
NCT00249899
2005-004876-19
Details
2012-05-24
Interventional
3
[1 Refs]
649 
Atorvastatin Hydroxymethylgl… Rosuvastatin Ca… Simvastatin
Hypercholestero…
Overall profile of the compound does not offer significant clinical advantage to patients over currently available lipid lowering agents
-
NCT00237575
Details
2012-05-23
Interventional
3-
Gemcitabine Sargramostim
Urinary Bladder… Bladder Cancer
-
-
NCT00073970
Details
2012-05-23
Interventional
237 
Celecoxib
Prostatic Neopl… Prostate Cancer
Study stopped due to increased cardiovascular risks associated with Celebrex
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NCT00042315
Details
2012-05-23
Interventional
3-
Vinorelbine
Carcinoma, Non-… Lung Neoplasms Stage IIIb Non-… Stage IV Non-sm…
-
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NCT00042302
Details
2012-05-23
Interventional
3-
Albumin-Bound P… Carboplatin Paclitaxel
Carcinoma, Non-… Lung Neoplasms Stage IIIb Non-… Stage IV Non-sm…
-
-
NCT01124656
Details
2012-05-21
Interventional
326 
Azilsartan medo… Pioglitazone
Diabetes Mellit… Diabetes Mellit…
Formulation issues.
-
NCT00763347
Details
2012-05-21
Interventional
282 
Alogliptin
Diabetes Mellit…
Voluntarily terminated based on preliminary non-clinical findings.
-
NCT01601899
Details
2012-05-18
Interventional
460 
Efavirenz Lamivudine Stavudine Tenofovir
Metabolic Compl… Mitochondrial T…
DSMB decision to begin closeout process in view of April 2010 SA HAART guideline
-
NCT00807209
Details
2012-05-15
Interventional
23 
Bupivacaine Fentanyl
Pain, Postopera… Postoperative P…
Sponsor decision unrelated to safety
The study was terminated early due to Sponsor's decision, unrelated to safety. As there was only one patient in each group, no efficacy analyses were performed.
NCT00932464
Details
2012-05-14
Interventional
10 
Neratinib
Healthy
Study withdrawn as it no longer is deemed necessary per project status.
-
NCT00312546
Details
2012-05-14
Interventional
114 
Enfuvirtide Valproic Acid
HIV Infections
-
-
NCT00251511
Details
2012-05-11
Interventional
260 
Arsenic Trioxid…
Myelodysplastic… Preleukemia Syndrome Myelodysplastic…
Sponsor terminated trial
-
NCT01050491
Details
2012-05-10
Interventional
217 
Sitaxsentan
Airway Remodeli… Asthma Effect of Sitax…
sitaxentan is not commercialized anymore
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NCT00876850
Details
2012-05-09
Interventional
30 
Linezolid
Communicable Di… Infections Skin Diseases, … Soft Tissue Inf… Skin Structures…
Terminated
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NCT01103193
Details
2012-05-08
Interventional
44 
Remifentanil Sevoflurane
ASA Class I/II …
Need of change to the protocol. As the Principal Investigator has left the University Hospital Ghent end 2010, the change of protocol was never submitted.
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NCT00449813
Details
2012-05-07
Interventional
440 
Pantoprazole
Gastroesophagea… Non-Erosive Ref… Gastroesophagea… Non-erosive Ref…
Inclusion-rate does not seem feasible anymore to obtain te required number of patients before the end of the trial.
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