Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00726869
Details
2012-08-23
Interventional
128 
Elotuzumab
Multiple Myelom… Neoplasms, Plas…
Enrollment has been halted
-
NCT01416961
Details
2012-08-22
Interventional
10 
Cisplatin Etoposide Etoposide phosp…
Lung Neoplasms Lung Cancer
Neutron therapy has become unavailable
-
NCT01035346
Details
2012-08-21
Interventional
316 
Ibuprofen
Communicable Di… Infections Infection
-
Definitive conclusion could not be made due to early termination of study, due to low enrollment rate, and small number of enrolled participants.
NCT00015847
Details
2012-08-20
Interventional
225 
Imatinib Mesyla… Interferon-alph… Interferons
Leukemia Leukemia, Myelo… Leukemia, Myelo…
-
Early termination; 12 month follow-up was not carried out.
NCT01206907
Details
2012-08-17
Interventional
30 
Oxymorphone
Chronic Pain
The study is no longer required for the PREA for this product.
-
NCT01096095
Details
2012-08-17
Interventional
20 
4-phenylbutyric…
Ataxia Cerebellar Atax… Machado-Joseph … Spinocerebellar… Spinocerebellar… Spinocerebellar…
Regulatory authorities did not allow the entrance of the study drug in the country
-
NCT00385554
Details
2012-08-16
Interventional
10 
UC-781
HIV Infections
Study product is no longer being considered for further development.
-
NCT01563601
2011-005591-41
Details
2012-08-15
Interventional
30 
Carboplatin Etoposide Etoposide phosp… Obatoclax
Lung Neoplasms Small Cell Lung… Extensive-stage…
Business Decision
-
NCT00929162
Details
2012-08-07
Interventional
2120 
Carboplatin Paclitaxel
Carcinoma, Ovar… Hypersensitivit… Ovarian Neoplas… Patients With A…
Primary objective of the trial was not met and so there was no benefit in collecting further information
-
NCT00658333
Details
2012-08-07
Interventional
430 
Mycophenolic Ac…
Renal Transplan…
-
Due to the insufficient number of patients enrolled in the study, no conclusions can be made from the data.
NCT00427583
Details
2012-08-07
Interventional
2/311 
Imatinib Mesyla…
Nerve Sheath Ne… Neurofibrosarco… Malignant Perip…
stopped due to slow recruitment and no effect
-
NCT00409331
Details
2012-08-07
Interventional
23 
Amifostine
Head and Neck N… Head and Neck C…
Study terminated by Principal Investigator; no patients completed study.
-
NCT00108433
Details
2012-08-07
Interventional
361 
Cefazolin Linezolid Vancomycin
Bacteremia Bacterial Infec… Communicable Di… Gram-Positive B… Infections Sepsis
See Detailed Description
Efficacy results were not reported because the study was prematurely terminated.
NCT01352026
Details
2012-08-06
Interventional
20 
Metformin
Familial Primar… Hypertension Pulmonary Arter…
Several therapeutic have been developed making more difficult the eligibility of patients - Recruitment of new centers wasn't possible due to competing trials
-
NCT01274247
Details
2012-08-02
Interventional
1/221 
Benzocaine
Ankyloglossia Maternal Nipple… Neonatal Latch … Neonatal Tongue…
The study ethics committee recommended concluding the study for longer crying time with benzocaine and very short crying time in all participants.
-
NCT01270893
Details
2012-08-02
Interventional
20 
Nilotinib
Gastrointestina… Gastrointestina… Gastrointestina…
No particapnt recruitment.
-
NCT00324142
Details
2012-08-02
Interventional
20 
Tinidazole
Recurrence Vaginal Disease… Vaginosis, Bact… Recurrent Bacte…
Study Terminated Prematurely
-
NCT00976027
Details
2012-08-01
Interventional
39172 
Vaccines
Influenza, Huma… Influenza
No safety concerns, study terminated due to lack of primary endpoint cases in 2009-2010 Flu season (coincided with H1N1 Pandemic) Subjects followed per-protocol
The study was terminated due to lack of primary endpoint cases in 2009-2010 influenza season (coincided with the H1N1 Pandemic). There were no safety concerns; enrolled subjects were followed per-protocol.
NCT00800566
Details
2012-08-01
Interventional
10 
Clofarabine
Leukemia Leukemia, Lymph… Leukemia, Lymph… Chronic Lymphoc…
Sponsor terminated.
-
NCT00529282
Details
2012-08-01
Interventional
32 
Cefepime Ceftobiprole Ceftobiprole me… Vancomycin
Bacterial Infec… Communicable Di… Fever Gram-Positive B… Infections Neutropenia Pseudomonas Inf… Gram-positive B… Pseudomonas Inf…
Study discontinued due to administrative reasons unrelated to safety
No analysis was performed due to early termination of the study.