Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00991744
Details
2012-10-10
Interventional
3-
Cortisone Cytarabine Methylprednisol… Methylprednisol… Methylprednisol… Prednisolone Prednisolone ac… Prednisolone he… Prednisolone ph…
Leukemia Leukemia, Lymph… Precursor Cell … Acute Lymphobla…
Sterility problems in DepoCyte production
-
NCT00069992
Details
2012-10-10
Interventional
27 
Alemtuzumab Fludarabine
Leukemia Myelodysplastic… Myeloproliferat… Preleukemia Syndrome Chronic Myelopr…
Closed due to competing protocols
-
NCT00268372
Details
2012-10-04
Interventional
36 
Docetaxel Fluorouracil
Head and Neck N… Head and Neck C…
SWOG eliminated its head and neck committee
-
NCT01145755
Details
2012-10-03
Interventional
2131 
Duloxetine Hydr…
Depression Depressive Diso… Depressive Diso… Major Depressiv…
-
-
NCT01032837
Details
2012-10-02
Interventional
4102 
Oseltamivir
Influenza, Huma… Influenza
Study closed prematurely due to the end of the influenza (H1N1) 2009 pandemic
-
NCT00842829
2008-001841-24
Details
2012-10-01
Interventional
4330 
Fentanyl
Breakthrough Pa… Cancer Pain
Recruitment stopped at the end of the recruitment timeframe
-
NCT00248053
Details
2012-09-20
Interventional
20 
Curcumin
Adenomatous Pol… Colorectal Neop… Nasopharyngeal … Familial Adenom…
Subsequent data generated by our collaborators have shown efficacy with curcumin and quercetin in 5 patients in a non placebo controlled trial.
-
NCT00767494
Details
2012-09-19
Interventional
317 
Brinzolamide Travoprost
Glaucoma Hypertension Ocular Hyperten…
Project Cancelled
-
NCT00938236
Details
2012-09-17
Interventional
317 
Cyclosporine Cyclosporins
Respiratory Asp… Lung Transplant
Parent study CIS001 was completed
-
NCT01441206
Details
2012-09-14
Interventional
12 
Rifampin
Infection
Study to be redesigned.
-
NCT01150617
Details
2012-09-13
Interventional
446 
Hypoglycemic Ag… Insulin Insulin Glargin… Insulin, Globin… Insulin, Short-…
Diabetes Mellit… Diabetes Mellit… Peripheral Arte… Peripheral Vasc… Vascular Diseas… Peripheral Vasc… Type 2 Diabetes…
end-point reached
-
NCT00829049
Details
2012-09-12
Interventional
4165 
Adapalene Tazarotene
Acne Vulgaris
Study enrollment was terminated due to company decision before the target enrollment of 220 patients was reached.
Study enrollment was terminated due to company decision before the target enrollment of 220 patients was reached.
NCT01612377
Details
2012-09-11
Interventional
218 
Dipyridamole Prednisolone Prednisone
Arthritis Arthritis, Rheu… Rheumatoid Arth…
missed endpoint of meaningful clinical benefit, compared to prednisolone 2.7mg
-
NCT01135524
Details
2012-09-10
Interventional
3196 
Buprenorphine
Osteoarthritis
This study was terminated early for administrative reasons.
This study was terminated early for administrative reasons.
NCT01009593
2009-013435-38
Details
2012-09-10
Interventional
31035 
Sorafenib
Carcinoma Carcinoma, Hepa… Digestive Syste… Digestive Syste… Gastrointestina… Gastrointestina… Liver Diseases Liver Neoplasms Neoplasms Neoplasms by Hi… Neoplasms by Si… Neoplasms, Glan… Adenocarcinoma Hepatocellular … Hepatocellular …
See termination reason in detailed description
-
NCT00312221
Details
2012-09-10
Interventional
3418 
Buprenorphine Oxycodone
Osteoarthritis
terminated early for administrative reasons unrelated to safety or efficacy
This study was terminated early for administrative reasons not related to safety or efficacy. Low enrollment at termination led to reduced power.
NCT00664105
Details
2012-09-07
Interventional
263 
Carboplatin Docetaxel
Carcinoma, Non-… Lung Neoplasms Lung Cancer
Treatment became standard.
Outcome measure #4, "Number of participants with AEs by grade", will not match the total number of participants in this study. Some participants have multiple events in one or more grade designations or some participants have no events at all.
NCT00058747
NCT00070395
Details
2012-09-07
Interventional
2-
Imatinib Mesyla…
Leukemia Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo…
Business decision of the sponsor
-
NCT00582738
Details
2012-09-06
Interventional
243 
Everolimus
Disease Progres… Fibrosis Hepatitis Hepatitis A Hepatitis C Infections Recurrence Virus Diseases Recurrent Hepat…
-
-
NCT01223053
Details
2012-09-05
Interventional
30 
Ketoprofen
Soft Tissue Inj… Sprain
Revised Development Program
-