Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00528008
Details
2012-11-09
Interventional
3268 
Chlorhexidine Chlorhexidine g… Povidone Povidone-Iodine
Communicable Di… Infections Wound Infection Wounds and Inju…
Study was stopped following interim analysis.
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NCT00795587
2008-004979-21
Details
2012-11-08
Interventional
43 
Mannitol
Brain Injuries Brain Injuries,… Hypertension Intracranial Hy… Traumatic Brain…
evolution of patient's care allows no more recruitment
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NCT01604863
Details
2012-11-01
Interventional
1-
Carboplatin Docetaxel Etoposide Paclitaxel
Neoplasms Cancer
Study suspended prior to enrollment
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NCT00656422
Details
2012-11-01
Interventional
366 
Insulin Insulin Detemir Insulin, Globin…
Diabetes Mellit… Diabetes Mellit… Weight Gain Diabetes Obesity
-
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NCT00714376
Details
2012-10-31
Interventional
26 
Docetaxel
Prostatic Neopl… Prostate Cancer
Prematurely terminated due to financial considerations
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NCT00698789
Details
2012-10-30
Interventional
248 
Metformin
Diabetes Mellit… Type 2 Diabetes
Study ended after diabetes development plan review. .
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NCT01151137
2010-019791-73
Details
2012-10-26
Interventional
3
[1 Refs]
3236 
Dronedarone
Atrial Fibrilla…
The study was stopped because of safety concerns
Given that the study was prematurely discontinued after 3236 patients were randomized (30% of the initial planned number), p-values were provided for information without any adjustment for multiplicity.
NCT00741611
Details
2012-10-26
Interventional
344 
Anti-Arrhythmia…
Atrial Fibrilla… Paroxysmal Atri…
Business reasons
Due to the study's early termination and enrollment of only 7 randomized patients, predefined study endpoints were not evaluable. Treated patients were followed through 12 months postprocedure and data were summarized where possible.
NCT01202058
Details
2012-10-25
Interventional
3156 
Everolimus Sirolimus
Coronary Artery… Coronary Diseas… Myocardial Isch… Atherosclerotic…
The NEVO™ stent will not be commercialized. Cordis decided to close the study after 1 years. This decision took the absence of safety signals into account.
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NCT00714883
Details
2012-10-25
Interventional
23 
Sirolimus
Coronary Diseas…
The NEVO™ stent will not be commercialized. Cordis decided to close the study after 3 years. This decision took the absence of safety signals into account.
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NCT00211562
Details
2012-10-24
Interventional
320 
Olanzapine Vitamin E
Schizophrenia
-
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NCT01244269
Details
2012-10-22
Interventional
46 
Methylphenidate
Parkinson Disea… Parkinson's Dis…
Inadequate enrolment, protocol too challenging for participants, lack of observable benefit after analysis of 6 patients.
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NCT00503971
Details
2012-10-22
Interventional
1/250 
Erlotinib Hydro… Vorinostat
Carcinoma, Non-… Lung Neoplasms Non-small Cell …
-
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NCT00387010
Details
2012-10-22
Interventional
3
[1 Refs]
218 
Fentanyl
Breakthrough Pa… Chronic Pain Pain
The sponsor felt enough information was available for the exploratory assessment of the effect of treatment with FBT on pain anxiety
This study was terminated early. Additional research is recommended to develop a valid measure of anxiety, specifically related to breakthrough pain.
NCT00206765
Details
2012-10-22
Interventional
2-
Paroxetine Risperidone
Depressive Diso… Depressive Diso… Panic Disorder Major Depressiv…
-
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NCT00555321
Details
2012-10-18
Interventional
2260 
Abatacept Basiliximab Mycophenolic Ac… Tacrolimus
Immunosuppressi…
-
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NCT00313261
Details
2012-10-17
Interventional
2-
Clevudine
Hepatitis Hepatitis B
-
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NCT00121953
Details
2012-10-17
Interventional
2/30 
Rosiglitazone
Endometriosis
Due to the recent meta-analysis about CV adverse effects.
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NCT00115661
Details
2012-10-17
Interventional
2-
Rosiglitazone
Endometriosis
Due to the meta-analysis about CV adverse effects of rosiglitazone.
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NCT01352039
Details
2012-10-16
Interventional
3544 
Calcium heparin Heparin
Fractures, Bone Hip Fractures Hip Fracture Su…
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