Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00002819
Details
2013-04-11
Interventional
3-
Carboplatin Cyclophosphamid… Mitoxantrone Paclitaxel
Carcinoma, Ovar… Ovarian Neoplas… Ovarian Cancer
-
-
NCT01329809
Details
2013-04-10
Interventional
22 
Molgramostim Sargramostim
Carcinoma Colorectal Neop… Vaccinia Colorectal Carc…
-
-
NCT00054405
NCT00065494
Details
2013-04-09
Interventional
140 
Aldesleukin Interleukin-12 Interleukin-2
Neuroblastoma Recurrent Neuro…
Administratively complete.
-
NCT00053950
Details
2013-04-09
Interventional
142 
NSC 366140
Neuroblastoma Disseminated Ne… Recurrent Neuro…
Administratively complete.
-
NCT00467896
Details
2013-04-04
Interventional
262 
Iloprost
Hypertension Hypertension, P… Pulmonary Hyper…
Sponsor's decision
Study was terminated early due to the discontinuation of the I-neb Power Disc-15 development program.
NCT01820962
Details
2013-03-29
Interventional
3212 
Heparin
Bacteremia Catheter-Relate… Hematologic Neo… Thrombosis Hematological M…
Because the inclusion rate was lower than expected.
-
NCT00216281
Details
2013-03-26
Interventional
3126 
Atomoxetine Hyd… Clozapine
Schizophrenia
-
-
NCT01368536
Details
2013-03-21
Interventional
4975 
Amlodipine Chlorthalidone
Diabetes Mellit… Hypertension Diabetes Stage 2 Hyperte…
Based on results from an ALTITUDE study interim analysis, testing aliskiren concomitantly with an ACE inhibitor or ARB, in diabetics with renal impairment
-
NCT00091195
NCT01645670
NCT01660282
Details
2013-03-19
Interventional
251 
Romidepsin
Carcinoma, Ovar… Peritoneal Neop… Recurrence Primary Periton… Recurrent Ovari…
Administratively complete.
-
NCT01179490
Details
2013-03-18
Interventional
25 
Prednisolone
Multiple Myelom… Neoplasms, Plas…
-
-
NCT01088620
2009-014677-41
Details
2013-03-14
Interventional
2-
Panitumumab Pemetrexed
Carcinoma, Non-…
the DSMB stopped the trial due to unacceptable side effects in the experimental arm which has not yet been verified
-
NCT01612078
Details
2013-03-13
Interventional
325 
Droxidopa
Hypotension Hypotension, Or… Orthostatic Hyp…
-
-
NCT00634933
NCT01616706
Details
2013-03-11
Interventional
2222 
Methylprednisol… Methylprednisol… Methylprednisol… Prednisolone Prednisolone ac… Prednisolone he… Prednisolone ph… Prednisone
Arthritis Arthritis, Rheu…
The study was terminated on 21 June 2010 due to results not meeting the primary endpoint. No safety reasons contributed to the termination of the study.
As the results of the primary analysis did not meet the predefined efficacy criteria, the development of TRU-015 was discontinued.
NCT00937482
Details
2013-03-08
Interventional
118 
Cediranib
Brain Neoplasms Breast Neoplasm… Breast Neoplasm… Carcinoma, Non-… Carcinoma, Rena… Colonic Neoplas… Lung Neoplasms Rectal Neoplasm… Male Breast Can… Stage IV Breast… Stage IV Melano… Stage IV Non-sm… Stage IV Renal … Stage IVA Colon… Stage IVA Recta… Stage IVB Colon… Stage IVB Recta… Tumors Metastat…
Administratively complete.
-
NCT00138424
Details
2013-03-08
Interventional
1/222 
Cidofovir
Kidney Diseases BK Virus (Nephr…
-
The study closed early due to failure to enroll in a timely manner.
NCT01602822
Details
2013-03-07
Interventional
411 
Atazanavir Sulf… Emtricitabine Emtricitabine, … Ritonavir Tenofovir
HIV
Grade 3 elevation in liver function tests
-
NCT01094613
Details
2013-03-07
Interventional
1/270 
Mercaptopurine
Crohn Disease Crohn's Disease
Sponsor withdrew support of study due to reorganization and project prioritization
-
NCT00619346
Details
2013-03-07
Interventional
1100 
Pafuramidine
Healthy
FDA Full Clinical Hold due to safety concerns, as of 12/21/07
-
NCT00302341
Details
2013-03-07
Interventional
348 
Pafuramidine Sulfamethoxazol… Trimethoprim Trimethoprim, S…
Lung Diseases, … Pneumonia Pneumonia, Pneu… HIV Infections Pneumocystis Ca… Pneumonia, Inte… Pneumonia, Pneu…
FDA Clinical Hold as of 12/21/07 due to safety concerns
-
NCT00067041
Details
2013-03-07
Interventional
2/3-
Treprostinil
Chronic Limb-Th… Ischemia Peripheral Arte… Peripheral Vasc… Vascular Diseas… Peripheral Vasc…
-
-