Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01163799
Details
2013-05-03
Interventional
19 
Alefacept
Renal Insuffici… Transplant; Fai…
Noted increased risks, greater than expected for standard of care therapy.
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NCT00650949
Details
2013-05-03
Interventional
1/220 
Carboplatin
Glioblastoma Glioblastoma Mu…
Strategic
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NCT00541333
Details
2013-05-03
Interventional
115 
Glatiramer Acet…
Macular Degener… Dry Age Related…
Reviewing data
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NCT00089141
Details
2013-05-03
Interventional
3
[1 Refs]
151 
Mycophenolic Ac…
Bronchiolitis O… Graft vs Host D… Cancer
Low probability of positive outcome
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NCT00004856
Details
2013-05-03
Interventional
240 
Trastuzumab
Carcinoma Carcinoma, Tran… Kidney Neoplasm… Recurrence Ureteral Neopla… Urethral Neopla… Urinary Bladder… Distal Urethral… Metastatic Tran… Proximal Urethr… Recurrent Bladd… Recurrent Trans… Recurrent Ureth… Stage IV Bladde… Transitional Ce… Urethral Cancer…
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NCT00000419
Details
2013-05-03
Interventional
3
[1 Refs]
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Estrogens, Conj… Medroxyprogeste…
Lupus Erythemat… Systemic Lupus …
-
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NCT01528501
Details
2013-05-01
Interventional
2-
Panobinostat
Stomach Neoplas… Metastatic Gast…
medical/ethical reasons
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NCT00846521
Details
2013-05-01
Interventional
423 
Acarbose
Cardiovascular … Glucose Intoler… Insulin Resista… Obesity Pediatric Obesi… Vascular Diseas… Cardiovascular … Impaired Glucos…
-
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NCT00043212
Details
2013-05-01
Interventional
30 
Immunomodulatin…
Prostatic Neopl… Prostate Cancer
Redirection of company goals
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NCT00005073
Details
2013-05-01
Interventional
3
[1 Refs]
544 
Zoledronic Acid
Prostatic Neopl… Prostate Cancer
-
-
NCT01315496
Details
2013-04-30
Interventional
3-
Antibodies Immunoglobulin … Immunoglobulins Immunoglobulins…
Sepsis Shock Shock, Septic Toxemia Septic Shock Severe Sepsis
-
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NCT01032122
Details
2013-04-25
Interventional
19 
Rituximab
Melanoma Metastatic Mela…
the only reason is that recruitment was not sufficient to meet the planned patient numbers, because complete remissions are still infrequent.
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NCT00766506
2008-000529-20
Details
2013-04-25
Interventional
4108 
Fentanyl Morphine
Pain, Postopera…
Product class one recall
Study was temporarily stopped due to an issue with a batch of drug outside the study and later permanently stopped.
NCT01187888
2008-007520-26
Details
2013-04-24
Interventional
344 
Rasagiline
Paralysis Supranuclear Pa… Progressive Sup…
IMP used off label by phys. in pat. with PSP. Thus no more eligible patients were available for the study(pre-treatm.with Rasagiline=exclusion criterion
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NCT00708942
Details
2013-04-24
Interventional
283 
Aminolevulinic …
Carcinoma in Si… Neoplasms Uterine Cervica… Cervical Intrae…
Slow recruitment, study stopped with only 13 of 70 patients included in second part of the study
Slow recruitment lead to early terminaiton of the second part of the trial, including arms 4 and 5, after enrolment of 13 patients. No formal statistical analysis conducted on this part of the data.
NCT01212965
Details
2013-04-23
Interventional
15 
Selenium
Congenital Abno… Lymphangioma Lymphatic Abnor… Lymphatic Malfo…
The investigators chose to terminate the study due to participant attrition. Of the limited data evaluable, none of the patients experienced adverse events.
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NCT00283309
Details
2013-04-23
Interventional
420 
Memantine Riluzole
Memory Disorder… Memory Deficit Mood
Study finished enrollment but data was never sent for publishing.
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NCT00577395
Details
2013-04-22
Interventional
413 
Risedronic Acid
Osteoporosis
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NOTE: The study was terminated early (after 5 months), prior to acquiring any efficacy endpoints; consequently, NO subject efficacy analyses were performed
NCT00035581
Details
2013-04-17
Interventional
216 
Poly I-C poly(I).poly(c1…
HIV Infections HIV Seropositiv… HIV Infection
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NCT01184196
Details
2013-04-16
Interventional
455 
Povidone Povidone-Iodine
Arthroplasty, K… Replacement, To… Total Knee Repl…
ChloroPrep Wipes no longer available
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