Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00488774
NCT01842152
2006-003397-94
Details
2013-06-14
Interventional
2/3291 
Antibodies, Mon… Golimumab
Colitis Colitis, Ulcera… Ulcer
Protocol was cancelled by company based on overall efficacy, no safety concern
Data collection was not considered complete for primary outcome measure because study was terminated prematurely.
NCT01091051
Details
2013-06-11
Interventional
333 
Ustekinumab
Psoriasis Palmo-Plantar P… Palmo-Plantar P…
Manufacturer ceased to produce vials used for this study.
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NCT00555464
Details
2013-06-11
Interventional
28 
Methylprednisol… Methylprednisol… Methylprednisol… Prednisolone Prednisolone ac… Prednisolone he… Prednisolone ph… Prednisone Vincristine
Hemangioma
The introduction of oral propranolol as a highly efficacious agent for infantile hemangiomas
The limitations of this trial include early termination of enrollment leading to small numbers of subjects analyzed.
NCT01095094
NCT00792987
Details
2013-06-10
Interventional
219 
Lopinavir Ritonavir
Astrocytoma Brain Neoplasms Ependymoma Glioblastoma Glioma Gliosarcoma Oligodendroglio… Anaplastic Astr… Anaplastic Epen… Anaplastic Olig… Brain Stem Glio… Brain Tumor Giant Cell Glio… Mixed Glioma
Study did not meet its primary objective
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NCT00687388
Details
2013-06-10
Interventional
40 
Adrenergic alph… Alfuzosin Celecoxib Doxazosin Prazosin Tamsulosin Terazosin
Hyperplasia Inflammation Prostatic Hyper… Benign Prostati…
in order to prepare a new clinical trial to evaluate with pathological change
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NCT00006096
Details
2013-06-10
Interventional
3-
Cisplatin
Vulvar Neoplasm… Vulvar Cancer
-
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NCT00003382
Details
2013-06-10
Interventional
1
[1 Refs]
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Gemcitabine Topotecan
Carcinoma, Ovar… Fallopian Tube … Ovarian Neoplas… Fallopian Tube … Ovarian Cancer Primary Periton…
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NCT00003380
Details
2013-06-10
Interventional
1-
Doxorubicin Etoposide Liposomal doxor…
Fallopian Tube … Fallopian Tube … Ovarian Cancer Primary Periton…
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NCT00003179
Details
2013-06-10
Interventional
2
[2 Refs]
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Medroxyprogeste… Medroxyprogeste…
Endometrial Neo… Endometrial Can…
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NCT00002478
Details
2013-06-10
Interventional
2
[3 Refs]
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Etoposide
Uterine Cervica… Cervical Cancer Ovarian Cancer
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NCT00793858
Details
2013-06-07
Interventional
40 
Ciclesonide
Rhinitis Rhinitis, Aller… Allergic Rhinit…
Cost prohibitive and company withdrew support.
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NCT00307099
Details
2013-06-07
Interventional
3-
Anti-Bacterial … Meropenem
Bacterial Infec… Bacterial Infec…
-
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NCT01238146
Details
2013-06-06
Interventional
1/20 
Bendamustine Hy… Obatoclax Rituximab
Lymphoma Lymphoma, B-Cel… Lymphoma, B-Cel… Lymphoma, Folli… Lymphoma, Mantl… Lymphoma, Non-H… Recurrence Extranodal Marg… Nodal Marginal … Recurrent Grade… Recurrent Grade… Recurrent Mantl… Recurrent Margi… Splenic Margina…
No patients accrued.
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NCT00303836
NCT00255203
Details
2013-06-06
Interventional
258 
Aldesleukin Cyclophosphamid… Fludarabine Fludarabine pho… Freund's Adjuva… Interleukin-2
Melanoma Recurrent Melan… Stage IV Melano…
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NCT00087269
Details
2013-06-06
Interventional
2110 
Erlotinib Hydro…
Carcinoma, Non-… Lung Neoplasms Stage IA Non-sm… Stage IB Non-sm… Stage IIA Non-s… Stage IIB Non-s… Stage IIIA Non-…
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NCT00009984
Details
2013-06-06
Interventional
270 
Fludarabine Fludarabine pho… Thalidomide
Leukemia Leukemia, Lymph… Leukemia, Lymph… Recurrent Small… Refractory Chro…
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NCT00091078
Details
2013-06-05
Interventional
296 
Imatinib Mesyla… Oblimersen
Gastrointestina… Gastrointestina…
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NCT01351038
Details
2013-06-04
Interventional
2-
Capecitabine Epirubicin Oxaliplatin Panitumumab
Adenocarcinoma KRAS Wild Type Resectable Type…
REAL trial showed a significant difference in OS for reduced EOX and standard EOX
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NCT00406874
Details
2013-06-04
Interventional
26 
Folic Acid
Infertility
reports indicating that increased folic acid intake may increase colin cancer
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NCT00103272
Details
2013-06-04
Interventional
174 
Bortezomib
Hypereosinophil… Immunoblastic L… Leukemia Leukemia, Basop… Leukemia, Eosin… Leukemia, Eryth… Leukemia, Lymph… Leukemia, Megak… Leukemia, Monoc… Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo… Leukemia, T-Cel… Leukemia-Lympho… Lymphoma Lymphoma, B-Cel… Lymphoma, B-Cel… Lymphoma, Folli… Lymphoma, Large… Lymphoma, Large… Lymphoma, Mantl… Lymphoma, Non-H… Lymphoma, T-Cel… Lymphoma, T-Cel… Mycoses Mycosis Fungoid… Precursor Cell … Recurrence Sezary Syndrome Waldenstrom Mac… Adult Acute Bas… Adult Acute Eos… Adult Acute Meg… Adult Acute Min… Adult Acute Mon… Adult Acute Mon… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Erythrole… Adult Pure Eryt… Anaplastic Larg… Angioimmunoblas… Extranodal Marg… Nodal Marginal … Recurrent Adult… Recurrent Adult… Recurrent Adult… Recurrent Adult… Recurrent Cutan… Recurrent Grade… Recurrent Grade… Recurrent Grade… Recurrent Mantl… Recurrent Margi… Recurrent Mycos… Recurrent Small… Refractory Chro… Small Intestine… Splenic Margina… Waldenström Ma…
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