Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

Filter:

Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
Free Text
Annotations

7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01060293
Details
2013-09-11
Interventional
4161 
Dopamine Furosemide
Heart Failure Acute Decompens…
Safety issues in the LDFD-group (higher heart rate with dopamine)
-
NCT01701375
Details
2013-09-09
Interventional
12 
Palbociclib
Acute Disease Leukemia Myelodysplastic… Preleukemia High-Risk Myelo… Refractory Acut… Relapsed Acute …
Material sponsor withdrew support
-
NCT01031628
Details
2013-09-09
Interventional
35 
Imatinib Mesyla…
Gastrointestina…
Lack of feasibility secondary to slow accrual
A decision was made to discontinue the SARC019 trial effective March 3, 2011, due to lack of feasibility secondary to slow accrual. Due to early termination of the study, no patients were analyzed.
NCT00456339
Details
2013-09-05
Interventional
44 
Amoxicillin Amoxicillin-Pot… Clavulanic Acid Clavulanic Acid… Prednisolone
Apnea Sleep Apnea Syn… Sleep Apnea, Ob… Syndrome Obstructive Sle…
Problems recruiting; patient relapse following treatment
-
NCT00376337
Details
2013-09-05
Interventional
217 
Antifungal Agen… Clotrimazole Micafungin Miconazole
Aspergillosis Invasive Asperg…
Study was stopped due to difficulties in recruitment and changes in standard care for invasive aspergillosis
-
NCT00003847
Details
2013-09-05
Interventional
2
[1 Refs]
36 
Doxorubicin Liposomal doxor… Vincristine
Lung Neoplasms Small Cell Lung… Lung Cancer
-
-
NCT01130376
Details
2013-09-04
Interventional
112 
Aldesleukin Hormones Interleukin-2 Sargramostim
Infections HIV-1 Infection
Data from the 12 patients recruited has now been analysed, and it has been determined that it is sufficient to meet the study objectives.
-
NCT00215852
Details
2013-09-04
Interventional
217 
Interferon-alph…
HIV Infections
-
-
NCT00109772
Details
2013-08-28
Interventional
2184 
Lenalidomide
Complex Regiona… Reflex Sympathe… Somatoform Diso… Syndrome Complex Regiona…
Interim analysis showed the primary outcome was not reached
-
NCT01404117
Details
2013-08-27
Interventional
20 
(T,G)-A-L Glatiramer Acet… Interferon-beta Interferons
Multiple Sclero… Relapsing Multi…
Study is being redesigned
-
NCT00738972
NCT00621127
Details
2013-08-26
Interventional
312 
Ezetimibe Pravastatin Simvastatin Valsartan
Hypertrophy Hypertrophy, Le… Hypertension
Study terminated early due to sample size, not possible to perform further statistical analysis.
This study was terminated early and due to sample size it was not possible to perform further statistical analyses.
NCT00862082
NCT00838604
Details
2013-08-23
Interventional
1/214 
Nitrogen Mustar… Sorafenib
Carcinoma Carcinoma, Hepa… Hepatocellular …
PR104 plus sorafenib was poorly tolerated in patients with advanced HCC
Early termination leading to small numbers of subjects analyzed. Phase II part of study never initiated.
NCT00414466
Details
2013-08-23
Interventional
2254 
Gabapentin
Pain, Intractab… Chronic Intract…
Study closed and subject follow-up completed following analysis of blinded study data.
-
NCT01504386
Details
2013-08-22
Interventional
470 
Ropivacaine
Hysterectomy
Due to local restructering, further recruting was not possible
-
NCT00241371
Details
2013-08-13
Interventional
28 
Clofarabine
Multiple Myelom… Neoplasms, Plas…
No response seen in patients
-
NCT00803283
Details
2013-08-12
Interventional
32 
Morphine
Cancer Pain
-
This study had inadequate number of participants. 'The study was terminated early and the data for efficacy assessments were missing.
NCT00732940
Details
2013-08-07
Interventional
256 
Belimumab
Lupus Erythemat… Systemic Lupus …
Sponsor terminated study for business reasons.
-
NCT00328926
Details
2013-08-07
Interventional
411 
Chorionic Gonad… Follicle Stimul… Hormones
Hypogonadism Hypogonadotropi…
Please see "Purpose" statement
-
NCT01804673
2005-004087-24
Details
2013-08-05
Interventional
4174 
Fentanyl
Pain, Postopera… Postoperative P…
The study was prematurely discontinued since study medication was no longer available.
The study was prematurely discontinued after enrolling 184 of 200 planned participants because the study medication was no longer available.
NCT00033306
Details
2013-08-05
Interventional
22 
Irinotecan
Colorectal Neop… Colorectal Canc…
-
-