Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00058461
Details
2013-10-08
Interventional
2-
Carboplatin Cytarabine Etoposide Ifosfamide Methotrexate Rituximab
Burkitt Lymphom… Leukemia Leukemia, Lymph… Lymphoma Lymphoma, Large… Lymphoma, Large… Lymphoma, Non-H… Plasmablastic L… Precursor Cell … Recurrence B-cell Childhoo… Childhood Burki… Childhood Diffu… Childhood Immun… L3 Childhood Ac… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child…
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NCT01302106
2009-012755-23
Details
2013-10-01
Interventional
20 
Clofarabine
Myelodysplastic… Preleukemia Syndrome
For increased induction mortality in older patients due to specific combinations of drugs, other clinical factors such as patient age and comorbidities.
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NCT01135290
Details
2013-10-01
Interventional
10 
Petrolatum
Chemical Peel
Business decision, formulation will not be pursued.
-
NCT00536107
Details
2013-10-01
Interventional
414 
Docetaxel Gefitinib
Carcinoma, Non-…
-
This study was terminated early because the purpose of this study had been fulfilled by other supporting data, and due to small number of patients enrolled (14 patients).
NCT01705340
Details
2013-09-30
Interventional
160 
Lapatinib Trastuzumab
Breast Neoplasm… Breast Neoplasm… Esophageal Neop… Recurrence Stomach Neoplas… Adenocarcinoma … HER2-positive B… Male Breast Can… Recurrent Breas… Recurrent Esoph… Recurrent Gastr… Stage IIIC Brea… Stage IIIC Esop… Stage IIIC Gast… Stage IV Breast… Stage IV Esopha… Stage IV Gastri…
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NCT01208441
Details
2013-09-30
Interventional
128 
2,2-dimethyl-N-… Letrozole
Breast Neoplasm… Estrogen Recept… HER2-negative B… Progesterone Re… Stage II Breast… Stage IIIA Brea…
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NCT01192763
Details
2013-09-30
Interventional
130 
2,2-dimethyl-N-…
Pancreatic Neop… Adenocarcinoma … Stage IA Pancre… Stage IB Pancre… Stage IIA Pancr… Stage IIB Pancr…
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NCT00612612
NCT00574938
Details
2013-09-30
Interventional
128 
Fludarabine Fludarabine pho… Obatoclax Rituximab
Leukemia Leukemia, Lymph… Leukemia, Lymph… Leukemia, Proly… B-cell Chronic … Prolymphocytic … Refractory Chro… Stage I Chronic… Stage II Chroni… Stage III Chron… Stage IV Chroni…
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NCT00049582
Details
2013-09-30
Interventional
136 
Azacitidine Decitabine
Leukemia Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo… Myelodysplastic… Myelodysplastic… Myeloproliferat… Neoplasm Metast… Preleukemia Syndrome Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Atypical Chroni… Myelodysplastic… Previously Trea… Recurrent Adult… Secondary Acute… Secondary Myelo… Untreated Adult… de Novo Myelody…
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NCT00765323
Details
2013-09-27
Interventional
3169 
Octreotide Somatostatin
Acromegaly
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NCT00720850
Details
2013-09-27
Interventional
210 
Lenalidomide
Leukemia Leukemia, Myelo… Leukemia, Myelo… Myelodysplastic… Preleukemia Syndrome Acute Myelogeno…
Low recruitment, scientific rationale not applicable anymore to all patients and possible induction of GvHD by the study drug
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NCT01579279
2011-003939-56
Details
2013-09-26
Interventional
21 
Duloxetine Hydr…
Neuralgia Diabetic Neurop…
Study Stopped
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NCT00669695
2007-005286-35
Details
2013-09-24
Interventional
254 
Atorvastatin
Apnea Inflammation Sleep Apnea Syn… Sleep Apnea, Ob… Syndrome Obstructive Sle…
Interim analysis performed without efficient results
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NCT01295060
Details
2013-09-20
Interventional
312 
Octreotide
Acromegaly
Program was terminated for business reasons
-
NCT00884715
Details
2013-09-20
Interventional
1/210 
Octreotide
Carcinoid Tumor Malignant Carci… Serotonin Syndr… Syndrome Carcinoid Syndr…
Program was terminated for business reasons
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NCT01159301
Details
2013-09-19
Interventional
144 
Entinostat Histone Deacety… Sorafenib
Blast Crisis Hypereosinophil… Leukemia Leukemia, Basop… Leukemia, Eosin… Leukemia, Eryth… Leukemia, Megak… Leukemia, Monoc… Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo… Adult Acute Bas… Adult Acute Eos… Adult Acute Meg… Adult Acute Min… Adult Acute Mon… Adult Acute Mon… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Erythrole… Adult Pure Eryt… Blastic Phase C… Recurrent Adult… Unspecified Adu…
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NCT00679627
Details
2013-09-19
Interventional
32051 
Galantamine
Alzheimer Disea… Alzheimer's Dis…
Due to a pre-specified imbalance of deaths between treatment groups, the DSMB recommended early termination of the trial
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NCT01287338
Details
2013-09-17
Interventional
2143 
Olopatadine Hyd…
Conjunctivitis Conjunctivitis,… Seasonal Allerg…
Lack of definitive clinical results.
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NCT00065728
Details
2013-09-16
Interventional
3111 
Anecortave
Macular Degener…
Management decision
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NCT01511211
Details
2013-09-12
Interventional
40 
Dexamethasone Ropivacaine
Pain Total Knee Arth…
Other researchers have published results on a similar trial
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