Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01394848
Details
2013-12-04
Interventional
41 
Atorvastatin Clopidogrel Everolimus
Angina, Stable Stable Angina
Previous other study including EPC capture stent raised the issue of safety (significant high incidence of instent restenosis)
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NCT00329537
Details
2013-12-04
Interventional
211 
Sargramostim
Crohn Disease Crohn's Disease
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NCT00295165
NCT00295321
Details
2013-12-04
Interventional
333 
Sargramostim
Crohn Disease
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NCT00206713
Details
2013-12-04
Interventional
3264 
Sargramostim
Crohn Disease
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NCT00206700
NCT00185471
Details
2013-12-04
Interventional
2378 
Sargramostim
Crohn Disease
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NCT00206661
Details
2013-12-04
Interventional
1/222 
Molgramostim Sargramostim
Crohn Disease
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NCT01997203
Details
2013-11-28
Interventional
3100 
Interferons Ribavirin Vitamin D
Hepatitis Hepatitis A Hepatitis C Hepatitis C, Ch… Chronic Hepatit…
complete patients samples required
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NCT00350948
Details
2013-11-27
Interventional
3244 
Doxorubicin Liposomal doxor…
Ovarian Neoplas…
Business reasons
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NCT00216008
Details
2013-11-25
Interventional
2-
Docetaxel
Adenocarcinoma Adenocarcinomas… Esophageal Aden…
IRB Closure
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NCT01269658
Details
2013-11-21
Interventional
240 
Azithromycin Ophthalmic Solu…
Blepharitis
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NCT00199381
Details
2013-11-21
Interventional
3504 
Istradefylline
Parkinson Disea… Parkinson's Dis…
Additional long-term safety data no longer needed
The Sponsor decided to terminate the study early (not for safety reasons); as a result 323 subjects discontinued early. Mean duration of therapy was 18.7 months (0.4 to 31.4 months); median duration was 21.0 months. Total exposure 767 subject years.
NCT01498406
Details
2013-11-20
Interventional
23 
Cholecalciferol Ergocalciferols Vitamin D Vitamins
Lupus Erythemat… Cutaneous Lupus…
secondary to funding issues and low enrollment
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NCT00004159
Details
2013-11-20
Interventional
1/254 
Gemcitabine Paclitaxel
Carcinoma, Non-… Lung Neoplasms Lung Cancer
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NCT01432106
Details
2013-11-18
Interventional
10 
Ramipril Valsartan
Hypertension Metabolic Syndr… Syndrome
Novartis terminated all projects involving aliskiren. Findings of the DMC overseeing the ALTITUDE clinical trial found a higher incidence of adverse events.
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NCT01214291
Details
2013-11-15
Interventional
30 
Toremifene
Fractures, Bone Prostatic Neopl… Risk of Bone Fr…
cost of conducting the study and increased burden on the clinical trial professionals make it impossible for us to proceed with the development of the drug.
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NCT01726465
Details
2013-11-13
Interventional
250 
Acetylcysteine Methylprednisol… Methylprednisol… Methylprednisol… N-monoacetylcys… Prednisolone Prednisolone ac… Prednisolone he… Prednisolone ph…
Hepatic Insuffi… Liver Failure Reperfusion Inj… Insufficiency; … Ischemic Reperf… Liver Tumour
The first phase was completed
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NCT00301886
Details
2013-11-13
Interventional
30 
Ibandronic Acid Zoledronic Acid
Breast Neoplasm… Hypercalcemia Neoplasms Breast Cancer Hypercalcemia o… Metastatic Canc… Pain
withdrawn support for study
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NCT01628055
Details
2013-11-11
Interventional
10 
Antibodies Immunoglobulin … Immunoglobulins Immunoglobulins… Rho(D) Immune G… gamma-Globulins
Cerebral Infarc… Ischemia Ischemic Stroke Stroke
difficult recruitment and new black box warning for IVIG
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NCT00308113
Details
2013-11-08
Interventional
33 
Coenzyme Q10 Prednisone Ubiquinone
Muscular Dystro… Muscular Dystro… Duchenne Muscul…
New enrollment has been suspended, currently following previously enrolled participants
In December 2007 the CINRG Data Safety and Monitoring Board (DSMB) met and recommended to close the study as the AAN had released practice parameters recommending that all patients with DMD should be offered treatment with corticosteroids.
NCT00095641
Details
2013-11-08
Interventional
20 
Capecitabine
Carcinoma Carcinoma, Squa… Recurrence Squamous Cell C… Recurrent Squam… Recurrent Squam… Recurrent Squam… Recurrent Squam… Recurrent Squam…
no longer studying this disease site
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