Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01567540
2011-000823-34
Details
2014-01-20
Interventional
13 
Sitagliptin Pho…
Hepatitis Hepatitis A Hepatitis C Hepatitis C, Ch… Hepatitis, Chro…
New treatments available, which prevents additional recruitment.
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NCT00095693
Details
2014-01-16
Interventional
225 
Fluorodeoxygluc… Sorafenib
Adenocarcinoma,… Thyroid Cancer,… Thyroid Carcino… Thyroid Disease… Thyroid Neoplas… Anaplastic Thyr… Insular Thyroid… Recurrent Thyro… Stage III Folli… Stage III Papil… Stage IV Follic… Stage IV Papill…
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NCT01708057
2012-002900-42
Details
2014-01-15
Interventional
23 
Tiotropium Brom…
Lung Diseases Lung Diseases, … Pulmonary Disea… COPD Chronic Obstruc…
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NCT01818648
Details
2014-01-14
Interventional
40 
Exenatide
Short Bowel Syn… Syndrome
Study was withdrawn by PI due to decision to study a different medication.
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NCT00922129
Details
2014-01-14
Interventional
2/30 
Cyclosporine Cyclosporins MTOR Inhibitors Sirolimus Tacrolimus Temsirolimus
Prostatic Neopl… Prostate Cancer
Study did not start up as planned.
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NCT00819754
Details
2014-01-14
Interventional
1/223 
Bevacizumab Capecitabine Irinotecan Oxaliplatin
Colorectal Neop… Metastatic Colo…
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NCT00417768
Details
2014-01-14
Interventional
2/335 
Plasminogen Tissue Plasmino…
Abscess
Change in patient population no longer fit study criteria.
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NCT00337376
Details
2014-01-14
Interventional
123 
Albumin-Bound P… Paclitaxel Sirolimus
Advanced Solid …
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NCT00077948
Details
2014-01-10
Interventional
3-
Enoximone Metoprolol
Heart Failure Heart Failure, …
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NCT00051285
Details
2014-01-10
Interventional
3-
Enoximone
Heart Failure Heart Failure, …
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NCT01363310
Details
2014-01-08
Interventional
3-
Escitalopram Quetiapine Fuma…
Depression Depressive Diso… Depression With…
Termination of sponsorship
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NCT01065051
Details
2014-01-06
Interventional
21 
Riociguat
Hypertension Hypertension, P… Ventricular Dys… Ventricular Dys…
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The study was terminated prematurely due to low recruitment (one subject enrolled only). No statistical analyses of efficacy parameters were performed. Therefore, no clinically meaningful conclusions can be drawn from the data generated.
NCT00613730
Details
2014-01-06
Interventional
23 
Gemcitabine Panitumumab
Adenocarcinoma Pancreatic Neop… Cancer of Pancr… Cancer of the P… Pancreas Cancer Pancreatic Canc…
APPRISE closure prompted by SWOG S0205 not meeting primary endpoint-improving OS. APPRISE enrollment closure due to similar design;no unexpected safety data
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NCT00389675
Details
2014-01-06
Interventional
3661 
Darusentan Guanfacine
Hypertension
Study DAR-312 did not meet its primary co-endpoints.
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NCT00203047
Details
2014-01-06
Interventional
4
[1 Refs]
414 
(T,G)-A-L Glatiramer Acet… Prednisone
Multiple Sclero… Multiple Sclero… Sclerosis Relapsing Remit…
Slow enrollment decreased sample size; No unexpected safety issues.
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NCT01871480
Details
2013-12-30
Interventional
2-
Gefitinib
Adenocarcinoma Carcinoma, Non-… Lung Neoplasms Non-Small Cell …
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NCT01134627
NCT00381459
2005-004289-18
Details
2013-12-27
Interventional
2305 
Minocycline
Multiple Sclero… Multiple Sclero… Sclerosis
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NCT01071200
NCT00267761
2004-002218-13
Details
2013-12-27
Interventional
3133 
Follicle Stimul… Hormones
Infertility Reproductive Te…
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NCT00646763
Details
2013-12-20
Interventional
235 
Lenograstim Mitogens Sargramostim
Cytokines
Accrual goal met
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NCT00923234
Details
2013-12-18
Interventional
1-
Azacitidine Lenalidomide
Leukemia Leukemia, Myelo… Leukemia, Myelo… Myelodysplastic… Preleukemia Syndrome Acute Myelogeno…
The primary objective has already been answered with the number of recruited patients.
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