Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01131364
2007-006176-11
Details
2014-02-25
Interventional
1/229 
Doxorubicin
Breast Neoplasm… Advanced Solid … Breast Cancer
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NCT01055522
2007-005737-11
Details
2014-02-25
Interventional
2102 
Dacarbazine Interleukin-2
Melanoma Metastatic Mela…
-
-
NCT00489138
Details
2014-02-25
Interventional
49 
Ertapenem
To Assess the T…
-
-
NCT00701298
Details
2014-02-24
Interventional
130 
Azacitidine Decitabine Interferon alph… Interferon-alph… Interferons Peginterferon a…
Unspecified Adu…
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-
NCT00436579
Details
2014-02-24
Interventional
1110 
Sorafenib
Unspecified Adu…
-
-
NCT00112684
NCT01645540
Details
2014-02-24
Interventional
125 
Alvocidib
Neoplasms Unspecified Adu…
-
-
NCT00101205
Details
2014-02-24
Interventional
140 
Etoposide Etoposide phosp… Oxaliplatin
Burkitt Lymphom… Immunoblastic L… Intraocular Lym… Leukemia Leukemia, Hairy… Leukemia, Large… Leukemia, Lymph… Leukemia, Lymph… Lymphoma Lymphoma, Extra… Lymphoma, Large… Lymphoma, Large… Lymphoma, Large… Lymphoma, Non-H… Lymphoma, T-Cel… Lymphoma, T-Cel… Lymphoma, T-Cel… Lymphomatoid Gr… Mycoses Mycosis Fungoid… Plasmablastic L… Precursor Cell … Recurrence Sezary Syndrome Angioimmunoblas… B-cell Childhoo… B-cell Chronic … Childhood Burki… Childhood Diffu… Childhood Grade… Childhood Immun… Childhood Nasal… Hepatosplenic T… Noncutaneous Ex… Peripheral T-ce… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Cutan… Recurrent Mycos… Recurrent/Refra… Refractory Chro… Refractory Hair… Small Intestine… T-cell Childhoo… T-cell Large Gr… Unspecified Chi…
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NCT00096005
NCT01646905
NCT01664325
Details
2014-02-24
Interventional
136 
Bortezomib
Burkitt Lymphom… Hodgkin Disease Immunoblastic L… Leukemia Leukemia, Lymph… Leukemia, T-Cel… Leukemia-Lympho… Lymphoma Lymphoma, B-Cel… Lymphoma, B-Cel… Lymphoma, Extra… Lymphoma, Folli… Lymphoma, Large… Lymphoma, Large… Lymphoma, Large… Lymphoma, Mantl… Lymphoma, Non-H… Lymphoma, T-Cel… Lymphoma, T-Cel… Lymphomatoid Gr… Mycoses Mycosis Fungoid… Plasmablastic L… Precursor Cell … Recurrence Sezary Syndrome Syndrome Waldenstrom Mac… AIDS-related Pe… Adult Grade III… Anaplastic Larg… Angioimmunoblas… Extranodal Marg… Nodal Marginal … Recurrent Adult… Recurrent Adult… Recurrent Adult… Recurrent Adult… Recurrent Adult… Recurrent Adult… Recurrent Adult… Recurrent Adult… Recurrent Adult… Recurrent Cutan… Recurrent Grade… Recurrent Grade… Recurrent Grade… Recurrent Mantl… Recurrent Margi… Recurrent Mycos… Recurrent Small… Stage III Adult… Stage III Adult… Stage III Adult… Stage III Adult… Stage III Adult… Stage III Adult… Stage III Adult… Stage III Adult… Stage III Cutan… Stage III Grade… Stage III Grade… Stage III Grade… Stage III Mantl… Stage III Margi… Stage III Mycos… Stage III Small… Stage IV Adult … Stage IV Adult … Stage IV Adult … Stage IV Adult … Stage IV Adult … Stage IV Adult … Stage IV Adult … Stage IV Adult … Stage IV Cutane… Stage IV Grade … Stage IV Grade … Stage IV Grade … Stage IV Mantle… Stage IV Margin… Stage IV Mycosi… Stage IV Small … Unspecified Adu… Waldenström Ma…
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NCT01348607
Details
2014-02-21
Interventional
21 
Methylphenidate Modafinil
Central Nervous… Disorders of Ex… Fatigue Nervous System … Sleepiness Central Nervous… Specific Disord…
Study only randomized 1 subject and was determined not feasible by DSMB
This study was closed prior to completion due to a lack of feasibility and low accrual by the Data Monitoring and Safety Board (DSMB).
NCT01017263
Details
2014-02-20
Interventional
414 
Dextroamphetami… Lisdexamfetamin…
Attention Defic… Glucose Intoler… Hyperkinesis Obesity Attention Defic…
Due very high screen fail rate, pre study feasibility not consistent with screened population.
Study was terminated due to the high number of failures of lab criteria for glucose intolerance which is one of the entry criterion. No data were analyzed.
NCT01591980
Details
2014-02-19
Interventional
40 
Pregabalin
Headache Pain, Postopera… Chronic Postope…
Pfizer Canada and the SMH ORA could not come into an agreement on responsibility to be the Importer of Record for the trial.
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NCT01153958
Details
2014-02-13
Interventional
4133 
Chlorquinaldol Metronidazole
Vaginal Disease… Vaginosis, Bact…
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-
NCT01075815
2008-002281-55
Details
2014-02-13
Interventional
276 
Follicle Stimul… Hormones
Infertility Ovulation Induc…
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NCT00553514
Details
2014-02-13
Interventional
271 
Chorionic Gonad… Follicle Stimul…
Ovulation Induc…
The study was terminated after Merck Serono had taken the decision not to pursue the development of AS900672-enriched in ovulation induction
The study was terminated after Merck Serono had taken the decision not to pursue the development of AS900672-enriched in ovulation induction
NCT01612910
Details
2014-02-12
Interventional
20 
3,3'-diindolylm…
Breast Neoplasm… Breast Cancer F…
Research cancelled.
-
NCT01288664
Details
2014-02-12
Interventional
30 
Tacrolimus
Lupus Nephritis Nephritis
sponsor withdraw from this study
-
NCT01622556
Details
2014-02-11
Interventional
26 
Busulfan Fludarabine Thymoglobulin
Hematologic Neo… Neoplasms Hematologic Mal…
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-
NCT00160485
Details
2014-02-11
Interventional
40 
Glyburide
Diabetes Mellit… Diabetes, Gesta… Gestational Dia…
Active Duty principle investigator currently deployed
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NCT01059123
2008-006794-32
Details
2014-02-07
Interventional
410 
Amoxicillin
Erysipelas
Insufficient number of inclusion
-
NCT00848107
Details
2014-02-07
Interventional
2115 
Treprostinil
Scleroderma, Di… Scleroderma, Sy… Sclerosis Systemic Sclero…
The TDE-DU-202 extension study was discontinued after the randomized, placebo-controlled TDE-DU-201 study did not meet its primary efficacy objective.
Interpretation of the change in digital ulcer status was limited by the lack of a control group and the discontinuation of the study prior to subjects completing all scheduled visits.