Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00303862
Details
2014-05-21
Interventional
210 
Cediranib
Carcinoma Carcinoma, Rena… Clear Cell Rena… Recurrent Renal… Stage IV Renal …
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NCT00184067
Details
2014-05-21
Interventional
223 
Monatide (IMS 3…
Melanoma
Primary PI left institution
-
NCT01684657
Details
2014-05-20
Interventional
3-
Asenapine
Stuttering
Study transferring to another facility
-
NCT00383565
Details
2014-05-20
Interventional
29 
Romidepsin
Lymphoma Lymphoma, Large… Lymphoma, Mantl… Lymphoma, Non-H… Recurrence Recurrent Adult… Recurrent Mantl…
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NCT02034097
Details
2014-05-19
Interventional
20 
Erlotinib Hydro…
Carcinoma, Non-… Lung Neoplasms Cancer
GSK has decided to terminate the Product Development of foretinib and conclude our Development Agreement with Exelixis
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NCT01309412
Details
2014-05-19
Interventional
19 
Siltuximab
Multiple Myelom… Neoplasms, Plas…
Protocol was stopped due to the safety issue in Global
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NCT00157248
Details
2014-05-19
Interventional
2361 
Dabigatran
Atrial Fibrilla… Stroke
-
-
NCT01011816
Details
2014-05-16
Interventional
3220 
Fibrin Tissue A…
Back Pain Intervertebral … Low Back Pain Chronic Low Bac… Degenerative Di… Internal Disc D…
Stopped prior to last subject's last extended follow-up visit (78 weeks) due to lack of efficacy at the primary study endpoint (26 weeks)
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NCT00493428
Details
2014-05-16
Interventional
20 
Baclofen
Carcinoma Carcinoma, Hepa… Hepatocellular …
The study have been stoped because the protocol is going to be modify.
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NCT01166126
Details
2014-05-15
Interventional
24 
MTOR Inhibitors Sirolimus Temsirolimus
Melanoma Mucosal Melanom… Recurrent Melan… Stage IV Melano…
-
The study was terminated due to overall low accrual and a high rate of screening failures. Accrual goal was 38 participants and only 4 participants were actually treated.
NCT01129557
Details
2014-05-15
Interventional
4
[1 Refs]
46 
Aliskiren Valsartan
Diabetic Nephro… Glomerulonephri… Glomerulonephri… Glomerulonephri… Glomerulosclero… Kidney Diseases Nephrosclerosis Diabetic Nephro… Focal Segmental… Glomerulopathy … Hypertensive Ne… IgA Nephropathy Proteinuric Kid…
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NCT00879229
Details
2014-05-15
Interventional
340 
Ambrisentan
Fibrosis Hypertension Hypertension, P… Idiopathic Pulm… Pulmonary Fibro… Pulmonary Hyper…
-
Study GS-US-300-0128 was terminated early with enrollment of 40 of 225 planned subjects.
NCT00684996
Details
2014-05-15
Interventional
1/25 
Antibodies Antibodies, Mon… Antineoplastic … Bevacizumab Immunoglobulins
Carcinoma Carcinoma, Rena… Recurrent Renal… Renal Cell Carc… Stage III Renal… Stage IV Renal …
-
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NCT00517192
Details
2014-05-14
Interventional
340 
Darunavir Ritonavir Tipranavir
HIV Infections
-
-
NCT00447902
2005-005023-33
Details
2014-05-14
Interventional
311 
Ritonavir Tipranavir
HIV Infections
-
Due to an early termination of the trial no analysis has been performed for primary and secondary endpoints
NCT00023946
Details
2014-05-14
Interventional
250 
Epothilone B Epothilones
Bile Duct Neopl… Carcinoma Carcinoma, Hepa… Cholangiocarcin… Gallbladder Neo… Liver Neoplasms Recurrence Adult Primary C… Adult Primary H… Advanced Adult … Cholangiocarcin… Cholangiocarcin… Localized Extra… Localized Gallb… Localized Resec… Localized Unres… Recurrent Adult… Recurrent Extra… Recurrent Gallb… Unresectable Ex… Unresectable Ga…
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NCT01471197
2011-000732-29
Details
2014-05-12
Interventional
29 
Ipilimumab Pemetrexed
Lung Neoplasms Lung Cancer - N…
Administrative reasons
At the time of the early termination of this study, most participants only had only one on-study tumor assessment performed. Therefore, the tumor response-related endpoints were too immature to report.
NCT00293111
Details
2014-05-12
Interventional
2-
Etodolac
Multiple Myelom… Neoplasms, Plas…
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-
NCT00121420
Details
2014-05-09
Interventional
2-
Motexafin gadol…
Brain Neoplasms Neoplasm Metast… Neoplasms Neoplasms, Seco…
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NCT01981499
Details
2014-05-08
Interventional
131 
Cetirizine
Migraine Disord… Migraine
The trial was prematurely terminated on 01April2014 due to safety concerns.
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