Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00662220
2007-005344-25
Details
2014-07-14
Interventional
3110 
Interferon-alph… Peginterferon a… Ribavirin
Hepatitis Hepatitis A Hepatitis C Hepatitis C, Ch… Hepatitis, Chro… Chronic Hepatit…
Due to the arrival of DAAs replacing standard of care for genotype 1 patients the VIRID study had to be terminated.
-
NCT01505881
2011-002285-21
Details
2014-07-11
Interventional
2158 
Dabigatran Warfarin
Thromboembolism Heart Valve Pro…
-
This study was terminated prematurely due to safety concerns arising during conduct of the trial.
NCT01043601
Details
2014-07-11
Interventional
20 
Formoterol Fuma…
COPD
Similar data obtained in another study [see NCT01085045], therefore study not implemented.
-
NCT02184260
Details
2014-07-10
Interventional
458 
Dipyrone
Ischemic Stroke Stroke
-
-
NCT02183246
Details
2014-07-08
Interventional
33 
Porfiromycin
Head and Neck N…
-
-
NCT02182700
Details
2014-07-08
Interventional
347 
Albuterol Bromides Ipratropium
Asthma
-
-
NCT01603394
Details
2014-07-08
Interventional
49 
Pregabalin
Neuralgia Neuralgia, Post… Postherpetic Ne…
See termination reason in detailed description.
Outcome measure PCS was removed in protocol amendment1. Study stopped due to low enrolment and not safety. Efficacy analyses were not performed; safety results are described. Overall risk-benefit of pregabalin has not changed due to trial termination
NCT01187615
Details
2014-07-08
Interventional
19 
Cisplatin Pemetrexed
Carcinoma, Non-… Lung Neoplasms Small Cell Lung…
-
-
NCT00890097
Details
2014-07-03
Interventional
3772 
Ophthalmic Solu…
Atrophy Geographic Atro… Macular Degener… Age-Related Mac…
Treatment ineffective
-
NCT01145404
Details
2014-07-02
Interventional
2-
Capecitabine Lapatinib
Esophageal Neop… GastroEsophagea…
Changes of SoC for third line therapy resulting in poor recruitment
-
NCT00002948
Details
2014-07-02
Interventional
1-
Topotecan
Unspecified Adu…
-
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NCT00608231
Details
2014-07-01
Interventional
2/30 
Dexmedetomidine
Dystonia Essential Tremo… Parkinson Disea… Parkinson's Dis…
Intraoperative recording could not be maintained for required period
-
NCT00440271
2005-005264-86
Details
2014-06-27
Interventional
333 
Enfuvirtide Maraviroc Raltegravir Pot… Reverse Transcr… Ritonavir Tipranavir
HIV Infections
-
The study was terminated early due to low patient enrollment, and, therefore, no analysis was performed on the primary and secondary endpoints
NCT00165828
2005-000260-57
Details
2014-06-27
Interventional
4157 
Zonisamide
Epilepsy Seizures
-
-
NCT01890408
Details
2014-06-26
Interventional
25 
Ropivacaine
Hepatic Resecti… Laparotomy
promoter decision
-
NCT00975299
2008-007460-42
Details
2014-06-26
Interventional
116 
Bombesin
Prostatic Neopl… Diagnostic Imag…
-
-
NCT00076401
Details
2014-06-26
Interventional
2-
Motexafin gadol…
Leukemia Leukemia, Lymph… Leukemia, Lymph… Leukemia, Lymph…
-
-
NCT02092961
Details
2014-06-25
Interventional
2198 
Adalimumab
Arthritis Arthritis, Rheu… Rheumatoid Arth…
AZ decision to discontinue fostamatinib development in RA; rights to fostamatinib returned to Rigel Pharmaceuticals.
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NCT02172508
Details
2014-06-24
Interventional
415 
Tiotropium Brom…
Dyspnea Lung Diseases Lung Diseases, … Pulmonary Disea…
-
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NCT02172131
Details
2014-06-24
Interventional
164 
Olodaterol
Healthy
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