Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01704027
Details
2014-09-18
Interventional
228 
Androgens
Prostatic Neopl… Prostate Cancer
termination of the trial after interim analysis. the main criterion could not be reached
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NCT01363349
NCT01365299
Details
2014-09-18
Interventional
2/3269 
Risperidone
Schizophrenia Cognitive Effec…
pre-planned interim analysis of the Phase II/III CLARITY trial of BL-1020 indicate that the trial would not meet the pre-specified primary efficacy endpoint.
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NCT01339026
2010-020219-35
Details
2014-09-18
Interventional
444 
Clopidogrel Prasugrel Hydro…
Acute Coronary … Cardiovascular … Syndrome Cardiovascular …
Change in guidelines favouring newer antiplatelet drugs in ACS
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NCT01031810
Details
2014-09-18
Interventional
413 
Tranylcypromine
Depression Depressive Diso… Depressive Diso… Depressive Diso… Major Depressiv…
Needed PET facility closed
Early termination leading to small numbers of subjects analyzed
NCT02242812
Details
2014-09-17
Interventional
424 
Metoprolol Telmisartan
Hypertension
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NCT00240162
Details
2014-09-17
Interventional
221 
Vatalanib
Multiple Myelom… Neoplasms, Plas…
investigator letter from drug manufacturer stating animal studies showed increased risk of cancer which was an unknown adverse event
In November 2008, it was reported that the drug might have carcinogenic potential in animal models. At that time, the remaining three patients were taken off study.
NCT01870284
Details
2014-09-16
Interventional
30 
Adalimumab Ixekizumab
Spondylarthriti… Spondylitis Spondylitis, An…
Due to unexpected operational issues outside of Lilly's control the study has been closed
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NCT01164917
Details
2014-09-16
Interventional
116 
Antibodies, Mon…
Lupus Erythemat… Lupus Erythemat… Cutaneous Lupus Discoid Lupus Lupus Systemic Lupus …
The 16 subjects enrolled in the study should enable Amgen to adequately assess safety and tolerabili
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NCT00784966
Details
2014-09-16
Interventional
1/20 
Etanercept
Diabetes Mellit… Diabetes Mellit… Type 1 Diabetes…
University decision.
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NCT02239835
Details
2014-09-15
Interventional
279 
Ritonavir Saquinavir Tipranavir
HIV Infections
-
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NCT01337427
Details
2014-09-15
Interventional
30 
Interferon beta… Interferon-beta Interferons
Multiple Sclero… Multiple Sclero… Sclerosis Relapsing Remit…
The study was not feasible to conduct in the US and abroad.
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NCT01875107
Details
2014-09-12
Interventional
40 
Insulin
Hyperglycemia Hyperglycemia i…
Time constraints of primary investigator.
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NCT01579578
Details
2014-09-12
Interventional
239 
Paclitaxel
Metastatic, Gas…
AstraZeneca sponsored trials of AZD8931 have been halted
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NCT02154048
Details
2014-09-11
Interventional
25 
Dexamethasone Ropivacaine
Surgery, Hand
-
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NCT02235428
Details
2014-09-10
Interventional
43 
Albuterol Bromides Ipratropium
Asthma
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NCT00498433
Details
2014-09-10
Interventional
246 
Aliskiren Amlodipine
Hypertension Obesity Obesity, Abdomi… Abdominal Obesi…
Early termination resulted from interim analysis of the ALTITUDE trial
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NCT00208936
Details
2014-09-09
Interventional
2-
Fluorouracil
Esophageal Dise… Esophageal Neop…
-
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NCT01841008
Details
2014-09-05
Interventional
2/335 
Tacrolimus
Pigmentation Di… Vitiligo
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NCT01786226
Details
2014-09-05
Interventional
2/3
[1 Refs]
220 
Mifepristone
Leiomyoma Myofibroma Uterine Fibroid…
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NCT00177411
Details
2014-09-05
Interventional
10 
Hormones Parathyroid Hor… Parathyroid Hor…
Osteoporosis
Protocol design was changed so it no longer fit the description of this study.
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