Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01659242
Details
2014-12-02
Interventional
41 
Leflunomide Methotrexate Sulfasalazine
Arthritis Arthritis, Rheu… Rheumatoid Arth…
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NCT00729404
2008-001198-13
Details
2014-12-02
Interventional
217 
Ethinyl Estradi… Femovan Gestodene
Contraception Ovulation Inhib…
-
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NCT01329549
Details
2014-11-27
Interventional
12 
Carboplatin Nintedanib
Ovarian Neoplas…
-
The trial was prematurely terminated because of worldwide disruption of pegylated liposomal doxorubicin (PLD) supplies.
NCT00940784
Details
2014-11-26
Interventional
20 
Aspirin Clopidogrel
Polycythemia Polycythemia Ve…
Could not get drug
-
NCT00798304
2008-001457-18
Details
2014-11-26
Interventional
246 
Vaccines
Meningitis Meningitis, Men…
Following program review within Pfizer, decision was made not to go ahead with this study. This study is cancelled
Immunogenicity results were not reported because the study was terminated due to the reactogenicity profile of the vaccine in infants prior to the first scheduled post-vaccination blood draw and no immunogenicity data were collected.
NCT02048475
2009-014620-36
Details
2014-11-25
Interventional
40 
Desflurane
Anesthesia
administrative reasons.
-
NCT00333229
2004-002831-14
Details
2014-11-25
Interventional
411 
Zoledronic Acid
Breast Neoplasm… Primary Hormone…
Due to rare patient population, planned number of patients could not be recruited in a reasonable timeframe. Recruitment was stopped prematurely.
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NCT01238029
Details
2014-11-21
Interventional
112 
Capecitabine Lapatinib Vinorelbine
Breast Neoplasm… Failure or Cont… First or Second… HER2 Positive Metastatic Brea…
new methods of treatment, no more patients appilicable for study
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NCT01464671
Details
2014-11-20
Interventional
4260 
Bivalirudin Heparin
Coronary Artery… Coronary Diseas… Myocardial Isch…
DSMB halted the study early due to futility. There were no safety concerns.
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NCT01465815
Details
2014-11-19
Interventional
1/20 
Erlotinib Hydro…
Carcinoma Carcinoma, Squa… Recurrence Recurrent Skin … Recurrent Squam… Squamous Cell C… Stage III Squam… Stage IVA Squam… Stage IVB Squam…
Drug manufacturer, Astellas Pharma, informed us that safety and efficacy of Erlotinib and OSI-906 in other oncology studies was determined to be unfavorable.
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NCT02234869
Details
2014-11-17
Interventional
40 
Interferon beta… Interferon beta… Interferon-beta Interferons
Multiple Sclero… Sclerosis Relapsing Multi…
Due to a change in Biogen Idec's medical research plans.
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NCT01650805
Details
2014-11-17
Interventional
3307 
Imatinib Mesyla… Ponatinib
Leukemia Leukemia, Myelo… Leukemia, Myelo… Chronic Myeloid…
Study terminated based on evaluation of safety data.
Trial was discontinued early.
NCT00708357
Details
2014-11-17
Interventional
112 
omega-N-Methyla…
Ocular Physiolo… Regional Blood …
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NCT00024687
Details
2014-11-14
Interventional
10 
Immunotoxins
Neoplasms
Support withdrawn - Study continued by NCI - see record NCT00006981
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NCT01006096
Details
2014-11-10
Interventional
20 
Erlotinib Hydro…
Psoriasis
IND not obtained
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NCT01966575
Details
2014-11-06
Interventional
40 
Medroxyprogeste… Medroxyprogeste… Progestins
Infertility Polycystic Ovar…
Recent findings suggest that letrozole may be a superior Clomiphene Citrate.
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NCT01737359
Details
2014-11-05
Interventional
22 
Tenofovir
Acquired Immuno… HIV Infections Human Immunodef…
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NCT01417481
Details
2014-11-05
Interventional
213 
Glycine
Cystic Fibrosis Fibrosis
Some of the researchers finished their participation in the study.
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NCT01092858
2009-017139-16
Details
2014-11-05
Interventional
44 
Methyltestoster… Testosterone Testosterone 17… Testosterone en… Testosterone un…
Hypogonadism
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NCT01088763
Details
2014-11-05
Interventional
1129 
2,2-dimethyl-N-… Dexamethasone
Adamantinoma Adenoma Adenoma, Acidop… Adenoma, Basoph… Adenoma, Chromo… Astrocytoma Choriocarcinoma Choroid Plexus … Craniopharyngio… Endodermal Sinu… Ependymoma Germinoma Glioma Leukemia Leukemia, Large… Leukemia, Lymph… Leukemia, T-Cel… Lymphoma Lymphoma, Large… Lymphoma, Non-H… Lymphomatoid Gr… Medulloblastoma Meningioma Neoplasms Neuroectodermal… Neuroectodermal… Oligodendroglio… Pinealoma Pituitary Disea… Pituitary Neopl… Precursor Cell … Prolactinoma Recurrence Rhabdoid Tumor Spinal Cord Neo… Teratoma Childhood Atypi… Childhood Centr… Childhood Centr… Childhood Centr… Childhood Centr… Childhood Centr… Childhood Choro… Childhood Crani… Childhood Epend… Childhood Grade… Childhood Grade… Childhood Grade… Childhood Infra… Childhood Medul… Childhood Mixed… Childhood Oligo… Childhood Supra… Gonadotroph Ade… Pituitary Basop… Pituitary Chrom… Pituitary Eosin… Prolactin Secre… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Child… Recurrent Pitui… Recurrent/Refra… T-cell Childhoo… T-cell Large Gr… TSH Secreting A… Unspecified Chi…
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