Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01696825
Details
2014-12-16
Interventional
13 
Diazepam
Metabolism, Dru…
-
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NCT00053911
Details
2014-12-16
Interventional
3-
Anastrozole Cyclophosphamid… Docetaxel Epirubicin Fluorouracil Goserelin Tamoxifen
Breast Neoplasm… Breast Cancer
-
-
NCT01721707
Details
2014-12-11
Interventional
30 
Brinzolamide Latanoprost
Glaucoma Glaucoma, Open-… Hypertension Ocular Hyperten… Open Angle Glau…
withdrawn by industry
-
NCT01721694
Details
2014-12-11
Interventional
30 
Azithromycin Loteprednol Eta…
Blepharitis Communicable Di… Conjunctivitis Conjunctivitis,… Infections Inflammation Keratitis Infection Assoc… Ocular Inflamma…
withdrawn by industry
-
NCT00678288
2007-005083-28
Details
2014-12-11
Interventional
216 
Interferons Sorafenib
Carcinoma Carcinoma, Rena…
-
The study was terminated early by the Sponsor due to low accrual. No efficacy analyses were performed.
NCT01519076
Details
2014-12-10
Interventional
17 
Coal Tar
Ischemic Stroke Stroke
Sponsor Request
-
NCT00660062
Details
2014-12-09
Interventional
447 
Citalopram Dexetimide Escitalopram Nortriptyline
Depression Depressive Diso… Recurrence Major Depressio…
Slow inclusion
-
NCT00511043
Details
2014-12-09
Interventional
220 
Vatalanib
Lymphoma Lymphoma, Large… Lymphoma, Large…
Manufacturer stopped drug development
-
NCT00510081
Details
2014-12-09
Interventional
30 
Calcium
Jowls
The study was not executed. No subjects were enrolled.
-
NCT00306137
2005-004689-18
Details
2014-12-09
Interventional
3104 
Aprotinin
Blood Loss, Sur… Esophageal Neop…
-
-
NCT01953445
Details
2014-12-08
Interventional
20 
Paclitaxel
Breast Neoplasm…
The study sponsor found the trial to be not viable.
-
NCT01291784
Details
2014-12-08
Interventional
1
[1 Refs]
3 
Antibodies Antibodies, Mon…
Polycythemia Polycythemia Ve… Primary Myelofi… Thrombocythemia… Thrombocytosis Myelofibrosis Polycythemia Ve… Post-essential …
Early termination when the drug was no longer made available by the pharmaceutical company due to unanticipated management and administrative decisions.
Early termination when the drug was no longer made available by the pharmaceutical company due to unanticipated management and administrative decisions. Limited patient data (2 evaluable patients), a dose accumulation ratio cannot be determined.
NCT01226992
Details
2014-12-08
Interventional
2/381 
Vancomycin
Clostridium Inf… Communicable Di… Infections Recurrence Laboratory Conf… Recurrent Clost…
Unavailable study resources
-
NCT00095316
Details
2014-12-05
Interventional
3-
Caspofungin
Candidiasis
-
-
NCT02028910
Details
2014-12-04
Interventional
320 
Ondansetron
Gastroenteritis Vomiting
-
-
NCT00516399
Details
2014-12-04
Interventional
378 
Natamycin Ophthalmic Solu… Povidone Povidone-Iodine
Corneal Ulcer Keratitis Fungal Keratiti…
The DSMC decided it appeared futile to attempt to demonstrate non-inferiority of povidone-iodine to Natamycin.
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NCT01666431
Details
2014-12-03
Interventional
210 
Lapatinib
Carcinoma Carcinoma, Squa… Squamous Cell C…
-
-
NCT01164046
2009-015336-15
Details
2014-12-03
Interventional
356 
Acenocoumarol Bemiparin Certoparin Dalteparin Enoxaparin Heparin Heparin, Low-Mo… Nadroparin Phenprocoumon Reviparin Tinzaparin Vitamin K Warfarin
Embolism Pulmonary Embol… Thromboembolism Thrombosis Venous Thromboe… Venous Thrombos… Neoplasms
Due to slow inclusion of patients
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NCT00570960
Details
2014-12-03
Interventional
48 
Dextrans
Peritonitis Spontaneous Bac…
drug product became unavilable
The study was terminated early because the manufacturer of Dextran 70 ceased all production of the study drug approximately 10 months into the study. It was felt by the principle investigator that continuation of the study was impossible.
NCT02062892
Details
2014-12-02
Interventional
40 
Everolimus Sirolimus
Kidney Transpla…
Patients meeting the inclusion/ exclusion criteria did not agree to participate. It became obvious that recruitment goals could not be met.
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