Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01027923
Details
2015-01-26
Interventional
16 
Cytarabine Etoposide Mitoxantrone Plerixafor
Leukemia Leukemia, Myelo… Leukemia, Myelo…
Withdrawal of support from sponsor
-
NCT00646282
Details
2015-01-26
Interventional
412 
1 alpha-hydroxy…
Hyperparathyroi… Hyperparathyroi…
slow enrollment and discontinued once original principal investigator left Emory
Due to slow enrollment and primary investigator leaving institution, the study was terminated. Subjects were notified and those on active drug returned to their physicians to be treated according to standard of care.
NCT00282165
Details
2015-01-26
Interventional
48 
Naratriptan
Aggression Antisocial Pers… Disruptive, Imp… Personality Dis… Psychotic Disor… Impulse Regulat… Intermittent Ex…
Required number of subjects to be included could not be accomplished
-
NCT01965301
2013-000697-30
Details
2015-01-21
Interventional
148 
Diphenhydramine Promethazine
Healthy Male Vo…
-
-
NCT01386398
2009-011021-13
Details
2015-01-21
Interventional
30 
Bortezomib Vorinostat
Lymphoma
Company withdrew interest
-
NCT00818675
Details
2015-01-21
Interventional
280 
Sirolimus
Carcinoma, Non-… Lung Neoplasms Non-Small Cell …
-
-
NCT00060671
NCT00062361
Details
2015-01-19
Interventional
3
[1 Refs]
-
Pixantrone Rituximab
Lymphoma Lymphoma, Folli… Lymphoma, Non-H… Lymphoma, Low-G… Lymphoma, Mixed… Lymphoma, Small…
-
-
NCT01777217
Details
2015-01-16
Interventional
48 
Solifenacin Suc…
Urinary Bladder… Over-Active Bla…
Terminated
Early termination leading to small numbers of subjects analyzed.
NCT00266357
Details
2015-01-14
Interventional
2-
Gaboxadol
Sleep Initiatio… Primary Insomni…
-
-
NCT00094666
Details
2015-01-14
Interventional
3-
Gaboxadol
Sleep Initiatio… Primary Insomni…
-
-
NCT00312650
Details
2015-01-12
Interventional
2-
Doxorubicin Gemcitabine Liposomal doxor…
Carcinoma, Ovar… Ovarian Neoplas… Ovarian Carcino…
-
-
NCT01772056
2008-005360-14
Details
2015-01-09
Interventional
354 
Fluticasone
Dermatitis Dermatitis, Ato…
Patient recruitment is very slow, economic grant has ended and the number of patients is enough according to sample size (22 children/ arm).
-
NCT00209560
Details
2015-01-09
Interventional
3168 
Fospropofol
Carpal Tunnel S… Arthroscopy Bunionectomy Carpal Tunnel Osteotomy
-
Analysis of results from a previous fospropofol study (3000-0410) completed during the enrollment of this study indicated that the dosing regimen needed to be re-evaluated. The study was prematurely terminated after 168 subjects were randomized.
NCT00975767
Details
2015-01-08
Interventional
1126 
Docetaxel Erlotinib Hydro…
Carcinoma, Non-… Lung Neoplasms Neoplasms Advanced Malign…
The study was terminated due to a need for a reformulation of the study drug. Phase 1 completed, no patients enrolled in Phase 2.
-
NCT00511576
Details
2015-01-08
Interventional
1-
Docetaxel Mocetinostat
Breast Neoplasm… Carcinoma, Non-… Lung Neoplasms Prostatic Neopl… Stomach Neoplas… Breast Cancer Gastric Cancer Lung Cancer Non-Small-Cell … Prostate Cancer Prostatic Cance… Pulmonary Cance… Stomach Cancer
Celgene terminated its collaboration agreement with MethylGene for the development of MGCD0103. All Celgene-sponsored trials with MGCD0103 will be closed.
-
NCT02333851
Details
2015-01-07
Interventional
472 
Insulin, pork; …
Diabetes Mellit… Diabetes Mellit… Type 2 Diabetes…
Safety reasons
-
NCT01224795
Details
2015-01-06
Interventional
31 
Peramivir
Influenza, Huma… Influenza
This study was terminated for administrative reasons
-
NCT01492920
Details
2014-12-31
Interventional
30 
Acetylcarnitine
Brenner Tumor Carcinoma Carcinoma, Endo… Cystadenocarcin… Cystadenocarcin… Cystadenocarcin… Fallopian Tube … Neurotoxicity S… Peripheral Nerv… Recurrence Fatigue Malignant Ovari… Neuropathy Neurotoxicity S… Ovarian Brenner… Ovarian Clear C… Ovarian Endomet… Ovarian Mucinou… Ovarian Serous … Pain Recurrent Fallo… Recurrent Ovari… Recurrent Prima…
Withdrawn
-
NCT01183455
Details
2014-12-31
Interventional
20 
Alpha 1-Antitry… Protease Inhibi…
Diabetes Mellit… Diabetes Mellit…
Sponsor decision-lack of mechanistic signal and competing industry studies
-
NCT00352859
Details
2014-12-30
Interventional
42 
Gemcitabine Interferons Sorafenib
Carcinoma Carcinoma, Rena…
-
-