Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01688791
2012-002799-14
Details
2015-02-10
Interventional
137 
Carboplatin Paclitaxel
Neoplasms Advanced Cancer
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NCT01010373
Details
2015-02-10
Interventional
2-
Ammonium trichl…
Leukemia Leukemia, Myelo… Leukemia, Myelo… Myelodysplastic… Preleukemia Syndrome Acute Myeloid L… Myelodysplastic…
The sponsor is currently focusing on different indications
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NCT02358642
Details
2015-02-09
Interventional
493 
Angiotensin-Con… Enzyme Inhibito… Lisinopril
Deglutition Dis… Pneumonia Neurological Dy…
The interim analysis suggested that low dose lisinopril given to be tube fed older patients with neuroligical dysphagia had increased mortality.
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NCT00453453
Details
2015-02-09
Interventional
417 
Natriuretic Pep…
Heart Failure Congestive Hear…
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-
NCT02048358
2013-004077-28
Details
2015-02-06
Interventional
147 
Methylprednisol… Methylprednisol… Methylprednisol… Prednisolone Prednisolone ac… Prednisolone he… Prednisolone ph…
Multiple Sclero… Sclerosis Healthy Volunte…
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NCT01352702
2011-000504-18
Details
2015-02-05
Interventional
446 
Dabigatran Phenprocoumon
Acute Coronary … Atherosclerosis Atrial Fibrilla… Coronary Artery… Coronary Diseas… Heart Diseases Myocardial Isch… Coronary Heart …
Slow recruitment; Study was terminated for futility reasons
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NCT00539968
Details
2015-02-05
Interventional
1/25 
Docetaxel Lonafarnib
Breast Cancer Gastric Cancer Lung Cancer Ovarian Cancer Prostate Cancer
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NCT00420589
Details
2015-02-05
Interventional
3
[1 Refs]
1000 
N-(3-(4-chlorop…
Obesity
The overall profile does not support development for obesity
-
NCT00131404
Details
2015-02-05
Interventional
3
[1 Refs]
2400 
N-(3-(4-chlorop…
Obesity
The overall profile does not support development for obesity
-
NCT01813656
Details
2015-02-04
Interventional
410 
Aripiprazole
Methamphetamine…
Aripiprazole arm had obvious adverse reactions,especially akathisia.
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NCT01813643
Details
2015-02-04
Interventional
450 
Aripiprazole Risperidone
Methamphetamine…
Effects of aripiprazole was not obvious and showed adverse reaction obviously
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NCT01275976
Details
2015-02-04
Interventional
311 
Complement C1 I… Complement C1 I… Complement C1s
Hip Fractures Inflammation Multiple Organ … Wounds and Inju… Multiple Organ … Sepsis Trauma
Futility and limited feasibility
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NCT00913003
Details
2015-02-04
Interventional
422 
Lidocaine
Pain
PI terminated employment with the University
This study was terminated early because the PI left the institution.
NCT00798213
Details
2015-02-04
Interventional
2
[1 Refs]
29 
Gemtuzumab
Leukemia Leukemia, Lymph… Leukemia, Myelo… Leukemia, Myelo… Precursor Cell … Lymphoblastic L…
-
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NCT01762670
Details
2015-02-03
Interventional
1/28 
Metronidazole
Vaginal Disease… Vaginosis, Bact… Bacterial Vagin…
Company decided to stop study for reasons other than safety
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NCT01417403
Details
2015-02-03
Interventional
110 
Hydroxychloroqu…
Bone Marrow Dis… Bone Neoplasms Neoplasm Metast… Bone Metastases Unspecified Adu…
Recently published data that has shown HCQ to be safe when combined with chemo and or radiation at even higher doses than what is used in this study.
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NCT02271347
Details
2015-02-02
Interventional
20 
Brincidofovir
Hemorrhagic Fev… Virus Diseases Ebola Virus
Suspended Development Program
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NCT00500006
Details
2015-01-30
Interventional
1
[1 Refs]
3 
Dasatinib
Leukemia Leukemia, Myelo… Leukemia, Myelo… Philadelphia Ch… Precursor Cell … Chronic Myeloge… Leukemia, Lymph…
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NCT01803399
Details
2015-01-28
Interventional
10 
Moxifloxacin
Bacterial Infec… Infections, Bac…
Emerging GSK1322322 pre-clinical data ID'd potentially reactive metabolites previously not seen that changed the risk: benefit profile and led to a termination
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NCT01103713
Details
2015-01-26
Interventional
3168 
Azithromycin Chloroquine
Parasitemia Asymptomatic Pa…
See termination reason in detailed description.
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