Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01488253
Details
2015-04-03
Interventional
23 
MTOR Inhibitors Sirolimus Tacrolimus Temsirolimus
Leukemia Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo… Myelodysplastic… Acute Leukemia … Leukemia, Myelo…
We could not receive the support from the national medical insurance owing to the changed policy of the government for clincal trials.
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NCT01244711
Details
2015-04-03
Interventional
41 
Quetiapine Fuma…
Anxiety Disorde… Depression Depressive Diso… Depressive Diso… Generalized Anx… Major Depressio…
Terminated: recruiting or enrolling participants has halted prematurely
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NCT01203228
NCT00682396
2005-002011-24
Details
2015-04-03
Interventional
3129 
Busulfan Cyclophosphamid… Fludarabine pho…
Myelodysplastic… Secondary Acute…
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NCT00247130
Details
2015-04-03
Interventional
40 
Omeprazole Ranitidine Ranitidine bism…
Peptic Ulcer Ulcer Peptic Ulcers
Superiority of iv omeprazole to ranitidine has already been proven by others.
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NCT00131391
Details
2015-04-03
Interventional
32400 
N-(3-(4-chlorop…
Obesity
The overall profile does not support development for obesity
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NCT01267266
Details
2015-04-01
Interventional
231 
Hydrocortisone Saracatinib
Prostatic Neopl… Hormone-resista… Recurrent Prost… Stage IV Prosta…
Per protocol, study was terminated due to low rate of randomized patients.
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NCT00930345
Details
2015-04-01
Interventional
433 
Sunitinib
Carcinoma Carcinoma, Rena… Metastatic Rena…
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NCT02129400
2014-000973-38
Details
2015-03-31
Interventional
336 
Anesthetics Xenon
Healthy Volunte…
The analysis of the blood samples was much expensive than calculated. The recruitment had to be stopped after 36 study participants.
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NCT01689896
Details
2015-03-31
Interventional
40 
Testosterone
Hypogonadism Low Testosteron… Pain
Difficult to obtain placebo
-
NCT00670956
Details
2015-03-30
Interventional
1/21 
Betamethasone
Congenital Abno… Cystic Adenomat… Congenital Cyst…
Recruitment has been poor. Study drug is being offered as part of standard care of women carrying a pregnancy diagnosed with CCAM
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NCT00254904
Details
2015-03-30
Interventional
3839 
Cisplatin Gemcitabine
Carcinoma, Non-…
See Termination Reason in Detailed Description
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NCT00254891
Details
2015-03-30
Interventional
3828 
Albumin-Bound P… Carboplatin Paclitaxel
Carcinoma, Non-…
See Termination Reason in Detailed Description
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NCT00210392
Details
2015-03-30
Interventional
212 
Bortezomib
Lymphoma Lymphoma, B-Cel… Lymphoma, Mucos…
After IELSG25A study amendment, patients subject of the present study were eligible for inclusion in the IELSG25A study
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NCT02108548
2013-004357-25
Details
2015-03-27
Interventional
189 
Naproxen
Healthy Subject… Pharmacodynamic… Pharmacokinetic…
Gastrointestinal safety findings
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NCT01755702
Details
2015-03-27
Interventional
2/366 
Acetaminophen Caffeine Ibuprofen
Headache Tension-Type He… Headache, Tensi…
Study was terminated due to unforeseen difficulties with subject recruitment. No safety issues were identified in the study with this new formulation.
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NCT00881114
Details
2015-03-27
Interventional
20 
Cetuximab
Head and Neck N… Head and Neck C…
Investigator decided it was not feasible to conduct this study
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NCT00618358
Details
2015-03-27
Interventional
1-
Gelatin Sponge,… Thrombin
Arteriovenous A…
Sponsor - Confluent Surgical terminated study re: surgical techniques Letter dated 4/31/2008
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NCT01440127
Details
2015-03-26
Interventional
19 
Metformin
Colorectal Neop… Colon Cancer
Unable to accrue all planned subjects in a timely fashion, but data collected will still be analyzed.
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NCT00077961
Details
2015-03-26
Interventional
1/2-
Alemtuzumab
Lymphoma Lymphoma, Non-H… Non-Hodgkin's L…
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NCT02398136
Details
2015-03-25
Interventional
2/30 
Ketamine Midazolam
Stress Disorder… PTSD
FDA and IRB recommended different mode of medication administration
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