Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00217464
Details
2015-04-16
Interventional
217 
Fulvestrant
Prostatic Neopl… Prostate Cancer
Closed for futility
-
NCT00003880
Details
2015-04-16
Interventional
2/3132 
Carboplatin Paclitaxel
Ovarian Cancer Primary Periton…
-
-
NCT01851408
Details
2015-04-15
Interventional
20 
MTOR Inhibitors Sirolimus Sorafenib Temsirolimus
Melanoma Recurrence Recurrent Melan… Stage III Melan… Stage IV Melano…
No progression of Phase 1 trial to Phase 2.
-
NCT01235741
Details
2015-04-15
Interventional
2213 
Pramlintide
Obesity
Results from previous study DFA102 demonstrated neutralizing activity to metreleptin in invitro assay in 2 participants.
-
NCT01193491
Details
2015-04-15
Interventional
14 
Geldanamycin
Hematologic Neo… Neoplasms Hematologic Mal…
Drug exposure of retaspimycin HCl was superior to IPI-493, Infinity will focus on Retaspimycin HCL
-
NCT01071564
Details
2015-04-15
Interventional
113 
2,2-dimethyl-N-… Gamma Secretase…
Breast Neoplasm… Carcinoma Estrogen Recept… HER2/Neu Negati… Progesterone Re… Recurrent Breas… Stage IIIB Brea… Stage IIIC Brea… Stage IV Breast… Triple-Negative…
-
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NCT00716469
Details
2015-04-15
Interventional
17 
Talaporfin
Neurofibroma Neurofibroma, P… Neurofibromatos…
The study is terminated due to expiration of study materials.
-
NCT00022542
Details
2015-04-15
Interventional
226 
Epothilone B Epothilones
Sarcoma Recurrent Adult… Stage III Adult… Stage IV Adult …
-
-
NCT01334892
2008-003800-73
Details
2015-04-14
Interventional
2/3130 
Cyclosporine Cyclosporins
Bronchiolitis Bronchiolitis O… Bronchiolitis O…
Interim analysis results revealed substantial increase of patient number, with unfeasible study prolongation.
-
NCT00943553
Details
2015-04-13
Interventional
20 
Decitabine
Leukemia Leukemia, Myelo… Leukemia, Myelo… Acute Myelogeno…
Terminated by Sponsor
-
NCT00081900
Details
2015-04-13
Interventional
1/238 
N(1),N(11)-diet…
Carcinoma Carcinoma, Hepa…
This study was terminated early by Genzyme because there were insufficient data to support clinical benefit to HCC patients on the study.
-
NCT00157508
Details
2015-04-09
Interventional
2-
Nitroaspirin
Diabetes Mellit… Diabetes Mellit… Kidney Diseases Early Nephropat… Type 2 Diabetes
-
-
NCT01714037
Details
2015-04-08
Interventional
182 
Docetaxel Gemcitabine Pemetrexed
Carcinoma, Non-… Lung Neoplasms Non-small Cell …
-
-
NCT01113229
2009-013177-18
Details
2015-04-08
Interventional
41721 
Misoprostol
Hemorrhage Postpartum Hemo… Hemorrhage; Com…
reason of halt prematurely: futility of the trial
-
NCT00885924
Details
2015-04-08
Interventional
417 
Deamino Arginin…
Hemorrhage Postoperative H… Postoperative B…
to include required number of patients took too much time
-
NCT00586976
Details
2015-04-07
Interventional
2/3125 
Ropivacaine
Cardiac Surgery
Stopped by DSMB due to increased wound infection rate.
-
NCT00368719
Details
2015-04-07
Interventional
40 
Tacrolimus
Dermatitis Dermatitis, Ato… Eczema Atopic Dermatit…
withdrawn due to contractual issues
-
NCT00169091
Details
2015-04-07
Interventional
432 
Clozapine Haloperidol Haloperidol dec…
Schizophrenia
-
-
NCT00169039
Details
2015-04-07
Interventional
4-
Chlorpromazine Clozapine
Schizophrenia
-
-
NCT01878864
2012-003430-16
Details
2015-04-03
Interventional
212 
Bupivacaine Lidocaine
Periodontitis Pain and Discom…
Too slow patient inclusion and superior effect of the injection
-