Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01167738
2010-020979-23
Details
2015-04-24
Interventional
260 
Capecitabine Epirubicin Gemcitabine Metformin
Pancreatic Neop… Pancreatic Canc…
concern of detrimental effect
-
NCT01039610
Details
2015-04-22
Interventional
10 
Linezolid Moxifloxacin
Bacterial Infec… Infections, Bac…
Internal decision to progress alternate molecule with more preferable profile
-
NCT01593319
2011-003326-27
Details
2015-04-21
Interventional
4
[5 Refs]
37 
Ropivacaine
Hip Fractures
-
-
NCT01492725
Details
2015-04-21
Interventional
270 
Plasminogen Tissue Plasmino…
Ischemic Stroke
On DSMB advice, trial recruitment has been halted for efficacy. F/U continues
-
NCT01404767
Details
2015-04-21
Interventional
420 
Esmolol Metoprolol
Heart Diseases Vascular Diseas… Angina Cardiac Disease Hypertension Vascular Diseas…
Enrollment slow over 2 years a change in the population less on metoprolol than initially anticipated
-
NCT00832364
Details
2015-04-21
Interventional
40 
Acitretin Etanercept
Psoriasis Plaque Psoriasi…
Business decision. No patients were enrolled
-
NCT00713947
Details
2015-04-21
Interventional
40 
Amoxicillin Clarithromycin Metronidazole Pantoprazole
Coronary Thromb… Thrombosis Positive Helico… Supra-aortic Ar…
no inclusion
-
NCT00361413
Details
2015-04-21
Interventional
326 
Alefacept
Graft vs Host D… Graft Versus Ho…
company withdrawal of the drug
-
NCT00278018
Details
2015-04-21
Interventional
1/2-
Immunomodulatin…
Skin Neoplasms Cancer of Skin Solid Tumors
Because there were no responses
-
NCT00093314
Details
2015-04-21
Interventional
1/20 
Ofatumumab
Leukemia Leukemia, Lymph… Leukemia, Lymph… Chronic Lymphoc…
Acquired asset
-
NCT00092274
Details
2015-04-21
Interventional
1/20 
Ofatumumab
Lymphoma Lymphoma, Folli…
Acquired asset
-
NCT00424775
Details
2015-04-20
Interventional
13 
Vorinostat
Carcinoma, Non-… Lung Neoplasms Neoplasms
-
-
NCT00891761
Details
2015-04-17
Interventional
30 
BB 1101 Casopitant Dexamethasone Dexamethasone a… Ondansetron
Nausea Vomiting Cancer Chemotherapy-In… Nausea and Vomi… Solid Tumor Can…
This study has been cancelled prior to enrollment.
-
NCT00884533
Details
2015-04-17
Interventional
10 
Moxifloxacin
Alzheimer Disea… Alzheimer's Dis…
The whole project was terminated
-
NCT00814372
Details
2015-04-17
Interventional
2242 
Metformin
Diabetes Mellit… Diabetes Mellit… Type 2 Diabetes…
MBX-102 did not meet the target efficacy profile of HbA1c change.
-
NCT00456313
Details
2015-04-17
Interventional
40 
Fluticasone Fluticasone-Sal…
Asthma
lack of data
-
NCT00332319
Details
2015-04-17
Interventional
21 
Casopitant
Enuresis Spinal Cord Inj… Urinary Bladder… Urinary Inconti… Incontinence, U… Overactive Blad…
-
-
NCT00319332
NCT00078676
Details
2015-04-17
Interventional
30 
Tositumomab I-1…
Lymphoma Lymphoma, Folli… Lymphoma, Non-H… Lymphoma, Large… Lymphoma, Small…
This study has been cancelled prior to enrollment
-
NCT01615822
Details
2015-04-16
Interventional
125 
Artefenomel
Malaria
Decision taken to halt progression of mefloquine as a potential partner for OZ439 as a single dose cure due to low probability of success
-
NCT00503763
Details
2015-04-16
Interventional
20 
Simvastatin
Multiple Myelom… Neoplasms, Plas… Smoldering Mult…
We found out that there is another study on the same issue
-