Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01198535
NCT01207882
Details
2015-05-18
Interventional
160 
2,2-dimethyl-N-… Antibodies Antibodies, Mon… Antineoplastic … Cetuximab Gamma Secretase… Immunoglobulins
Adenocarcinoma Adenocarcinoma,… Carcinoma Carcinoma, Sign… Colonic Neoplas… Cystadenocarcin… Rectal Neoplasm… Recurrence Colon Mucinous … Colon Signet Ri… Rectal Mucinous… Rectal Signet R… Recurrent Colon… Recurrent Recta… Stage IVA Colon… Stage IVA Recta… Stage IVB Colon… Stage IVB Recta…
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NCT02036528
Details
2015-05-14
Interventional
1/29 
Ciprofloxacin Doxycycline Gentamicins
Diabetic Foot Foot Ulcer Ulcer Diabetic Foot U…
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NCT00620659
Details
2015-05-13
Interventional
2
[1 Refs]
125 
Modafinil
Apnea Disorders of Ex… Sleep Apnea Syn… Sleep Apnea, Ob… Sleepiness Syndrome Excessive Dayti… Hypopnea Syndro…
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NCT01863225
Details
2015-05-12
Interventional
213 
Atorvastatin Rosuvastatin Ca…
Coronary Artery… Dyslipidemias Dyslipidemia
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NCT00525941
Details
2015-05-12
Interventional
30 
Indiplon
Sleep Initiatio… Insomnia
Study discontinued due to Approvable decision
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NCT01637545
Details
2015-05-08
Interventional
449 
Ramosetron
Facies Fractures, Bone Skull Fractures Facial Bones Fr…
Principal Investigator is away on business
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NCT00666497
Details
2015-05-08
Interventional
26 
Azacitidine Mocetinostat
Leukemia Leukemia, Myelo… Leukemia, Myelo… Myelodysplastic… Preleukemia Syndrome Acute Myeloid L… Myelodysplastic…
Celgene terminated its collaboration agreement with MethylGene for the development of MGCD0103. All Celgene-sponsored trials with MGCD0103 with be closed.
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NCT01496430
Details
2015-05-06
Interventional
3105 
Azilsartan medo…
Diabetes Mellit… Hypertension Diabetes
Business Decision; No Safety Or Efficacy Concerns. (See below)
Because of low enrollment in the study, the sample sizes in the results data do not allow for significant interpretation of the results.
NCT00984152
Details
2015-05-06
Interventional
30 
Efavirenz Efavirenz, Emtr… Raltegravir Pot…
HIV-1 Infection…
Decision not to go forth with study.
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NCT00088907
NCT00695760
Details
2015-05-06
Interventional
3
[1 Refs]
270 
Docetaxel Gefitinib
Head and Neck N… Metastatic Head… Recurrent Head …
It was unlikely that the primary endpoint would be reached based on the fifth interim analysis results.
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NCT01757691
2012-002968-27
Details
2015-05-04
Interventional
22 
Fingolimod Hydr…
Neuritis Optic Neuritis Acute Demylelin…
Discontinuation of this study was based on Novartis decision to discontinue development of fingolimod for the treatment of ADON
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NCT01389856
Details
2015-05-01
Interventional
323 
Bosentan
Hypertension Hypertension, P… Persistent Feta… Persistent Pulm…
To be compliant with the timelines as agreed with Paediatric Committee (PC) within the Paediatric Investigational Plan
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NCT00395967
Details
2015-05-01
Interventional
25 
Plerixafor
Lymphoma Lymphoma, Non-H… Multiple Myelom… Neoplasms, Plas… Lymphoma, Non-H…
Enrollment terminated in 2005 to focus on Phase 3 study enrollment.
Limited enrollment due to early termination of the study.
NCT00109538
Details
2015-05-01
Interventional
347 
Lonafarnib
Leukemia Leukemia, Myelo… Leukemia, Myelo… Myelodysplastic… Preleukemia Syndrome Myelodysplasia Myelomonocytic
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NCT01148901
2009-016587-36
Details
2015-04-30
Interventional
40 
Infliximab
Arthritis Spondylarthriti… Spondylitis Spondylitis, An… Ankylosing Spon…
No patient enrolled after 6 months from the start. The decision to withdraw the study was based on a feasibility reevaluation conducted with investigators.
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NCT02213653
Details
2015-04-29
Interventional
424 
Iron
Anemia, Iron-De… Iron Deficienci… Neoplasm Metast… Lymphoid Diseas… Solid Cancer Me…
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NCT00459901
Details
2015-04-29
Interventional
213 
Capecitabine Erlotinib Hydro…
Colorectal Neop… Metastatic Colo…
Study halted by drug manufacturer
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NCT01981811
Details
2015-04-28
Interventional
20 
Aripiprazole
Mental Disorder… Nervous System … Schizophrenia Bipolar 1 Disor… Mental Disorder
The trial was terminated because it was determined that the usability of the MIND1 System in the intended population was necessary before conducting this trial.
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NCT01561404
2009-010541-31
Details
2015-04-28
Interventional
43 
Everolimus
Disorder Relate… Exercise, Aerob… Muscle Strength
lack of potential patients
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NCT00385450
Details
2015-04-28
Interventional
141 
Nelfinavir
Lymphopenia Cardiopulmonary…
Study closed at Mayo prior to completion
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