Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

Filter:

Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
Free Text
Annotations

7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00770770
Details
2015-05-28
Interventional
220 
Fluocinolone Ac…
Edema Macular Edema Retinal Vein Oc…
-
-
NCT00717808
2007-005357-39
Details
2015-05-28
Interventional
10 
Anthranilic aci… Tranilast
Arthritis Arthritis, Rheu… Rheumatoid Arth…
Due to unforeseen circumstances this study will not now start.
-
NCT00100152
Details
2015-05-27
Interventional
1-
3-(4-((4-chloro…
Leukemia Leukemia, Lymph… Leukemia, Myelo… Myelodysplastic… Precursor Cell … Precursor T-Cel… Chronic Lymphoc… Leukemia, Lymph… Myelogenous Leu…
-
-
NCT01701466
NCT01470872
Details
2015-05-25
Interventional
214 
Silver Sulfadia…
Dermatitis Radiodermatitis Breast Cancer Head and Neck C…
-
-
NCT01687751
Details
2015-05-25
Interventional
20 
Dexmedetomidine Midazolam
Delirium Dyspnea Nausea Pain Intractabl…
Study design determined to be not likely feasible
-
NCT01149356
Details
2015-05-25
Interventional
115 
2,2-dimethyl-N-… Exemestane Gamma Secretase… Goserelin
Breast Neoplasm… Breast Neoplasm… Carcinoma Estrogen Recept… HER2/Neu Negati… Male Breast Car… Recurrent Breas… Stage IIIB Brea… Stage IIIC Brea… Stage IV Breast…
Manufacturer discontinued drug development.
-
NCT01861990
Details
2015-05-22
Interventional
10 
Valproic Acid
Astrocytoma Brain Neoplasms Glioblastoma Medulloblastoma Anaplastic Astr… Glioma Pediatric Brain…
Feasibility of the trial was proven to be absent.
-
NCT00735241
Details
2015-05-22
Interventional
2/30 
Bevacizumab Fluorouracil Folic Acid Leucovorin Levoleucovorin Oxaliplatin
Carcinoma Colorectal Neop… Liver Neoplasms Neoplasm Metast… Colorectal Carc… Liver Metastase…
Withdrawn by the study sponsor.
-
NCT02176057
Details
2015-05-21
Interventional
2/30 
Azithromycin
Trachoma
Nepal Ministry of Health implemented public drug treatment prior to the proposed start date
-
NCT01576640
Details
2015-05-21
Interventional
417 
Bupropion
Schizophrenia Tobacco Use Dis… Nicotine Depend…
-
-
NCT01038752
Details
2015-05-21
Interventional
214 
Carboplatin Docetaxel Suramin
Carcinoma, Non-… Lung Neoplasms Non-small Cell …
-
The study was terminated prematurely due to the loss of follow-up of 6 of 14 participants before progression and slow accrual. Due to the resulting small numbers, no analysis was attempted.
NCT00936923
Details
2015-05-21
Interventional
30 
Diuretics Furosemide
Renal Function …
The study was withdrawn prior to enrollment of first participant.
-
NCT00750334
Details
2015-05-21
Interventional
12 
Clofarabine
Myelodysplastic… Preleukemia Syndrome
Terminated to focus on comparable trial, CLOMDS02507
-
NCT01218009
Details
2015-05-20
Interventional
3331 
Albuterol
Asthma
Change to study required.
-
NCT01480791
Details
2015-05-19
Interventional
20 
Aliskiren Hydrochlorothia…
Hypertension Diabetes
Because of results of Altitude trial, this trial was cancelled.
-
NCT01436123
Details
2015-05-19
Interventional
162 
Everolimus
Atherosclerosis Coronary Artery…
The study was terminated under the political pressure of the Federal Security Service of the Russian Federation (FSB) and the Russian Society of Cardiology
-
NCT01319188
Details
2015-05-19
Interventional
4380 
Ranibizumab
Cerebrovascular… Coronary Artery… Coronary Diseas… Macular Degener… Myocardial Isch… Thromboembolism Age-related Mac…
The study was terminated under the political pressure of the Federal Security Service of the Russian Federation (FSB) and the Russian Society of Cardiology
-
NCT01158703
Details
2015-05-19
Interventional
420 
Aspirin Clopidogrel
Coronary Graft …
poor recruitment and reduction in CT surgery support
The study did not recruit enough patients due to strict exclusion criteria and low volume of consenting patients resulting in a sample size that was insufficient for power analysis.
NCT00420797
Details
2015-05-19
Interventional
30 
Oxymetazoline Phenylephrine
Fecal Incontine… Faecal Incontin…
Terminated, new protocol to be developed
-
NCT00388388
Details
2015-05-19
Interventional
21 
Hydrochlorothia… Losartan
Prediabetic Sta… Prehypertension Pre-diabetes Pre-hypertensio…
Few subjects recruited, sponsor withdrew support.
-