Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01530984
Details
2015-10-05
Interventional
20 
Ipilimumab Sargramostim
Prostatic Neopl… Prostate Cancer
Unable to execute contract
-
NCT02316249
Details
2015-10-02
Interventional
20 
Estradiol
Atrophy Pelvic Organ Pr… Ulcer Vaginitis Atrophy of Vagi… Vaginal Ulcerat…
the study was not feasible
-
NCT01911377
Details
2015-10-02
Interventional
212 
Botulinum Toxin… Botulinum Toxin… abobotulinumtox…
Hyperalgesia Neuralgia Allodynia Neuropathic Pai…
12 SCI volunteers completed the study. As the data analysis was negative, the decision was made not to proceed with MS recruitment.
-
NCT01426113
Details
2015-10-02
Interventional
36 
Bimatoprost Ophthalmic Solu… Pharmaceutical … Timolol
Glaucoma
Study terminated due to corporate decision.
-
NCT01004419
Details
2015-10-02
Interventional
10 
Fulvestrant
Carcinoma, Non-… Lung Neoplasms Carcinoma, Non …
Support for investigational products has been withdrawn.
-
NCT00518687
Details
2015-10-02
Interventional
2/38031 
Vaccines
Bacteremia Mediastinitis Staphylococcus …
-
-
NCT01930877
Details
2015-10-01
Interventional
20 
Lidocaine
Pain
Withdrawn by PI
-
NCT00923117
NCT00713388
Details
2015-09-30
Interventional
287 
Sunitinib
Glioblastoma Glioma Anaplastic Glio… Glioblastoma Mu… Malignant Gliom…
The study was terminated based on results of an interim analysis for futility.
The study was terminated based on results of an interim analysis for futility.
NCT00411281
Details
2015-09-30
Interventional
30 
Cytarabine
Down Syndrome Leukemoid React… Myeloproliferat… Leukemia
Per Group Chair: This study will not move forward.
-
NCT00384293
Details
2015-09-30
Interventional
3937 
Niacin
Hypercholestero… Hyperlipoprotei… Hypercholestero…
-
After a detailed review of pooled carotid IMT data from contemporary studies, the Steering Committee recommended that Merck prematurely stop the study; as designed, the study was significantly underpowered. Efficacy analyses were not performed.
NCT01625741
Details
2015-09-29
Interventional
26 
Rituximab
Leukemia Leukemia, Lymph… Leukemia, Lymph… Chronic Lymphoc…
Stopped by Principal Investigator decision
-
NCT01193881
Details
2015-09-29
Interventional
116 
2,2-dimethyl-N-… Erlotinib Hydro… Gamma Secretase…
Carcinoma, Non-… Lung Neoplasms Recurrent Non-S… Stage IV Non-Sm…
-
-
NCT00873886
Details
2015-09-29
Interventional
10 
Oseltamivir
Influenza Pregnancy
We will focus on other Tamiflu research studies. No subjects were enrolled.
-
NCT01834274
2013-000542-19
Details
2015-09-28
Interventional
396 
Metformin Sitagliptin Pho…
Diabetes Mellit… Diabetes Mellit…
Due to potential concerns about liver safety (See Detailed Description)
-
NCT01598584
Details
2015-09-28
Interventional
2/30 
Gemcitabine Mirtazapine
Pancreatic Neop… Pancreatic Canc…
Gemcitabine is not the first choice for most pancreatic cancer patients nowdays
-
NCT00298272
Details
2015-09-28
Interventional
2
[1 Refs]
54 
Adalimumab Etanercept Methotrexate Methylprednisol… Rituximab
Arthritis Arthritis, Rheu… Rheumatoid Arth…
Sponsor decided to end long term extension phase for business reasons unrelated to safety.
Sponsor made a business decision to terminate study on 28 July 2011, after completion of the primary endpoint and during the long-term extension phase. One participant was still in extended safety follow-up and was referred for appropriate care.
NCT02150161
Details
2015-09-25
Interventional
353 
Fentanyl Ketamine Lidocaine
Opioid Free Ana… Postoperative A…
DSMB estimated futility of the trial and safety risk
-
NCT01734824
Details
2015-09-23
Interventional
4-
Denosumab Parathyroid Hor… Teriparatide
Bone Diseases Edema Bone Marrow Oed… High Turnover B… Quality of Life
no patients randomized
-
NCT00377780
Details
2015-09-23
Interventional
260 
Docetaxel Doxorubicin Liposomal doxor… Trastuzumab
Breast Neoplasm… Neoplasm Metast… Breast Cancer
wothdrawal of sponsor
-
NCT00056979
Details
2015-09-23
Interventional
1/22 
Alemtuzumab Fludarabine
Metabolic Disea… Inherited Metab…
-
-