Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01809171
2013-001064-27
Details
2015-10-21
Interventional
2/315 
Cholecalciferol Vitamin D
Breast Neoplasm… Musculoskeletal… Breast Cancer Musculoskeletal…
Inclusion problems
-
NCT01042028
Details
2015-10-20
Interventional
1/239 
Capecitabine Cetuximab Everolimus Irinotecan Oxaliplatin
Pancreatic Neop… Pancreatic Canc…
Emergence of FOLFIRINOX and slow recruitment
-
NCT00272909
Details
2015-10-20
Interventional
243 
Piclozotan
Ischemic Stroke Stroke
-
-
NCT00437073
Details
2015-10-15
Interventional
222 
Capecitabine Lapatinib Topotecan
Brain Neoplasms Breast Neoplasm… Neoplasm Metast… Neoplasms, Brea…
Lapatinib-topotecan arm enrollment closed early per protocol amendment 2. Then enrollment into remaining arm terminated due to operational issues.
-
NCT00428168
Details
2015-10-15
Interventional
236 
Betahistine
Body Weight Weight Gain
Interim Analysis result indicated the study will not show a significant benefit of the study medication on the primary endpoint.
-
NCT00360867
Details
2015-10-15
Interventional
294 
Imetelstat Motesanib dipho…
Solid Tumors
Amgen decision
-
NCT00356681
Details
2015-10-15
Interventional
2282 
Bevacizumab Imetelstat Motesanib dipho… Niacinamide Paclitaxel
Breast Neoplasm… Breast Cancer Breast Tumors Locally Recurre…
Sponsor decision to close study
-
NCT00031837
Details
2015-10-14
Interventional
3-
Dalteparin Gemcitabine Heparin, Low-Mo… Tinzaparin
Pancreatic Neop… Thromboembolism Pancreatic Canc…
-
-
NCT02197286
Details
2015-10-12
Interventional
20 
Cholecalciferol Ergocalciferols Vitamin D Vitamins
Psychotic Disor… Schizophrenia Schizoaffective…
Personnel changes at study site.
-
NCT01546883
Details
2015-10-12
Interventional
414 
Dabigatran
Atrial Fibrilla…
Not enough patients in time period allotted for study
-
NCT00890890
2009-010067-16
Details
2015-10-12
Interventional
2263 
BMS 708163
Alzheimer Disea… Alzheimer's Dis…
-
-
NCT00850577
2008-007768-41
Details
2015-10-12
Interventional
2255 
Bevacizumab Carboplatin Paclitaxel Pharmaceutical …
Carcinoma, Non-… Lung Neoplasms Non-small Cell …
-
-
NCT00805311
Details
2015-10-12
Interventional
4
[1 Refs]
400 
Amlodipine Aspirin Atorvastatin Losartan
Atherosclerosis Carotid Stenosi… Constriction, P… Carotid Artery … Stroke
Due to the clear advantage of carotid endarterectomy
-
NCT01868243
Details
2015-10-09
Interventional
2/327 
Dabigatran Warfarin
Atrial Fibrilla… Primary Disease
because a significant decrease of viable candidates for the study.
-
NCT01751802
Details
2015-10-08
Interventional
39 
Ecopipam
Lesch-Nyhan Syn… Self-Injurious … Lesch-Nyhan Dis… Self-injurious …
Study terminated for commercial reasons
-
NCT00591019
Details
2015-10-08
Interventional
17 
Modafinil
Tinnitus
Terminated early due to lack of change in primary and secondary outcome measures.
Study was terminated early due to lack of change in primary and secondary outcome measures.
NCT00469976
Details
2015-10-08
Interventional
20 
Bevacizumab Carboplatin Gemcitabine
Carcinoma, Non-… Lung Neoplasms Lung Cancer
ECOG will not proceed with activation
-
NCT01887457
2013-002578-34
Details
2015-10-07
Interventional
2-
Voriconazole
Aspergillosis Fusarium Immunocompromis…
Transfer of management of study
-
NCT02307591
Details
2015-10-06
Interventional
2/30 
Amiodarone
Hemorrhagic Fev… Virus Diseases Ebola Virus Dis…
The Study could not be started due to an insufficient number of new EVD cases.
-
NCT00093652
Details
2015-10-06
Interventional
1/2
[1 Refs]
-
Gefitinib Oxaliplatin
Esophageal Neop… Esophageal Canc…
-
-