Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00871442
Details
2015-11-18
Interventional
30 
Anesthetics Bupivacaine Fentanyl
Labor Pain
would not substantially add to existing contributions in the literature
-
NCT02023047
Details
2015-11-17
Interventional
1/233 
Nifedipine
Fissure in Ano Anal Fissure
Met primary endpoint
-
NCT01549847
Details
2015-11-17
Interventional
30 
Piracetam
Muscle Weakness Myalgia Postpoliomyelit… Syndrome
Study was not approved by Health Surveillance Agency
-
NCT01527097
Details
2015-11-17
Interventional
30 
Atorvastatin
Psoriasis
We strongly feel that the ability to recruit the required number of patients is very low and thus decided to stop the study.
-
NCT01211691
Details
2015-11-17
Interventional
1/2-
Antibodies Antibodies, Mon…
Hematologic Neo… Myelodysplastic… Neoplasms Preleukemia Primary Myelofi… Syndrome Myelodysplastic… Myelofibrosis (…
KaloBios to Wind Down Operations
-
NCT01050933
Details
2015-11-17
Interventional
110 
Carbon Monoxide
Healthy
resident left and no one to take over
-
NCT01050712
Details
2015-11-17
Interventional
23 
Carbon Monoxide
Ileus
According to retired PI, resident graduated and next resident never carried it to fruition.
-
NCT01878136
Details
2015-11-11
Interventional
1/20 
Plasminogen Tissue Plasmino…
Aneurysm Hemorrhage Hydrocephalus Intracranial An… Subarachnoid He… Vasospasm, Intr… Cerebral Aneury… Cerebral Vasosp…
Time constraints
-
NCT01076556
Details
2015-11-11
Interventional
19 
Alvocidib Antibodies Antibodies, Mon… Antineoplastic … Cyclophosphamid… Immunoglobulins Rituximab
Leukemia Leukemia, Lymph… Leukemia, Lymph… Leukemia, Proly… Lymphoma Chronic Lymphoc… Prolymphocytic … Recurrent Small… Refractory Chro… Stage I Chronic… Stage I Small L… Stage II Chroni… Stage II Small … Stage III Chron… Stage III Small… Stage IV Chroni… Stage IV Small …
-
-
NCT00838578
Details
2015-11-11
Interventional
1/265 
Irinotecan
Colorectal Neop… Colorectal Canc…
Per protocol, the study was terminated based on interim analysis results
-
NCT01458639
Details
2015-11-10
Interventional
318 
Xenon
Embolism Pulmonary Embol…
Decision to change trial design.
PE adjudication by Independent Committee for final clinical diagnosis and blinded readings of Xe-133 and Technegas Ventilation and Tc-99m MAA Perfusion images were not performed due to early trial termination. No efficacy data available.
NCT00533390
Details
2015-11-10
Interventional
4130 
Efavirenz
Tuberculosis HIV Infections
Lack of financial support and low inclusion rate
-
NCT01497197
Details
2015-11-09
Interventional
3174 
Chorionic Gonad…
Infertility Fertility Follicle Stimul…
Study was terminated as per sponsor's decision
Study was terminated as per sponsor's decision.
NCT02599090
Details
2015-11-06
Interventional
20 
Sorafenib Temozolomide
Glioblastoma Gliosarcoma
Multi phase study did not progress to Phase II. Phase I registered as NCT00734526.
-
NCT01348126
Details
2015-11-05
Interventional
2/3385 
Docetaxel
Carcinoma, Non-… Lung Neoplasms Non-small Cell … Non-small Cell … Non-small Cell …
-
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NCT01032915
2009-014835-19
Details
2015-11-05
Interventional
3125 
Antibodies, Mon…
Uveitis Non-infectious …
Results of a planned interim analysis did not show significant effects for any of the 3 AIN dose regimens versus placebo on any primary or secondary endpoint
-
NCT01425970
Details
2015-11-04
Interventional
2210 
Interferon alph… Interferon-alph… Interferons Peginterferon a… Ribavirin
Hepatitis Hepatitis C
Termination of study was due to safety reasons
-
NCT01256489
Details
2015-11-04
Interventional
1/20 
Infliximab
Blindness Stevens-Johnson… Syndrome Corneal Blindne…
Steven Johnson's Syndrome (SJS) and Toxic Epidermal Necrolysis Syndrome (TENS) are rare (~3 in 1 million). No eligible subjects have been identified.
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NCT01056757
Details
2015-11-04
Interventional
1/24 
Ribavirin
Breast Neoplasm… Metastatic Brea…
Study closed because of new overlapping study with ribavirin.
-
NCT00763893
2006-006112-30
Details
2015-11-04
Interventional
3
[2 Refs]
303 
Losartan
Arachnodactyly Marfan Syndrome Syndrome
A similar publication has been released, suggesting a beneficial effect of sartans, and only 15 patients remained to be seen for their visit at 36 months.
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