Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00040157
Details
2015-12-30
Interventional
2-
Dexelvucitabine
Acquired Immuno… HIV Infections Infections
Safety concerns
-
NCT01893385
2012-005658-52
Details
2015-12-23
Interventional
237 
Vitamin D
Avitaminosis Vitamin D Defic… D Vitamin Defic…
-
-
NCT01624493
Details
2015-12-23
Interventional
1/20 
Carboplatin Gemcitabine
Carcinoma, Ovar… Hypersensitivit… Ovarian Neoplas… Ovarian Cancer
Phase I was conducted Australia. Phase II not conducted and no US pts enrolled.
-
NCT01802593
Details
2015-12-22
Interventional
420 
Azathioprine Mercaptopurine Methotrexate
Crohn Disease Crohn's Disease
lack of budget and failure to reach milestones
-
NCT00986284
Details
2015-12-22
Interventional
2102 
Gefitinib
Carcinoma, Non-… Lung Neoplasms Non Small Cell …
Lack of patients and some progressed disease soon after surgery
-
NCT00866281
2008-006931-11
Details
2015-12-22
Interventional
1/222 
Midostaurin
Leukemia Leukemia, Lymph… Leukemia, Myelo… Leukemia, Myelo… Precursor Cell … Acute Lymphobla… Acute Myeloid L…
Despite considerable efforts to boost recruitment during the final year of the study, no new patients were enrolled.
The study was terminated early since despite considerable efforts to boost recruitment, no new participants were enrolled in the final year of this study.
NCT01303250
2009-017595-25
Details
2015-12-18
Interventional
431 
Hydroxyethyl St…
Surgery, Colore…
The final decision of the review of HES-containing solution shall be awaited.
-
NCT01021176
Details
2015-12-18
Interventional
112 
Diltiazem
Food Intake
-
-
NCT00517582
Details
2015-12-18
Interventional
113 
Icatibant
Angioedema Angioneurotic E…
This study was stopped to allow initiation of a mult-center study
-
NCT00272025
Details
2015-12-16
Interventional
11 
Escitalopram
Bipolar Disorde… Depression Depressive Diso… Bipolar Depress…
Lundbeck withdrew committment - expiring patents and prolonged inactivity
-
NCT01880437
2013-001570-14
Details
2015-12-15
Interventional
238 
Cytarabine
Leukemia Leukemia, Myelo… Leukemia, Myelo… Myelodysplastic… Preleukemia Syndrome Myelodysplastic…
-
This study was prematurely terminated because of lower-than-expected efficacy observed in interim data analyses.
NCT01705808
Details
2015-12-15
Interventional
3-
Protein C
Critical Illnes… Sepsis
-
-
NCT02629848
Details
2015-12-14
Interventional
3401 
Carboplatin Motesanib dipho… Paclitaxel
Carcinoma, Non-…
Sponsor decision to terminate the study because the study did not meet the primary endpoint.
-
NCT00047567
Details
2015-12-14
Interventional
4-
Zonisamide
Bipolar Disorde… Bipolar Disorde…
-
-
NCT02357732
Details
2015-12-11
Interventional
10 
Dabrafenib Nivolumab Trametinib
Melanoma Metastatic Mela…
PI decided not to proceed
-
NCT02281292
Details
2015-12-11
Interventional
10 
Ophthalmic Solu… Pharmaceutical … Ranibizumab
Edema Macular Edema Diabetic Macula…
Management Decision
-
NCT00636441
Details
2015-12-11
Interventional
256 
Cyclophosphamid… Docetaxel Doxorubicin Liposomal doxor…
Breast Neoplasm… Early-Stage Bre…
Study terminated due to reproducibility issues with genomics prediction model
-
NCT01675947
NCT01664208
Details
2015-12-10
Interventional
252 
Lidocaine Sirolimus
Atrophy Geographic Atro…
On May 30, 2014, study injections were discontinued at the request of the DSMC. No further recruitment will occur.
-
NCT01530399
Details
2015-12-10
Interventional
244 
Tranexamic Acid
Bleeding
Safety
-
NCT01260467
Details
2015-12-10
Interventional
24 
Memantine
Glioblastoma
-
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