Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00910273
Details
2016-01-13
Interventional
434 
Etanercept
Spondylarthriti… Spondylitis Spondylitis, An… Ankylosing Spon…
-
Due to early termination and few participants attending visits after Week 12, statistical analysis limited to Week 12.
NCT00673361
Details
2016-01-13
Interventional
29 
Sorafenib Temozolomide
Melanoma
-
-
NCT01093092
Details
2016-01-12
Interventional
114 
Calcitriol Dihydroxycholec… Gemcitabine
Adult Solid Neo…
Study transferring to INOVA Health
-
NCT00718523
Details
2016-01-12
Interventional
2170 
Antibodies, Mon…
Carcinoma, Ovar… Ovarian Neoplas…
The steering committee of the TRIO014 study has taken the decision to stop the TRIO014 trial.
-
NCT02229240
Details
2016-01-11
Interventional
30 
Glucagon-Like P… rGLP-1 protein
Diabetes Mellit… Diabetes Mellit…
Study was cancelled prior to enrolling any patients
-
NCT00387777
2006-003177-27
Details
2016-01-11
Interventional
1-
Analgesics Buprenorphine
Healthy
-
-
NCT00364429
Details
2016-01-11
Interventional
155 
Lorazepam Risperidone
Schizophrenia
terminated
-
NCT02144246
Details
2016-01-08
Interventional
15 
Estradiol Estradiol 17 be… Estradiol 3-ben… Ethinyl Estradi… Moxifloxacin Norgestimate Norgestimate, e… Norgestrel Polyestradiol p…
Cystic Fibrosis Fibrosis Cystic Fibrosis…
-
-
NCT01927055
Details
2016-01-08
Interventional
361 
Droxidopa Mannitol
Hypotension Hypotension, Or… Multiple System… Parkinson Disea… Pure Autonomic … Shy-Drager Synd… Dopamine Beta H… Multiple System… Parkinson's Dis… Symptomatic Neu…
Due to potential competition with a post-marketing study requested by FDA
The study was prematurely terminated; the limited sample size precludes meaningful conclusions on the efficacy or safety of droxidopa in this study.
NCT01546688
2006-002516-10
Details
2016-01-08
Interventional
441 
Zonisamide
Seizures Epilepsy
-
-
NCT00984217
Details
2016-01-08
Interventional
20 
Panitumumab
Adenoma Adenoma, Pleomo… Neoplasms Salivary Gland … Syringoma Mixed Salivary … Salivary Gland … Syringoma, Chon…
Decided not to pursue at UPCI
-
NCT02409433
Details
2016-01-07
Interventional
43 
Lacosamide Phenytoin
Seizures
due to slow recruitment and budgetary restraints study was prematurely terminated
-
NCT00022490
Details
2016-01-07
Interventional
224 
Cytarabine Imatinib Mesyla…
Leukemia Leukemia, Myelo… Leukemia, Myelo…
-
Study was terminated, therefore the 12 month response data was not analyzed.
NCT02532192
Details
2016-01-06
Interventional
10 
Belinostat Ciprofloxacin Cisplatin Cytarabine Dexamethasone Fluconazole Rituximab
Lymphoma Lymphoma, B-Cel… Lymphoma, Large…
Withdrawal of study support.
-
NCT02324491
Details
2016-01-06
Interventional
2152 
CKD732
Diabetes Mellit… Diabetes Mellit… Obesity Type 2 Diabetes
Sponsor decision to analyze available safety and efficacy data
-
NCT01510847
Details
2016-01-06
Interventional
419 
Testosterone un…
Assess the Effe…
Unable to reach the target recruitment within timeline
-
NCT01420666
Details
2016-01-06
Interventional
30 
Acetaminophen Ibuprofen
Osteoarthritis
The study was withdrawn for administrative reason
-
NCT00492531
Details
2016-01-06
Interventional
274 
Phosphodiestera… Sildenafil Citr…
Anemia, Sickle … Hypertension Hypertension, P… Pulmonary Hyper… Sickle Cell Dis…
Subjects on drug were more likely to have severe pain crises requiring hospitalization.
As a result of early termination due to safety findings, the study was underpowered to assess the effects of sildenafil therapy on the predetermined efficacy endpoints.
NCT00421317
Details
2016-01-06
Interventional
213 
Imatinib Mesyla…
Melanoma
Study stopped at the end of the first step
-
NCT01067274
Details
2015-12-30
Interventional
30 
Azacitidine Cytarabine Tretinoin
Leukemia Leukemia, Myelo… Leukemia, Myelo… Acute Myeloid L…
Study abandoned
-