Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00440973
Details
2016-03-17
Interventional
26 
Bevacizumab Interleukin-2
Carcinoma Carcinoma, Rena…
contract issues
-
NCT02144688
NCT01848678
Details
2016-03-16
Interventional
119 
Anti-Retroviral…
Acquired Immuno… HIV Infections Immunologic Def… Neurobehavioral… Cognitive Sympt… HIV - Human Imm…
In 14 participants who had LP, very low level viremia was found in only 1
-
NCT01726920
Details
2016-03-16
Interventional
30 
Naproxen Naratriptan
Headache Migraine Disord… Migraine
Due to budget limitations, the company decided to withdraw this study.
-
NCT02351310
Details
2016-03-14
Interventional
30 
Betamethasone
Obstetric Labor… Premature Birth Preterm Labor
Company decided not to pursue this study.
-
NCT01032759
Details
2016-03-14
Interventional
477 
Memantine
Pain
-
-
NCT00585156
Details
2016-03-14
Interventional
19 
Celecoxib
Bone Ingrowth Pain
New clinical finding with Celebrex and cardiac concerns.
-
NCT01974700
Details
2016-03-11
Interventional
417 
Levetiracetam
Aneurysm Intracranial An… Seizures Intracranial An…
Lack of enrollment - since the start of the study in 2013, only 17 subjects have consented. Of those, only 8 completed the study.
-
NCT01730157
Details
2016-03-10
Interventional
16 
Antibodies Antibodies, Mon… Antineoplastic … Immunoglobulins Ipilimumab
Melanoma Neoplasm Metast… Uveal Neoplasms Ciliary Body an… Ciliary Body an… Extraocular Ext… Iris Melanoma Liver Metastase… Metastatic Intr… Recurrent Intra… Stage IV Intrao…
Research Cancelled
-
NCT02156843
2014-001641-24
Details
2016-03-09
Interventional
3328 
Pyridoxamine
Diabetic Nephro… Kidney Diseases Diabetic Kidney… Diabetic Nephro…
-
-
NCT02296671
Details
2016-03-08
Interventional
20 
Fluorouracil Leucovorin Oxaliplatin Pemetrexed
Esophagogastric…
Was unable to accrue any patients
-
NCT01836614
Details
2016-03-08
Interventional
1/20 
Lidocaine
Pain, Postopera… Colorectal Diso…
Study was closed due to recommendations of performing a PK study first.
-
NCT01705496
Details
2016-03-07
Interventional
223 
Fialuridine
Prosthetic Join…
The sensitivity and specificity were not able to be assessed in this study due to the poor image quality.
-
NCT00318474
Details
2016-03-07
Interventional
3184 
Angiotensin-Con… Enzyme Inhibito… Mycophenolic Ac…
Glomerulonephri… Kidney Diseases IgA Nephropathy
DSMB recommended stopping the trial because of lack of effect.
-
NCT01441193
Details
2016-03-04
Interventional
111 
Vaccines
HIV Infections HIV Infection
Enrollments were suspended due to delta-V2 Env unavailability, following the EMA/CHMP/BWP/534898/2008 guideline, not allowing the use of a retest date
-
NCT01353937
Details
2016-03-04
Interventional
10 
Becaplermin Plerixafor
Diabetic Foot Foot Ulcer Ulcer Diabetic Ulcer
Never Activated
-
NCT00348634
Details
2016-03-04
Interventional
4-
Tegaserod
Constipation Chronic Constip…
Terminated early due to regulatory action suspending tegaserod use in 2007
-
NCT01906307
Details
2016-03-03
Interventional
16 
Angiotensin II Giapreza
Hepatorenal Syn… Syndrome Hepatorenal Syn…
Corporate decision
-
NCT01026961
Details
2016-03-03
Interventional
1/20 
Acetaminophen Dimethindene Oxymetazoline Phenylephrine
Arrhythmias, Ca… Arrhythmias Blood Pressure Heart Rate
Study is no longer required by Brazil health authority.
-
NCT02179099
Details
2016-03-01
Interventional
1/23 
Botulinum Toxin… Botulinum Toxin…
Urinary Bladder… Overactive Blad…
Decision to open a randomized controlled trial with two groups receiving different Botulinum Toxin in comparison to placebo group.
-
NCT01615185
Details
2016-03-01
Interventional
4
[4 Refs]
96 
Amisulpride
Schizophrenia
-
-