Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

Filter:

Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
Free Text
Annotations

7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00578903
NCT00598221
Details
2016-04-22
Interventional
222 
Alemtuzumab Cyclophosphamid… Methotrexate Tacrolimus
Anemia Anemia, Aplasti… Aplastic Anemia
-
-
NCT02598687
Details
2016-04-21
Interventional
10 
Carboplatin Paclitaxel
Esophageal Neop… Esophageal Canc…
2 Phase 3 trials didn't meet their primary endpoint, so further development and testing of TH-302 is uncertain
-
NCT02349828
Details
2016-04-21
Interventional
2/30 
Acyclovir
Herpes Simplex
PI decided to stop due to divisional reorganization. No pts enrolled.
-
NCT00973193
Details
2016-04-20
Interventional
220 
Panitumumab
Rectal Neoplasm… Rectal Cancer
The intermediate analyses did not allowed to continue the clinical study.
-
NCT00523120
Details
2016-04-20
Interventional
220 
Diclofenac
Otitis Otitis Externa
-
-
NCT01762657
Details
2016-04-19
Interventional
30 
Cyclosporine Cyclosporins Dexlansoprazole Lansoprazole
Diabetes Mellit… Diabetes Mellit… Type 1 Diabetes
Study stopped prior to Patient Enrollment
-
NCT01563614
Details
2016-04-19
Interventional
11 
Cytarabine Lomustine
Melanoma Meningeal Carci… Neoplasm Metast… Leptomeningeal …
No patients can be recruited for this trial anymore due to other therapeutical approaches that became available.
-
NCT01045876
Details
2016-04-19
Interventional
40 
Dexamethasone
Adrenal Insuffi…
Lack of resources
-
NCT00510289
Details
2016-04-19
Interventional
219 
Sorafenib
Leukemia, Myelo… Myelodysplastic… Preleukemia Syndrome
Early closure of study due to poor response
The limitations of our study include the small sample size, the poor toxicity profile and the lack of response.
NCT00287326
Details
2016-04-19
Interventional
3-
Bupivacaine Clonidine Morphine
Pain
terminated by PI
-
NCT01955629
2013-000858-22
Details
2016-04-18
Interventional
1/24 
Aflibercept Capecitabine Oxaliplatin
Colorectal Neop… Colorectal Canc…
The study enrollment was prematurely halted due to safety reasons.
The study enrollment was prematurely halted due to safety reasons.
NCT01762644
2015-000105-39
Details
2016-04-18
Interventional
30 
Cyclosporine Cyclosporins Omeprazole
Diabetes Mellit… Diabetes Mellit… Type 1 Diabetes
This study was withdrawn prior to enrollment.
-
NCT02190526
Details
2016-04-15
Interventional
40 
Amitriptyline Mesalamine
Diarrhea Irritable Bowel… Syndrome Diarrhea- Predo… Quality of Life
Study stopped due to lack of volunteer patients.
-
NCT01578343
Details
2016-04-15
Interventional
220 
BB 1101 Dexamethasone Dexamethasone a… Fludarabine Fludarabine pho… Mitoxantrone Vorinostat
Lymphoma Lymphoma, Mantl… Mantle Cell Lym…
we collected data of a total of 19 patients for an interim analysis. but there are less than 7 responses out of the initial 19 patients.
-
NCT01489046
2011-003329-89
Details
2016-04-15
Interventional
2297 
Efavirenz Lamivudine Tenofovir
Infections HIV-1 Infection
-
-
NCT02479178
Details
2016-04-14
Interventional
273 
Docetaxel
Carcinoma Carcinoma, Squa… Carcinoma, Tran… Cholangiocarcin… Squamous Cell C… Uterine Cervica… Cervical Cancer Urothelial Carc…
-
-
NCT01765803
Details
2016-04-14
Interventional
16 
Thioridazine
Healthy Subject…
Primary objective not met after planned interim analysis
-
NCT02428218
2014-005624-98
Details
2016-04-13
Interventional
30 
Dimethyl Fumara…
Multiple Sclero… Multiple Sclero… Sclerosis Relapsing Forms… Relapsing-Remit…
Feasibility
-
NCT01670071
Details
2016-04-13
Interventional
417 
Paliperidone Pa… Risperidone
Schizophrenia
The study was terminated due to insufficient sample size and protocol compliance issue.
-
NCT01390545
2010-022378-15
Details
2016-04-13
Interventional
2-
Veltuzumab
Arthritis Arthritis, Rheu… Rheumatoid Arth…
Trial re-design; no safety issues identified
-