Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00449605
2006-005385-39
Details
2016-05-16
Interventional
3508 
Glimepiride Metformin Rimonabant
Diabetes Mellit…
Company decision taken in light of demands by certain national health authorities
-
NCT02689401
Details
2016-05-13
Interventional
10 
Ferrosoferric O…
Esophageal Neop… Esophageal Canc…
Awaiting additional safety data
-
NCT02529514
Details
2016-05-13
Interventional
4-
Baclofen
Sleep
-
-
NCT02506855
Details
2016-05-13
Interventional
30 
Ropivacaine
Postoperative N… Vomiting Postoperative P…
The investigator decided not to continue the study.
-
NCT02501278
2015-004602-42
Details
2016-05-13
Interventional
20 
Cisplatin
Uterine Cervica…
company (Inovio) is no longer able to support the study
-
NCT01949870
Details
2016-05-13
Interventional
16 
Gemcitabine
Biliary Tract N… Inoperable Loca…
change in the development strategy
Dose escalation stopped after the first cohort due to changes in the drug development strategy. As such, a non-tolerated dose was not determined and the maximum tolerated dose could not be confirmed.
NCT01807286
Details
2016-05-13
Interventional
13 
Dexamethasone Melphalan Pomalidomide
Amyloidosis Immunoglobulin … Myeloma
Sponsor requested termination
-
NCT01289938
2008-003778-16
Details
2016-05-13
Interventional
149 
Diphenhydramine Metoclopramide Promethazine
Metabolism, Inb… Drug Metabolism…
To unsuccessful recruitment of rare UM-genotype. All other planned genotype groups are completed (EM, IM and PM).
-
NCT01202110
Details
2016-05-13
Interventional
210 
Propranolol
Brain Injuries Brain Injuries,… Wounds and Inju… Traumatic Brain…
-
-
NCT00979576
Details
2016-05-13
Interventional
119 
Nintedanib Pemetrexed
Carcinoma, Non-…
-
The trial was planned to comprise of two parts, with the phase II being based on the results of another study. The other study was stopped early due to futility analysis therefore only phase I of the study was completed.
NCT02079480
Details
2016-05-12
Interventional
1130 
Keyhole-limpet …
Healthy Adult V…
-
-
NCT01226823
Details
2016-05-12
Interventional
30 
Ursodeoxycholic…
Cholestasis Cholestasis, In… Pregnancy Compl… Intrahepatic Ch…
Modified insurance requests by a new law released after its approval.
-
NCT01091701
Details
2016-05-12
Interventional
1/20 
Plasma-lyte 148
Stroke
Business reasons
-
NCT01963611
2013-002283-25
Details
2016-05-11
Interventional
2255 
Glatiramer Acet…
Multiple Sclero… Multiple Sclero… Sclerosis Relapsing Remit…
Study was terminated based on sponsor discretion.
Based on Sponsor decision to discontinue the clinical development program of plovamer acetate therapy for multiple sclerosis the trial was prematurely terminated
NCT01717846
Details
2016-05-11
Interventional
40 
Abatacept
Arthritis Arthritis, Rheu… Lymphocytosis Apoptotic DNA D… Rheumatoid Arth… T-cell Lymphocy…
The PI has left UCLA and we do not plan to pursue this study.
-
NCT00892346
Details
2016-05-10
Interventional
3-
Melphalan Thalidomide
Multiple Myelom… Neoplasms, Plas…
No avaliability of melphlan in mainland China
-
NCT02029417
Details
2016-05-09
Interventional
22 
Azacitidine Cytarabine Decitabine Homoharringtoni…
Leukemia Leukemia, Eryth… Leukemia, Megak… Leukemia, Monoc… Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo… Myelodysplastic… Acute Myeloid L… Adult Acute Meg… Adult Acute Min… Adult Acute Mon… Adult Acute Mon… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Erythrole… Adult Pure Eryt… Secondary Acute… Untreated Adult…
Major revisions needed in study
Due to the study's early termination and low accrual no statistical inference of the primary aims were carried forth.
NCT01452100
2010-021467-33
Details
2016-05-09
Interventional
239 
Prednisone
Embolism Embolism, Chole… Cholesterol Emb…
Inclusion default
-
NCT00567879
2007-002449-19
Details
2016-05-09
Interventional
1/256 
Panobinostat Trastuzumab
Breast Neoplasm… Breast Cancer
The study was terminated early due to insufficient evidence of clinical benefit.
-
NCT02762253
Details
2016-05-05
Interventional
2320 
Riboflavin
Keratoconus
No IND submitted to the FDA
-