Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00228891
Details
2016-08-10
Interventional
2/3152 
Insulin Insulin, Globin…
Diabetes Mellit… Diabetic Neurop… Diabetes Mellit…
Administrative
-
NCT00228878
Details
2016-08-10
Interventional
2/3152 
Insulin Insulin Aspart
Diabetes Mellit…
Administrative
-
NCT00228865
Details
2016-08-10
Interventional
2/375 
Insulin Insulin, Globin… Insulin, Isopha…
Diabetes Mellit…
Administrative
-
NCT00361907
Details
2016-08-09
Interventional
2/3105 
Insulin Insulin, Globin…
Diabetes Mellit…
Administrative - Suspended by IRB
-
NCT00538538
Details
2016-08-08
Interventional
10 
Ranibizumab
Hemorrhage Macular Degener… Retinal Hemorrh…
This condition can now be managed in the office with an injection of Lucentis.
-
NCT00112723
Details
2016-08-08
Interventional
1/246 
Alvocidib
Hodgkin Disease Immunoblastic L… Leukemia, Lymph… Leukemia, T-Cel… Leukemia-Lympho… Lymphoma Lymphoma, B-Cel… Lymphoma, B-Cel… Lymphoma, Folli… Lymphoma, Large… Lymphoma, Large… Lymphoma, Mantl… Lymphoma, Non-H… Lymphoma, T-Cel… Lymphoma, T-Cel… Lymphomatoid Gr… Multiple Myelom… Mycoses Mycosis Fungoid… Neoplasms, Plas… Recurrence Sezary Syndrome Waldenstrom Mac… Adult Lymphocyt… Adult Lymphocyt… Adult Mixed Cel… Adult Nodular S… Anaplastic Larg… Angioimmunoblas… Extranodal Marg… Nodal Marginal … Recurrent Adult… Recurrent Adult… Recurrent Adult… Recurrent Adult… Recurrent Adult… Recurrent Adult… Recurrent Cutan… Recurrent Grade… Recurrent Grade… Recurrent Grade… Recurrent Mantl… Recurrent Margi… Recurrent Mycos… Recurrent Small… Refractory Mult… Splenic Margina… Stage I Multipl… Stage II Multip… Stage III Multi… Waldenström Ma…
Administratively Complete
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NCT01528137
Details
2016-08-02
Interventional
14 
Lactoferrin Talactoferrin a…
Carcinoma Carcinoma, Non-… Carcinoma, Squa… Carcinoma, Verr… Head and Neck N… Laryngeal Disea… Laryngeal Neopl… Lung Neoplasms Nasopharyngeal … Neoplasms, Unkn… Oropharyngeal N… Paranasal Sinus… Recurrence Salivary Gland … Squamous Cell C… Tongue Neoplasm… Metastatic Squa… Recurrent Metas… Recurrent Saliv… Recurrent Squam… Recurrent Squam… Recurrent Squam… Recurrent Squam… Recurrent Squam… Recurrent Squam… Recurrent Verru… Recurrent Verru… Salivary Gland … Stage III Saliv… Stage III Squam… Stage III Squam… Stage III Squam… Stage III Squam… Stage III Squam… Stage III Squam… Stage III Verru… Stage III Verru… Stage IV Non-sm… Stage IV Squamo… Stage IV Squamo… Stage IVA Saliv… Stage IVA Squam… Stage IVA Squam… Stage IVA Squam… Stage IVA Squam… Stage IVA Verru… Stage IVA Verru… Stage IVB Saliv… Stage IVB Squam… Stage IVB Squam… Stage IVB Squam… Stage IVB Squam… Stage IVB Verru… Stage IVB Verru… Stage IVC Saliv… Stage IVC Squam… Stage IVC Squam… Stage IVC Squam… Stage IVC Squam… Stage IVC Verru… Stage IVC Verru… Tongue Cancer
Negative data from another trial led to termination of this trial by sponsor.
-
NCT02758067
2015-001749-97
Details
2016-08-01
Interventional
30 
Brexpiprazole Risperidone
Schizophrenia
This study was withdrawn for administrative reasons. There were no safety concerns.
-
NCT01615939
Details
2016-08-01
Interventional
417 
Bupivacaine Ropivacaine
Fracture of Foo…
The study has been terminiated due to minimal subject recruitment
Early termination leading to small numbers of subjects analyzed
NCT01500772
2011-004653-31
Details
2016-08-01
Interventional
36 
Peginterferon a… Ribavirin
Hepatitis Hepatitis A Hepatitis C Hepatitis C, Ch…
-
Due to early termination of the study, none of the planned outcome measures could be evaluated.
NCT01790854
Details
2016-07-29
Interventional
4195 
Prasugrel Hydro…
Acute Coronary … Adverse Reactio…
Low events rate. Scarce economical resources
-
NCT00471809
Details
2016-07-29
Interventional
4
[1 Refs]
-
Azithromycin Budesonide Montelukast Salmeterol Xina…
Asthma
The CARE Network DSMB recommended to the NHLBI that the MARS trial be terminated, based on a futility analysis with 55 randomized children.
-
NCT01605162
Details
2016-07-28
Interventional
28 
10-((4-hydroxyp…
Melanoma Unresectable St… Wild Type BRAF …
-
-
NCT01555073
Details
2016-07-28
Interventional
423 
Celecoxib Pregabalin
Leiomyoma Uterine Artery … Uterine Fibroid…
Subjects did not meet inclusion criteria
Early termination due to lost of follow-up for primary outcome at 3 months
NCT02673866
Details
2016-07-27
Interventional
20 
DS-1971a Pregabalin
Diabetic Neurop… Neuralgia Diabetes Neuropathic Pai…
reassessment of phase 2 study indication
-
NCT01053663
Details
2016-07-27
Interventional
19 
Oseltamivir
Influenza, Huma… Influenza
The study was terminated prematurely after three influenza seasons.
Low number of participants enrolled in the study at the time that the study was terminated limits conclusions that can be derived from the study data.
NCT02640833
2015-003302-16
Details
2016-07-26
Interventional
10 
Venetoclax
Leukemia Leukemia, Lymph… Leukemia, Lymph… Lymphoma Lymphoma, Non-H… Chronic Lymphoc… Non-Hodgkin Lym… Small Lymphocyt…
Study Stopped
-
NCT02627430
Details
2016-07-26
Interventional
10 
Talazoparib
Adenocarcinoma Breast Neoplasm… Carcinoma Cystadenocarcin… Neoplasms Neoplasms, Cyst… Recurrence Triple Negative… Adult Solid Neo… Estrogen Recept… Fallopian Tube … HER2/Neu Negati… Ovarian Serous … Ovarian Serous … Primary Periton… Progesterone Re… Recurrent Breas… Recurrent Fallo… Recurrent Ovari… Recurrent Prima… Triple-Negative…
Other - Protocol moved to Withdrawn
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NCT02317419
2014-002935-32
Details
2016-07-26
Interventional
115 
Gemcitabine LMB-100 Paclitaxel
Cancer
The study was prematurely terminated because the emerging benefit:risk ratio did not justify continuing dosing patients.
-
NCT02099695
Details
2016-07-26
Interventional
30 
Oxybutynin
Hyperhidrosis
The company changed the strategy.
-